The Potential Influence of Bone-Derived Modulators on the Progression of Alzheimer’s Disease

Sex differences in functional and molecular neuroimaging biomarkers of Alzheimer's disease in a monocenter cohort of cognitively normal older adults with subjective memory complaints

(2018) Enrica Cavedo et al.   Alzheimers & Dementia

CTLA-4Ig (abatacept) balances bone anabolic effects of T cells and Wnt-10b with antianabolic effects of osteoblastic sclerostin

(2018) Susanne Roser-Page et al.   Annals of the New York Academy of Sciences

Apolipoprotein E plays crucial roles in maintaining bone mass by promoting osteoblast differentiation via ERK1/2 pathway and by suppressing osteoclast differentiation via c-Fos, NFATc1, and NF-κB pathway

(2018) Takaaki Noguchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A novel role for osteopontin in macrophage-mediated amyloid-β clearance in Alzheimer’s models

(2018) Altan Rentsendorj et al.   BRAIN BEHAVIOR AND IMMUNITY

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration

(2018) Aleksandra Deczkowska et al.   CELL

Calcium signaling and molecular mechanisms underlying neurodegenerative diseases

(2018) Ekaterina Pchitskaya et al.   CELL CALCIUM

Bone-Marrow-Derived Microglia-Like Cells Ameliorate Brain Amyloid Pathology and Cognitive Impairment in a Mouse Model of Alzheimer’s Disease

(2018) Shohei Kawanishi et al.   JOURNAL OF ALZHEIMERS DISEASE

How Can We Improve Osteoporosis Care? A Systematic Review and Meta-Analysis of the Efficacy of Quality Improvement Strategies for Osteoporosis

(2018) Smita Nayak et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteocalcin in the brain: from embryonic development to age-related decline in cognition

(2018) Arnaud Obri et al.   Nature Reviews Endocrinology

Evidence of Wnt/β-catenin alterations in brain and bone of a tauopathy mouse model of Alzheimer's disease

(2018) Christine M. Dengler-Crish et al.   NEUROBIOLOGY OF AGING

Migration-based selections of antibodies that convert bone marrow into trafficking microglia-like cells that reduce brain amyloid β

(2018) Kyung Ho Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Differentiation Balance of Bone Marrow Mesenchymal Stem Cells Is Crucial to Hematopoiesis

(2018) Jiang Wu et al.   Stem Cells International

Wnt signaling in bone, kidney, intestine, and adipose tissue and interorgan interaction in aging

(2018) Di Chen et al.   Annals of the New York Academy of Sciences

Alzheimer Disease

(2018) John E. Morley et al.   CLINICS IN GERIATRIC MEDICINE

Association between Bone Mineral Density and the Risk of Alzheimer's Disease

(2018) Rui Zhou et al.   JOURNAL OF ALZHEIMERS DISEASE

The Role of Osteopontin in Neurodegenerative Diseases

(2018) Miryam Carecchio et al.   JOURNAL OF ALZHEIMERS DISEASE

Cu and Zn interactions with Aβ peptides: consequence of coordination on aggregation and formation of neurotoxic soluble Aβ oligomers

(2018) Monika Rana et al.   Metallomics

The identity and function of microglia in neurodegeneration

(2018) Wilbur M. Song et al.   NATURE IMMUNOLOGY

Loss of canonical Wnt signaling is involved in the pathogenesis of Alzheimer's disease

(2018) NibaldoC Inestrosa et al.   Neural Regeneration Research

Osteogenesis and aging: lessons from mesenchymal stem cells

(2018) Arantza Infante et al.   Stem Cell Research & Therapy

Bone mineral loss and cognitive impairment

(2018) Hyun Goo Kang et al.   MEDICINE

The Molecular and Neuropathological Consequences of Genetic Risk for Alzheimer's Dementia

(2018) Shinya Tasaki et al.   Frontiers in Neuroscience

Skeletal energy homeostasis: a paradigm of endocrine discovery

(2017) Karla J Suchacki et al.   JOURNAL OF ENDOCRINOLOGY

Gpr158 mediates osteocalcin’s regulation of cognition

(2017) Lori Khrimian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dementia prevention, intervention, and care

