Curcumin and its Potential for Systemic Targeting of Inflamm-Aging and Metabolic Reprogramming in Cancer
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Curcumin and its Potential for Systemic Targeting of Inflamm-Aging and Metabolic Reprogramming in Cancer
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 5, Pages 1180
Publisher
MDPI AG
Online
2019-03-08
DOI
10.3390/ijms20051180
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Circumventing senescence is associated with stem cell properties and metformin sensitivity
- (2019) Xavier Deschênes-Simard et al. AGING CELL
- Circulating inflammation signature predicts overall survival and relapse-free survival in metastatic colorectal cancer
- (2019) Andreas Varkaris et al. BRITISH JOURNAL OF CANCER
- Cancer statistics, 2019
- (2019) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- IL-17 induces the proliferation and migration of glioma cells through the activation of PI3K/Akt1/NF-κB-p65
- (2019) Bin Wang et al. CANCER LETTERS
- Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson’s Disease
- (2018) Annika Sommer et al. Cell Stem Cell
- Aging and Parkinson's Disease: Inflammaging, neuroinflammation and biological remodeling as key factors in pathogenesis
- (2018) Vittorio Calabrese et al. FREE RADICAL BIOLOGY AND MEDICINE
- Napabucasin and Related Heterocycle-Fused Naphthoquinones as STAT3 Inhibitors with Antiproliferative Activity against Cancer Cells
- (2018) Hauke Löcken et al. JOURNAL OF NATURAL PRODUCTS
- Interleukin 17 and peripheral IL-17-expressing T cells are negatively correlated with the overall survival of head and neck cancer patients
- (2018) Meng-Hua Lee et al. Oncotarget
- Systematic literature review of IL-6 as a biomarker or treatment target in patients with gastric, bile duct, pancreatic and colorectal cancer
- (2018) Noomi Vainer et al. Oncotarget
- Curcumin interacts directly with the Cysteine 259 residue of STAT3 and induces apoptosis in H-Ras transformed human mammary epithelial cells
- (2018) Young-Il Hahn et al. Scientific Reports
- Curcumin targets multiple enzymes involved in the ROS metabolic pathway to suppress tumor cell growth
- (2018) Yonika Arum Larasati et al. Scientific Reports
- Curcumin decreases Warburg effect in cancer cells by down-regulating pyruvate kinase M2 via mTOR-HIF1α inhibition
- (2018) Farid Ahmad Siddiqui et al. Scientific Reports
- Polymeric Nano-Encapsulation of Curcumin Enhances its Anti-Cancer Activity in Breast (MDA-MB231) and Lung (A549) Cancer Cells Through Reduction in Expression of HIF-1α and Nuclear p65 (Rel A)
- (2018) Mohammed N. Khan et al. Current Drug Delivery
- Age and Age-Related Diseases: Role of Inflammation Triggers and Cytokines
- (2018) Irene Maeve Rea et al. Frontiers in Immunology
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- A combination of curcumin and oligomeric proanthocyanidins offer superior anti-tumorigenic properties in colorectal cancer
- (2018) Preethi Ravindranathan et al. Scientific Reports
- The NAD+ Salvage Pathway Supports PHGDH-Driven Serine Biosynthesis
- (2018) J. Patrick Murphy et al. Cell Reports
- Alterations in serum amino-acid profile in the progression of colorectal cancer: associations with systemic inflammation, tumour stage and patient survival
- (2018) Päivi Sirniö et al. BRITISH JOURNAL OF CANCER
- NAD Metabolism in Cancer Therapeutics
- (2018) Keisuke Yaku et al. Frontiers in Oncology
- The synergistic effects of ω-3 fatty acids and nano-curcumin supplementation on tumor necrosis factor (TNF)-α gene expression and serum level in migraine patients
- (2017) Mina Abdolahi et al. IMMUNOGENETICS
- Similarity and Differences in Inflammation-Related Characteristics of the Peripheral Immune System of Patients with Parkinson’s and Alzheimer’s Diseases
- (2017) et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The anti-inflammatory activity of curcumin is mediated by its oxidative metabolites
- (2017) Rebecca L. Edwards et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Menopause Is a Determinant of Breast Aromatase Expression and Its Associations With BMI, Inflammation, and Systemic Markers
- (2017) Kristy A. Brown et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Cancer—Incidence, prevalence and mortality in the oldest-old. A comprehensive review
- (2017) Shantell C. Nolen et al. MECHANISMS OF AGEING AND DEVELOPMENT
- NAD and the aging process: Role in life, death and everything in between
- (2017) Claudia C.S. Chini et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Nicotinamide N -Methyltransferase: More Than a Vitamin B3 Clearance Enzyme
- (2017) Pavlos Pissios TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Anti-tumor bioactivities of curcumin on mice loaded with gastric carcinoma
- (2017) Xiao-Ping Wang et al. Food & Function
- Glucose deprivation elicits phenotypic plasticity via ZEB1-mediated expression of NNMT
- (2017) Justyna Kanska et al. Oncotarget
