Endoplasmic Reticulum Stress and Unfolded Protein Response in Breast Cancer: The Balance between Apoptosis and Autophagy and Its Role in Drug Resistance
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Title
Endoplasmic Reticulum Stress and Unfolded Protein Response in Breast Cancer: The Balance between Apoptosis and Autophagy and Its Role in Drug Resistance
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 4, Pages 857
Publisher
MDPI AG
Online
2019-02-18
DOI
10.3390/ijms20040857
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Note: Only part of the references are listed.- Targeting autophagy in cancer
- (2018) Angelique V. Onorati et al. CANCER
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- (2018) Tomas Gutiérrez et al. CELL CALCIUM
- Endoplasmic Reticulum Stress signalling - from basic mechanisms to clinical applications
- (2018) Aitor Almanza et al. FEBS Journal
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- (2018) J. Andrew Livingston et al. MOLECULAR CANCER THERAPEUTICS
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- (2018) Shenhe Jin et al. ONCOLOGY REPORTS
- Anti-Cancer Natural Products and Their Bioactive Compounds Inducing ER Stress-Mediated Apoptosis: A Review
- (2018) Changmin Kim et al. Nutrients
- The Unfolded Protein Response in Breast Cancer
- (2018) Eoghan McGrath et al. Cancers
- The Roles of Autophagy in Cancer
- (2018) Chul Yun et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Small heat shock proteins: Simplicity meets complexity
- (2018) Martin Haslbeck et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TRAP1: a viable therapeutic target for future cancer treatments?
- (2017) Giacomo Lettini et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Targeting Autophagy in Cancer: Update on Clinical Trials and Novel Inhibitors
- (2017) et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Hsp90α Mediates BMI1 Expression in Breast Cancer Stem/Progenitor Cells through Facilitating Nuclear Translocation of c-Myc and EZH2
- (2017) Yueh-Chun Lee et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Autophagy Roles in the Modulation of DNA Repair Pathways
- (2017) Luciana Gomes et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Crosstalk of ER stress-mediated autophagy and ER-phagy: Involvement of UPR and the core autophagy machinery
- (2017) Shuling Song et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Crosstalk of autophagy and apoptosis: Involvement of the dual role of autophagy under ER stress
- (2017) Shuling Song et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Cancer-specific PERK signaling drives invasion and metastasis through CREB3L1
- (2017) Yu-Xiong Feng et al. Nature Communications
- Endoplasmic reticulum stress signaling and chemotherapy resistance in solid cancers
- (2017) T Avril et al. Oncogenesis
- Increased HSP27 correlates with malignant biological behavior of non-small cell lung cancer and predicts patient’s survival
- (2017) Baowei Sheng et al. Scientific Reports
- Targeting highly expressed extracellular HSP90 in breast cancer stem cells inhibits tumor growthin vitroandin vivo
- (2016) Theodora Stivarou et al. CANCER BIOLOGY & THERAPY
- The Role of the PERK/eIF2α/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum Stress
- (2016) W. Rozpedek et al. CURRENT MOLECULAR MEDICINE
- The integrated stress response
- (2016) Karolina Pakos‐Zebrucka et al. EMBO REPORTS
- Autophagy and the invisible line between life and death
- (2016) Chrisna Swart et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Estrogen signaling and unfolded protein response in breast cancer
- (2016) Gayani Rajapaksa et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Protein misfolding in the endoplasmic reticulum as a conduit to human disease
- (2016) Miao Wang et al. NATURE
- Towards a transcriptome-based theranostic platform for unfavorable breast cancer phenotypes