(2017) Gill Livingston et al.   LANCET

MC4R-dependent suppression of appetite by bone-derived lipocalin 2

(2017) Ioanna Mosialou et al.   NATURE

Interactions of Mitochondria/Metabolism and Calcium Regulation in Alzheimer’s Disease: A Calcinist Point of View

(2017) Gary E. Gibson et al.   NEUROCHEMICAL RESEARCH

The effectiveness of a basic exercise intervention to improve strength and balance in women with osteoporosis

(2017) Montserrat Otero et al.   Clinical Interventions in Aging

Reversal of Synapse Degeneration by Restoring Wnt Signaling in the Adult Hippocampus

(2016) Aude Marzo et al.   CURRENT BIOLOGY

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

G-CSF-mobilized Bone Marrow Mesenchymal Stem Cells Replenish Neural Lineages in Alzheimer’s Disease Mice via CXCR4/SDF-1 Chemotaxis

(2016) Cheng-Chun Wu et al.   MOLECULAR NEUROBIOLOGY

Effect of systemic transplantation of bone marrow-derived mesenchymal stem cells on neuropathology markers in APP/PS1 Alzheimer mice

(2016) Y. Naaldijk et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Therapeutic strategies for Alzheimer's disease in clinical trials

(2016) Justyna Godyń et al.   Pharmacological Reports

The Value of Osteopontin in the Assessment of Bone Mineral Density Status in Postmenopausal Women

(2016) Daniela Fodor et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Periodontitis: a potential risk factor for Alzheimer's disease

(2015) T. L. Cerajewska et al.   BRITISH DENTAL JOURNAL

Macrophage-derived osteopontin induces reactive astrocyte polarization and promotes re-establishment of the blood brain barrier after ischemic stroke

(2015) Michael Gliem et al.   GLIA

Magnesium in Man: Implications for Health and Disease

(2015) Jeroen H. F. de Baaij et al.   PHYSIOLOGICAL REVIEWS

Biology of Bone Tissue: Structure, Function, and Factors That Influence Bone Cells

(2015) Rinaldo Florencio-Silva et al.   Biomed Research International

The role of microglia in human disease: therapeutic tool or target?

(2014) Nathalie Cartier et al.   ACTA NEUROPATHOLOGICA

Inflammation, defective insulin signaling, and neuronal dysfunction in Alzheimer's disease

(2014) Sergio T. Ferreira et al.   Alzheimers & Dementia

Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers

(2014) Christiane Reitz et al.   BIOCHEMICAL PHARMACOLOGY

Osteoporosis and fracture risk in older people

(2014) T. Coughlan et al.   CLINICAL MEDICINE

Osteopontin expression in acute immune response mediates hippocampal synaptogenesis and adaptive outcome following cortical brain injury

(2014) Julie L. Chan et al.   EXPERIMENTAL NEUROLOGY

Advances in the prevention of Alzheimer's disease and dementia

(2014) A. Solomon et al.   JOURNAL OF INTERNAL MEDICINE

Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice

(2014) Saul A Villeda et al.   NATURE MEDICINE

Wnt signaling in the nervous system and in Alzheimer's disease

(2014) N. C. Inestrosa et al.   Journal of Molecular Cell Biology

Therapeutic effects of the transplantation of VEGF overexpressing bone marrow mesenchymal stem cells in the hippocampus of murine model of Alzheimer’s disease

(2014) Karina O. Garcia et al.   Frontiers in Aging Neuroscience

Maternal and Offspring Pools of Osteocalcin Influence Brain Development and Functions

(2013) Franck Oury et al.   CELL

High Serum Osteopontin Levels Are Associated with Low Bone Mineral Density in Postmenopausal Women

(2013) Eun-Hee Cho et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Elevated Osteopontin Levels in Mild Cognitive Impairment and Alzheimer’s Disease

(2013) Yuan Sun et al.   MEDIATORS OF INFLAMMATION

WNT signaling in bone homeostasis and disease: from human mutations to treatments

(2013) Roland Baron et al.   NATURE MEDICINE

Osteocalcin influences fetal brain development and adult brain function

(2013) Claire Greenhill   Nature Reviews Endocrinology

The Secreted Wnt Antagonist Dickkopf-1 Is Required for Amyloid  -Mediated Synaptic Loss