- Effects of curcumin on serum cytokine concentrations in subjects with metabolic syndrome: A post-hoc analysis of a randomized controlled trial
- (2016) Yunes Panahi et al. BIOMEDICINE & PHARMACOTHERAPY
- Context-dependent effects of cellular senescence in cancer development
- (2016) Pacome Lecot et al. BRITISH JOURNAL OF CANCER
- Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases
- (2016) Ajaikumar B Kunnumakkara et al. BRITISH JOURNAL OF PHARMACOLOGY
- mTORC1-Dependent Metabolic Reprogramming Underlies Escape from Glycolysis Addiction in Cancer Cells
- (2016) Raju V. Pusapati et al. CANCER CELL
- Interleukin-17–Producing Neutrophils Link Inflammatory Stimuli to Disease Progression by Promoting Angiogenesis in Gastric Cancer
- (2016) Tuan-Jie Li et al. CLINICAL CANCER RESEARCH
- Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer
- (2016) Judith E. Unterlass et al. Oncotarget
- In situ Proteomic Profiling of Curcumin Targets in HCT116 Colon Cancer Cell Line
- (2016) Jigang Wang et al. Scientific Reports
- Cranberry proanthocyanidins modulate reactive oxygen species in Barrett’s and esophageal adenocarcinoma cell lines
- (2016) Katherine M. Weh et al. Journal of Berry Research
- Proteome-Wide Profiling of Targets of Cysteine reactive Small Molecules by Using Ethynyl Benziodoxolone Reagents
- (2015) Daniel Abegg et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Curcumin inhibits aerobic glycolysis and induces mitochondrial-mediated apoptosis through hexokinase II in human colorectal cancer cells in vitro
- (2015) Ke Wang et al. ANTI-CANCER DRUGS
- Downregulation of phosphoglycerate dehydrogenase inhibits proliferation and enhances cisplatin sensitivity in cervical adenocarcinoma cells by regulating Bcl-2 and caspase-3
- (2015) Zhang Jing et al. CANCER BIOLOGY & THERAPY
- PKM2 contributes to cancer metabolism
- (2015) Nicholas Wong et al. CANCER LETTERS
- How pyridoxal 5′-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state
- (2015) Giorgio Giardina et al. FEBS Journal
- Multiple effects of curcumin on promoting expression of the exon 7-containing SMN2 transcript
- (2015) Dairong Feng et al. Genes and Nutrition
- Curcumin inhibits Ec109 cell growth via an AMPK-mediated metabolic switch
- (2015) Feng-Juan Zhang et al. LIFE SCIENCES
- SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance
- (2015) Dohoon Kim et al. NATURE
- The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition
- (2015) Henrik Sperber et al. NATURE CELL BIOLOGY
- NRF2 regulates serine biosynthesis in non–small cell lung cancer
- (2015) Gina M DeNicola et al. NATURE GENETICS
- Curcumin and cancer: barriers to obtaining a health claim
- (2015) J. G. Devassy et al. NUTRITION REVIEWS
- miR-615-5p prevents proliferation and migration through negatively regulating serine hydromethyltransferase 2 (SHMT2) in hepatocellular carcinoma
- (2015) Xiaoyu Wu et al. TUMOR BIOLOGY
- Positive correlation between expression level of mitochondrial serine hydroxymethyltransferase and breast cancer grade
- (2015) Ke Yin OncoTargets and Therapy
- Integrated genomic approaches identify major pathways and upstream regulators in late onset Alzheimer’s disease
- (2015) Xinzhong Li et al. Scientific Reports
- Thiol redox homeostasis in neurodegenerative disease
- (2015) Gethin J. McBean et al. Redox Biology
- Multiple effects of curcumin on promoting expression of the exon 7-containing SMN2 transcript
- (2015) Dairong Feng et al. Genes and Nutrition
- Bioinformatics analysis of the serine and glycine pathway in cancer cells
- (2015) Alexey Antonov et al. Oncotarget
- Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation
- (2015) Anna Pastò et al. Oncotarget
- Comparative Oncogenomics Identifies PSMB4 and SHMT2 as Potential Cancer Driver Genes
- (2014) G. Y. Lee et al. CANCER RESEARCH
- Gerometabolites: The pseudohypoxic aging side of cancer oncometabolites
- (2014) JAVIERABEL MENENDEZ MENENDEZ et al. CELL CYCLE
- Curcumin in Combined Cancer Therapy
- (2014) Koraljka Troselj et al. CURRENT PHARMACEUTICAL DESIGN
- Attempts to accelerate wound healing
- (2014) Akira Kasuya et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Long Term Effect of Curcumin in Regulation of Glycolytic Pathway and Angiogenesis via Modulation of Stress Activated Genes in Prevention of Cancer
- (2014) Laxmidhar Das et al. PLoS One
- Serine Catabolism Regulates Mitochondrial Redox Control during Hypoxia
- (2014) J. Ye et al. Cancer Discovery
- Hitting the Golden TORget: Curcumin’s Effects on mTOR Signaling
- (2013) Christopher Beevers et al. Anti-Cancer Agents in Medicinal Chemistry
- Dietary Polyphenols Suppress Elevated Levels of Proinflammatory Mediators and Aromatase in the Mammary Gland of Obese Mice
- (2013) K. Subbaramaiah et al. Cancer Prevention Research
- Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging
- (2013) Ana P. Gomes et al. CELL
- Stress eating and tuning out: Cancer cells re-wire metabolism to counter stress