- (2016) Andrey S. Dobroff et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cell Signaling and Stress Responses
- (2016) Gökhan S. Hotamisligil et al. Cold Spring Harbor Perspectives in Biology
- Nrf2 is the key to chemotherapy resistance in MCF7 breast cancer cells under hypoxia
- (2016) Jhih-Pu Syu et al. Oncotarget
- New insights into the roles of CHOP-induced apoptosis in ER stress
- (2015) Y. Li et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Involvement of the IRE1α-XBP1 Pathway and XBP1s-Dependent Transcriptional Reprogramming in Metabolic Diseases
- (2015) Rong Wu et al. DNA AND CELL BIOLOGY
- Cell death induced by endoplasmic reticulum stress
- (2015) Raffaella Iurlaro et al. FEBS Journal
- Role of GRP78 in promoting therapeutic-resistant breast cancer
- (2015) Katherine L Cook et al. Future Medicinal Chemistry
- Taxol-induced unfolded protein response activation in breast cancer cells exposed to hypoxia: ATF4 activation regulates autophagy and inhibits apoptosis
- (2015) Annick Notte et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Annual Report to the Nation on the Status of Cancer, 1975-2011, Featuring Incidence of Breast Cancer Subtypes by Race/Ethnicity, Poverty, and State
- (2015) Betsy A. Kohler et al. JNCI-Journal of the National Cancer Institute
- Endocrine resistance in breast cancer – An overview and update
- (2015) Robert Clarke et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- ATF4 Gene Network Mediates Cellular Response to the Anticancer PAD Inhibitor YW3-56 in Triple-Negative Breast Cancer Cells
- (2015) S. Wang et al. MOLECULAR CANCER THERAPEUTICS
- Annual Report to the Nation on the Status of Cancer, 1975-2011, Featuring Incidence of Breast Cancer Subtypes by Race/Ethnicity, Poverty, and State
- (2015) Betsy A. Kohler et al. JNCI-Journal of the National Cancer Institute
- Unfolding the Role of Stress Response Signaling in Endocrine Resistant Breast Cancers
- (2015) Robert Clarke et al. Frontiers in Oncology
- Endoplasmic reticulum proteins quality control and the unfolded protein response: The regulative mechanism of organisms against stress injuries
- (2014) Xi Ling Fu et al. BIOFACTORS
- To Be or Not to Be? How Selective Autophagy and Cell Death Govern Cell Fate
- (2014) Douglas R. Green et al. CELL
- Old, new and emerging functions of caspases
- (2014) S Shalini et al. CELL DEATH AND DIFFERENTIATION
- Chloroquine Inhibits Autophagy to Potentiate Antiestrogen Responsiveness in ER+ Breast Cancer
- (2014) K. L. Cook et al. CLINICAL CANCER RESEARCH
- TRAP1 revisited: Novel localizations and functions of a ‘next-generation’ biomarker (Review)
- (2014) MARIA ROSARIA AMOROSO et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway
- (2014) Xi Chen et al. NATURE
- ERβ decreases breast cancer cell survival by regulating the IRE1/XBP-1 pathway
- (2014) G Rajapaksa et al. ONCOGENE
- Anticipatory estrogen activation of the unfolded protein response is linked to cell proliferation and poor survival in estrogen receptor α-positive breast cancer
- (2014) N Andruska et al. ONCOGENE
- Getting RIDD of RNA: IRE1 in cell fate regulation
- (2014) M. Maurel et al. TRENDS IN BIOCHEMICAL SCIENCES
- A Molecular Web: Endoplasmic Reticulum Stress, Inflammation, and Oxidative Stress
- (2014) Namrata Chaudhari et al. Frontiers in Cellular Neuroscience
- HER2/ErbB2 activates HSF1 and thereby controls HSP90 clients including MIF in HER2-overexpressing breast cancer
- (2014) R Schulz et al. Cell Death & Disease
- ER stress-induced cell death mechanisms
- (2013) Renata Sano et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Inhibition of Established Micrometastases by Targeted Drug Delivery via Cell Surface-Associated GRP78
- (2013) Y. R. Miao et al. CLINICAL CANCER RESEARCH
- Targeting GRP78 and antiestrogen resistance in breast cancer
- (2013) Katherine L Cook et al. Future Medicinal Chemistry
