Skeletal secretion of FGF-23 regulates phosphate and vitamin D metabolism

The Associations of Fibroblast Growth Factor 23 and Uncarboxylated Matrix Gla Protein With Mortality in Coronary Artery Disease: The Heart and Soul Study

(2013) Benjamin D. Parker   ANNALS OF INTERNAL MEDICINE

Phylogenomics of phosphoinositide lipid kinases: perspectives on the evolution of second messenger signaling and drug discovery

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Parathyroid hormone receptor signaling in osteocytes increases the expression of fibroblast growth factor-23 in vitro and in vivo

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Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling

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GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo

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FGF receptors control vitamin D and phosphate homeostasis by mediating renal FGF-23 signaling and regulating FGF-23 expression in bone

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Decreased bone density and increased phosphaturia in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase 3

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'Dem bones' are made for more than walking

(2011) L Darryl Quarles   NATURE MEDICINE

Vitamin D Insufficiency

(2011) Clifford J. Rosen   NEW ENGLAND JOURNAL OF MEDICINE

Autosomal-Recessive Hypophosphatemic Rickets Is Associated with an Inactivation Mutation in the ENPP1 Gene

(2010) Varda Levy-Litan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Loss-of-Function ENPP1 Mutations Cause Both Generalized Arterial Calcification of Infancy and Autosomal-Recessive Hypophosphatemic Rickets

(2010) Bettina Lorenz-Depiereux et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype

(2010) Hua Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Circulating Fibroblast Growth Factor-23 Is Associated With Fat Mass and Dyslipidemia in Two Independent Cohorts of Elderly Individuals

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Insulin Receptor Signaling in Osteoblasts Regulates Postnatal Bone Acquisition and Body Composition

(2010) Keertik Fulzele et al.   CELL

Insulin Signaling in Osteoblasts Integrates Bone Remodeling and Energy Metabolism

(2010) Mathieu Ferron et al.   CELL

FoxO1 Is a Positive Regulator of Bone Formation by Favoring Protein Synthesis and Resistance to Oxidative Stress in Osteoblasts

(2010) Marie-Therese Rached et al.   Cell Metabolism

Effects of Dietary Phosphate and Calcium Intake on Fibroblast Growth Factor-23

(2010) M. G. Vervloet et al.   Clinical Journal of the American Society of Nephrology

Vegetarian Compared with Meat Dietary Protein Source and Phosphorus Homeostasis in Chronic Kidney Disease

(2010) S. M. Moe et al.   Clinical Journal of the American Society of Nephrology

Effects of vitamin D replacement therapy on serum FGF23 concentrations in vitamin D-deficient women in short term

(2010) Ayse Kubat Uzum et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

A Phe377del mutation in ANK leads to impaired osteoblastogenesis and osteoclastogenesis in a mouse model for craniometaphyseal dysplasia (CMD)

(2010) I-Ping Chen et al.   HUMAN MOLECULAR GENETICS

ASARM mineralization hypothesis: A bridge too far?

(2010) Valentin David et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Leptin stimulates fibroblast growth factor 23 expression in bone and suppresses renal 1α,25-dihydroxyvitamin D3 synthesis in leptin-deficient ob/ob Mice

(2010) Kiyomi Tsuji et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The osteoblast: An insulin target cell controlling glucose homeostasis

(2010) Thomas L Clemens et al.   JOURNAL OF BONE AND MINERAL RESEARCH

PTH receptor signaling in osteocytes governs periosteal bone formation and intracortical remodeling

(2010) Yumie Rhee et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Dysregulation of renal vitamin D metabolism in the uremic rat

(2010) Christian F. Helvig et al.   KIDNEY INTERNATIONAL

Direct evidence for a causative role of FGF23 in the abnormal renal phosphate handling and vitamin D metabolism in rats with early-stage chronic kidney disease

(2010) Hisashi Hasegawa et al.   KIDNEY INTERNATIONAL

Pilot study of dietary phosphorus restriction and phosphorus binders to target fibroblast growth factor 23 in patients with chronic kidney disease

(2010) T. Isakova et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Relevant use of Klotho in FGF19 subfamily signaling system in vivo

(2010) K.-i. Tomiyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of Cinacalcet and Concurrent Low-Dose Vitamin D on FGF23 Levels in ESRD

(2009) J. B. Wetmore et al.   Clinical Journal of the American Society of Nephrology

Early Control of PTH and FGF23 in Normophosphatemic CKD Patients: A New Target in CKD-MBD Therapy?

(2009) R. B. Oliveira et al.   Clinical Journal of the American Society of Nephrology

Bone Formation Regulates Circulating Concentrations of Fibroblast Growth Factor 23

(2009) Rana Samadfam et al.   ENDOCRINOLOGY

Nuclear Isoforms of Fibroblast Growth Factor 2 Are Novel Inducers of Hypophosphatemia via Modulation of FGF23 and KLOTHO

(2009) Liping Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Familial Tumoral Calcinosis: From Characterization of a Rare Phenotype to the Pathogenesis of Ectopic Calcification

(2009) Eli Sprecher   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Cholecalciferol Supplementation Alters Calcitriol-Responsive Monocyte Proteins and Decreases Inflammatory Cytokines in ESRD

(2009) J. R. Stubbs et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Parathyroid cell resistance to fibroblast growth factor 23 in secondary hyperparathyroidism of chronic kidney disease

(2009) H. Galitzer et al.   KIDNEY INTERNATIONAL

FGF23–parathyroid interaction: implications in chronic kidney disease

(2009) Hirotaka Komaba et al.   KIDNEY INTERNATIONAL

Novel Regulators of Fgf23 Expression and Mineralization in Hyp Bone

(2009) Shiguang Liu et al.   MOLECULAR ENDOCRINOLOGY

Regulation of Fibroblast Growth Factor 23 Production in Bone in Uremic Rats

(2009) Fumie Saji et al.   NEPHRON PHYSIOLOGY

Klotho

(2009) Makoto Kuro-o   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Pathogenic role of Fgf23 in Dmp1-null mice

(2008) Shiguang Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Direct Binding of Integrin αvβ3 to FGF1 Plays a Role in FGF1 Signaling

(2008) Seiji Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypophosphatemia with Elevations in Serum Fibroblast Growth Factor 23 in a Child with Jansen’s Metaphyseal Chondrodysplasia

(2008) Whitney W. Brown et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Endocrine functions of bone in mineral metabolism regulation

(2008) L. Darryl Quarles   JOURNAL OF CLINICAL INVESTIGATION

Peripheral vascular calcification in long-haemodialysis patients: associated factors and survival consequences

(2008) G. Jean et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Fibroblast Growth Factor 23 and Mortality among Patients Undergoing Hemodialysis

(2008) Orlando M. Gutiérrez et al.   NEW ENGLAND JOURNAL OF MEDICINE

Calcimimetics or vitamin D analogs for suppressing parathyroid hormone in end-stage renal disease: time for a paradigm shift?

(2008) James B Wetmore et al.   Nature clinical practice. Nephrology