- (2013) Zachary E. Stine et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Curcumin and its Derivatives: Their Application in Neuropharmacology and Neuroscience in the 21st Century
- (2013) Wing-Hin Lee et al. Current Neuropharmacology
- Reactive oxygen species and the free radical theory of aging
- (2013) Stefan I. Liochev FREE RADICAL BIOLOGY AND MEDICINE
- Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation
- (2013) X. Deschenes-Simard et al. GENES & DEVELOPMENT
- Tumor necrosis factor alpha induces Warburg-like metabolism and is reversed by anti-inflammatory curcumin in breast epithelial cells
- (2013) Roger A. Vaughan et al. INTERNATIONAL JOURNAL OF CANCER
- Proinflammatory Cytokines, Aging, and Age-Related Diseases
- (2013) Martin Michaud et al. Journal of the American Medical Directors Association
- NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink
- (2013) Olesya A Ulanovskaya et al. Nature Chemical Biology
- Th17 Cell-Mediated Neuroinflammation Is Involved in Neurodegeneration of Aβ1-42-Induced Alzheimer’s Disease Model Rats
- (2013) Jun Zhang et al. PLoS One
- Cisplatin Induces a Mitochondrial-ROS Response That Contributes to Cytotoxicity Depending on Mitochondrial Redox Status and Bioenergetic Functions
- (2013) Rossella Marullo et al. PLoS One
- Curcumin-From Molecule to Biological Function
- (2012) Tuba Esatbeyoglu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Binding partners for curcumin in human schwannoma cells: Biologic Implications
- (2012) Laura S. Angelo et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
- (2012) Yoichiro Mitsuishi et al. CANCER CELL
- Serine is a natural ligand and allosteric activator of pyruvate kinase M2
- (2012) Barbara Chaneton et al. NATURE
- Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model
- (2012) Yifeng Xia et al. NATURE CELL BIOLOGY
- Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation
- (2012) M. Jain et al. SCIENCE
- Pharmacodynamics of curcumin as DNA hypomethylation agent in restoring the expression of Nrf2 via promoter CpGs demethylation
- (2011) Tin Oo Khor et al. BIOCHEMICAL PHARMACOLOGY
- Inflammation and Increased Aromatase Expression Occur in the Breast Tissue of Obese Women with Breast Cancer
- (2011) Patrick G. Morris et al. Cancer Prevention Research
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Curcumin Down-Regulates Visfatin Expression and Inhibits Breast Cancer Cell Invasion
- (2011) Su-Ryun Kim et al. ENDOCRINOLOGY
- Purified cranberry proanthocyanidines (PAC-1A) cause pro-apoptotic signaling, ROS generation, cyclophosphamide retention and cytotoxicity in high-risk neuroblastoma cells
- (2011) Nicholi Vorsa INTERNATIONAL JOURNAL OF ONCOLOGY
- Functional genomics reveal that the serine synthesis pathway is essential in breast cancer
- (2011) Richard Possemato et al. NATURE
- Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
- (2011) Jason W Locasale et al. NATURE GENETICS
- Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth
- (2011) Q. Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Warburg Effect and Redox Balance
- (2011) R. B. Hamanaka et al. SCIENCE
- The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
- (2010) Jean-Philippe Coppé et al. Annual Review of Pathology-Mechanisms of Disease
- Network medicine: a network-based approach to human disease
- (2010) Albert-László Barabási et al. NATURE REVIEWS GENETICS
- The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism
- (2010) C. V. Clower et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human pyruvate kinase M2: A multifunctional protein
- (2010) Vibhor Gupta et al. PROTEIN SCIENCE
- Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells
- (2010) M. G. Vander Heiden et al. SCIENCE
- Inflammation and oncogenesis: a vicious connection
- (2009) Sergei I Grivennikov et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Future of Cancer Incidence in the United States: Burdens Upon an Aging, Changing Nation
- (2009) Benjamin D. Smith et al. JOURNAL OF CLINICAL ONCOLOGY
- Increased OXPHOS activity precedes rise in glycolytic rate in H-RasV12/E1A transformed fibroblasts that develop a Warburg phenotype
- (2009) Ad JC de Groof et al. Molecular Cancer
- HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
- (2009) Charles J. David et al. NATURE
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
- (2008) Thomas Kuilman et al. CELL
- The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
- (2008) Ralph J. DeBerardinis et al. Cell Metabolism
- Inflammaging as a prodrome to Alzheimer's disease
- (2008) Brian Giunta et al. Journal of Neuroinflammation
- Oxidative stress in normal and impaired wound repair
- (2008) M SCHAFER et al. PHARMACOLOGICAL RESEARCH
- A chemical genomics screen highlights the essential role of mitochondria in HIF-1 regulation
- (2008) X. Lin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started