- UPR Signal Activation by Luminal Sensor Domains
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- TRAP1 role in endoplasmic reticulum stress protection favors resistance to anthracyclins in breast carcinoma cells
- (2013) LORENZA SISINNI et al. INTERNATIONAL JOURNAL OF ONCOLOGY
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- (2013) Francesca Maddalena et al. Molecular Oncology
- Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2
- (2013) Pallav D Patel et al. Nature Chemical Biology
- Proteomic Profiling Reveals That Resveratrol Inhibits HSP27 Expression and Sensitizes Breast Cancer Cells to Doxorubicin Therapy
- (2013) José Díaz-Chávez et al. PLoS One
- The PERK/ATF4/LAMP3-arm of the unfolded protein response affects radioresistance by interfering with the DNA damage response
- (2013) Anika Nagelkerke et al. RADIOTHERAPY AND ONCOLOGY
- Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1
- (2013) D S Matassa et al. Cell Death & Disease
- Inhibition of heat shock protein (Hsp) 27 potentiates the suppressive effect of Hsp90 inhibitors in targeting breast cancer stem-like cells
- (2012) Che-Hsin Lee et al. BIOCHIMIE
- Activation of the unfolded protein response bypasses trastuzumab-mediated inhibition of the PI-3K pathway
- (2012) Sreekanth Kumandan et al. CANCER LETTERS
- Glucose-Regulated Protein 78 Controls Cross-talk between Apoptosis and Autophagy to Determine Antiestrogen Responsiveness
- (2012) K. L. Cook et al. CANCER RESEARCH
- Endoplasmic Reticulum Stress, the Unfolded Protein Response, Autophagy, and the Integrated Regulation of Breast Cancer Cell Fate
- (2012) R. Clarke et al. CANCER RESEARCH
- An Involvement of Oxidative Stress in Endoplasmic Reticulum Stress and Its Associated Diseases
- (2012) Bidur Bhandary et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cotargeting Stress-Activated Hsp27 and Autophagy as a Combinatorial Strategy to Amplify Endoplasmic Reticular Stress in Prostate Cancer
- (2012) M. Kumano et al. MOLECULAR CANCER THERAPEUTICS
- Trastuzumab: Updated Mechanisms of Action and Resistance in Breast Cancer
- (2012) Thuy Vu et al. Frontiers in Oncology
- TRAP1 and the proteasome regulatory particle TBP7/Rpt3 interact in the endoplasmic reticulum and control cellular ubiquitination of specific mitochondrial proteins
- (2011) M R Amoroso et al. CELL DEATH AND DIFFERENTIATION
- Estrogen receptor mediates a distinct mitochondrial unfolded protein response
- (2011) L. Papa et al. JOURNAL OF CELL SCIENCE
- Heat shock proteins in breast cancer progression–A suitable case for treatment?
- (2010) Stuart K. Calderwood INTERNATIONAL JOURNAL OF HYPERTHERMIA
- Bcl-2 family on guard at the ER
- (2009) Eva Szegezdi et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Activation and clinical significance of the unfolded protein response in breast cancer
- (2009) P Scriven et al. BRITISH JOURNAL OF CANCER
- The ubiquitylation machinery of the endoplasmic reticulum
- (2009) Christian Hirsch et al. NATURE
- Upregulated HSP27 in human breast cancer cells reduces Herceptin susceptibility by increasing Her2 protein stability
- (2008) Se Hun Kang et al. BMC CANCER
- Expression and splicing of the unfolded protein response gene XBP-1 are significantly associated with clinical outcome of endocrine-treated breast cancer
- (2008) Michael P.A. Davies et al. INTERNATIONAL JOURNAL OF CANCER
- Chemical Biology Investigation of Cell Death Pathways Activated by Endoplasmic Reticulum Stress Reveals Cytoprotective Modulators of ASK1
- (2008) InKi Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Proteomic characterization of differentially expressed proteins in breast cancer: Expression of hnRNP H1, RKIP and GRP78 is strongly associated with HER-2/neu status
- (2008) Daohai Zhang et al. Proteomics Clinical Applications
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