(2012) S. A. Purro et al.   JOURNAL OF NEUROSCIENCE

Skeletal secretion of FGF-23 regulates phosphate and vitamin D metabolism

(2012) L. Darryl Quarles   Nature Reviews Endocrinology

Alzheimer’s Disease and Risk of Hip Fracture: A Meta-Analysis Study

(2012) Yan Zhao et al.   TheScientificWorldJOURNAL

Osteopontin: A key link between immunity, inflammation and the central nervous system

(2012) Amanda Brown   Translational Neuroscience

Disorders of Bone Remodeling

(2011) Xu Feng et al.   Annual Review of Pathology-Mechanisms of Disease

Endocrine Regulation of Male Fertility by the Skeleton

(2011) Franck Oury et al.   CELL

The role of osteocalcin in the endocrine cross-talk between bone remodelling and energy metabolism

(2011) P. Ducy   DIABETOLOGIA

Bone remodelling at a glance

(2011) J. C. Crockett et al.   JOURNAL OF CELL SCIENCE

Osteoporosis: now and the future

(2011) Tilman D Rachner et al.   LANCET

Osteopontin, intrinsic tissue regulator of intractable inflammatory diseases

(2011) Toshimitsu Uede   PATHOLOGY INTERNATIONAL

The great migration of bone marrow-derived stem cells toward the ischemic brain: Therapeutic implications for stroke and other neurological disorders

(2011) Cesar V. Borlongan et al.   PROGRESS IN NEUROBIOLOGY

Combined Effects of Hematopoietic Progenitor Cell Mobilization from Bone Marrow by Granulocyte Colony Stimulating Factor and AMD3100 and Chemotaxis into the Brain Using Stromal Cell-Derived Factor-1α in an Alzheimer's Disease Mouse Model

(2011) Ji-Woong Shin et al.   STEM CELLS

Targeting the hematopoietic system for the treatment of Alzheimer’s disease

(2010) Antoine Lampron et al.   BRAIN BEHAVIOR AND IMMUNITY

Insulin Signaling in Osteoblasts Integrates Bone Remodeling and Energy Metabolism

(2010) Mathieu Ferron et al.   CELL

Current therapeutic targets for the treatment of Alzheimer’s disease

(2010) Joshua D Grill et al.   Expert Review of Neurotherapeutics

Cellular and Molecular Mechanisms of Bone Remodeling

(2010) Liza J. Raggatt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function

(2010) eMalick G. Njie et al.   NEUROBIOLOGY OF AGING

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Powerful beneficial effects of macrophage colony-stimulating factor on  -amyloid deposition and cognitive impairment in Alzheimer's disease

(2009) V. Boissonneault et al.   BRAIN

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

The Role of Granulocyte-Colony Stimulating Factor (G-CSF) in the Healthy Brain: A Characterization of G-CSF-Deficient Mice

(2009) K. Diederich et al.   JOURNAL OF NEUROSCIENCE

Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1ΔE9 mouse model of Alzheimer's disease

(2009) E M Toledo et al.   MOLECULAR PSYCHIATRY

Proteinopathy-induced neuronal senescence: a hypothesis for brain failure in Alzheimer's and other neurodegenerative diseases

(2009) Todd E Golde et al.   Alzheimers Research & Therapy

The role of osteopontin in inflammatory processes

(2009) Susan Amanda Lund et al.   Journal of Cell Communication and Signaling

The basis for disease-modifying treatments for Alzheimer's disease: The Sixth Annual Mild Cognitive Impairment Symposium

(2008) Ranjan Duara et al.   Alzheimers & Dementia

The potential of hematopoietic growth factors for treatment of Alzheimer's disease: a mini-review

(2008) Juan Sanchez-Ramos et al.   BMC NEUROSCIENCE

Bone-marrow-derived microglia: myth or reality?

(2008) Denis Soulet et al.   CURRENT OPINION IN PHARMACOLOGY

Linking Calcium to Aβ and Alzheimer's Disease

(2008) Kim N. Green et al.   NEURON

Mechanisms of microglia accumulation in Alzheimer’s disease: therapeutic implications

(2008) Joseph El Khoury et al.   TRENDS IN PHARMACOLOGICAL SCIENCES