Sirtuin 6 mitigated LPS-induced human umbilical vein endothelial cells inflammatory responses through modulating nuclear factor erythroid 2-related factor 2

Overexpressed SIRT6 attenuates cisplatin-induced acute kidney injury by inhibiting ERK1/2 signaling

(2018) Zhongchi Li et al.   KIDNEY INTERNATIONAL

Hepatocyte-specific sirtuin 6 deletion predisposes to nonalcoholic steatohepatitis by up-regulation of Bach1, an Nrf2 repressor

(2017) Sun-O Ka et al.   FASEB JOURNAL

Dexamethasone ameliorates H2S-induced acute lung injury by increasing claudin-5 expression via the PI3K pathway

(2017) P Geng et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Sirtuin 6 protects the brain from cerebral ischemia/reperfusion injury through NRF2 activation

(2017) Wei Zhang et al.   NEUROSCIENCE

Amentoflavone prevents sepsis-associated acute lung injury through Nrf2-GCLc-mediated upregulation of glutathione

(2016) Yuan Zong et al.   ACTA BIOCHIMICA POLONICA

Therapeutic effect of ent -kaur-16-en-19-oic acid on neutrophilic lung inflammation and sepsis is mediated by Nrf2

(2016) Kyun Ha Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2

(2016) Huize Pan et al.   CELL RESEARCH

Senegenin Ameliorate Acute Lung Injury Through Reduction of Oxidative Stress and Inhibition of Inflammation in Cecal Ligation and Puncture-Induced Sepsis Rats

(2016) Chun-Hong Liu et al.   INFLAMMATION

Isovitexin Exerts Anti-Inflammatory and Anti-Oxidant Activities on Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting MAPK and NF-κB and Activating HO-1/Nrf2 Pathways

(2016) Hongming Lv et al.   International Journal of Biological Sciences

BML-111 attenuates acute lung injury in endotoxemic mice

(2016) Min Tang et al.   JOURNAL OF SURGICAL RESEARCH

Infection site is predictive of outcome in acute lung injury associated with severe sepsis and septic shock

(2016) Seitaro Fujishima et al.   RESPIROLOGY

JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks

(2016) Michael Van Meter et al.   Cell Reports

Sirtuin functions and modulation: from chemistry to the clinic

(2016) Vincenzo Carafa et al.   Clinical Epigenetics

Association of Nrf2 with airway pathogenesis: lessons learned from genetic mouse models

(2015) Hye-Youn Cho et al.   ARCHIVES OF TOXICOLOGY

Hydrogen-rich saline ameliorates lung injury associated with cecal ligation and puncture-induced sepsis in rats

(2015) Yu Zhai et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Wedelolactone protects human bronchial epithelial cell injury against cigarette smoke extract-induced oxidant stress and inflammation responses through Nrf2 pathway

(2015) Shumin Ding et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Noblesse Oblige: NRF2 Functions in the Airways

(2014) Hye-Youn Cho et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Suppression of lung inflammation in an LPS-induced acute lung injury model by the fruit hull of Gleditsia sinensis

(2014) Kyun Ha Kim et al.   BMC Complementary and Alternative Medicine

Acute respiratory distress syndrome on the intensive care unit

(2014) Felicity Liew et al.   BRITISH JOURNAL OF HOSPITAL MEDICINE

Protein-based therapies for acute lung injury: targeting neutrophil extracellular traps

(2014) Markus Bosmann et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Rutin decreases lipopolysaccharide-induced acute lung injury via inhibition of oxidative stress and the MAPK–NF-κB pathway

(2014) Chung-Hsin Yeh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ethyl gallate attenuates acute lung injury through Nrf2 signaling

(2013) Kamiya Mehla et al.   BIOCHIMIE

Regulation of Nrf2—an update

(2013) Suryakant K. Niture et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sirtuin 6: a review of biological effects and potential therapeutic properties

(2013) Jade M. Beauharnois et al.   Molecular BioSystems

Suppression of nuclear factor erythroid 2-related factor 2 via extracellular signal-regulated kinase contributes to bleomycin-induced oxidative stress and fibrogenesis

(2013) Rui Liu et al.   TOXICOLOGY LETTERS

Inflammasome-regulated Cytokines Are Critical Mediators of Acute Lung Injury

(2012) Tamás Dolinay et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Liver-Specific Knockdown of IGF-1 Decreases Vascular Oxidative Stress Resistance by Impairing the Nrf2-Dependent Antioxidant Response: A Novel Model of Vascular Aging

(2011) L. C. Bailey-Downs et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Nrf2-regulated PPARγ Expression Is Critical to Protection against Acute Lung Injury in Mice

(2010) Hye-Youn Cho et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Biphasic actions of HMGB1 signaling in inflammation and recovery after stroke

(2010) Kazuhide Hayakawa et al.   Annals of the New York Academy of Sciences

Protective Effect of Rutin on the Ischemia/Reperfusion Induced Damage in Rat Kidney

(2009) Aslı Korkmaz et al.   JOURNAL OF SURGICAL RESEARCH