CryoAPEX – an electron tomography tool for subcellular localization of membrane proteins

Chaperone AMPylation modulates aggregation and toxicity of neurodegenerative disease-associated polypeptides

(2018) Matthias C. Truttmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-quality ultrastructural preservation using cryofixation for 3D electron microscopy of genetically labeled tissues

(2018) Tin Ki Tsang et al.   eLife

Fic-mediated deAMPylation is not dependent on homodimerization and rescues toxic AMPylation in flies

(2017) Amanda K. Casey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Electron microscopy using the genetically encoded APEX2 tag in cultured mammalian cells

(2017) Jeffrey D Martell et al.   Nature Protocols

AMPylation targets the rate-limiting step of BiP’s ATPase cycle for its functional inactivation

(2017) Steffen Preissler et al.   eLife

A Novel Fic (Filamentation Induced by cAMP) Protein fromClostridium difficileReveals an Inhibitory Motif-independent Adenylylation/AMPylation Mechanism

(2016) Emil Dedic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FICD acts bifunctionally to AMPylate and de-AMPylate the endoplasmic reticulum chaperone BiP

(2016) Steffen Preissler et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Unrestrained AMPylation targets cytosolic chaperones and activates the heat shock response

(2016) Matthias C. Truttmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification

(2016) Frédéric V. Stanger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FICD acts bifunctionally to AMPylate and de-AMPylate the endoplasmic reticulum chaperone BiP

(2016) Steffen Preissler et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Caenorhabditis elegans Protein FIC-1 Is an AMPylase That Covalently Modifies Heat-Shock 70 Family Proteins, Translation Elongation Factors and Histones

(2016) Matthias C. Truttmann et al.   PLoS Genetics

FLIPPER, a combinatorial probe for correlated live imaging and electron microscopy, allows identification and quantitative analysis of various cells and organelles

(2015) Jeroen Kuipers et al.   CELL AND TISSUE RESEARCH

HypE-specific Nanobodies as Tools to Modulate HypE-mediated Target AMPylation

(2015) Matthias C. Truttmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel Link between Fic (Filamentation Induced by cAMP)-mediated Adenylylation/AMPylation and the Unfolded Protein Response

(2015) Anwesha Sanyal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global Profiling of Huntingtin-associated protein E (HYPE)-Mediated AMPylation through a Chemical Proteomic Approach

(2015) Malgorzata Broncel et al.   MOLECULAR & CELLULAR PROTEOMICS

Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology

(2015) Alexander Harms et al.   Cell Reports

AMPylation matches BiP activity to client protein load in the endoplasmic reticulum

(2015) Steffen Preissler et al.   eLife

Unfolded Protein Response-regulatedDrosophilaFic (dFic) Protein Reversibly AMPylates BiP Chaperone during Endoplasmic Reticulum Homeostasis

(2014) Hyeilin Ham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Directed evolution of APEX2 for electron microscopy and proximity labeling

(2014) Stephanie S Lam et al.   NATURE METHODS

Crystal Structure of the Human, FIC-Domain Containing Protein HYPE and Implications for Its Functions

(2014) Tom D. Bunney et al.   STRUCTURE

The many faces of Fic: structural and functional aspects of Fic enzymes

(2014) Abel Garcia-Pino et al.   TRENDS IN BIOCHEMICAL SCIENCES

Endoplasmic Reticulum Structure and Interconnections with Other Organelles

(2013) A. R. English et al.   Cold Spring Harbor Perspectives in Biology

Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy

(2012) Jeffrey D Martell et al.   NATURE BIOTECHNOLOGY

Immunolabeling artifacts and the need for live-cell imaging

(2012) Ulrike Schnell et al.   NATURE METHODS

Visual neurotransmission in Drosophila requires expression of Fic in glial capitate projections

(2012) Mokhlasur Rahman et al.   NATURE NEUROSCIENCE

Endoplasmic reticulum–mitochondria contacts: function of the junction

(2012) Ashley A. Rowland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Specific, Sensitive, High-Resolution Detection of Protein Molecules in Eukaryotic Cells Using Metal-Tagging Transmission Electron Microscopy

(2012) Cristina Risco et al.   STRUCTURE

Comparative Analysis ofHistophilus somniImmunoglobulin-binding Protein A (IbpA) with Other Fic Domain-containing Enzymes Reveals Differences in Substrate and Nucleotide Specificities

(2011) Seema Mattoo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of Rab GTPase function by a protein phosphocholine transferase

(2011) Shaeri Mukherjee et al.   NATURE

A Genetically Encoded Tag for Correlated Light and Electron Microscopy of Intact Cells, Tissues, and Organisms

(2011) Xiaokun Shu et al.   PLOS BIOLOGY

Mechanisms Determining the Morphology of the Peripheral ER

(2010) Yoko Shibata et al.   CELL

Histophilus somni IbpA DR2/Fic in Virulence and Immunoprotection at the Natural Host Alveolar Epithelial Barrier

(2010) B. Zekarias et al.   INFECTION AND IMMUNITY

Fluorescent labeling of tetracysteine-tagged proteins in intact cells

(2010) Carsten Hoffmann et al.   Nature Protocols

Structural basis of Fic-mediated adenylylation

(2010) Junyu Xiao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Fic Domain: Regulation of Cell Signaling by Adenylylation

(2009) Carolyn A. Worby et al.   MOLECULAR CELL

Electron microscopy of high pressure frozen samples: bridging the gap between cellular ultrastructure and atomic resolution

(2008) Daniel Studer et al.   HISTOCHEMISTRY AND CELL BIOLOGY

AMPylation of Rho GTPases by Vibrio VopS Disrupts Effector Binding and Downstream Signaling

(2008) M. L. Yarbrough et al.   SCIENCE

The combination of chemical fixation procedures with high pressure freezing and freeze substitution preserves highly labile tissue ultrastructure for electron tomography applications

(2007) Gina E. Sosinsky et al.   JOURNAL OF STRUCTURAL BIOLOGY