Targeting highly expressed extracellular HSP90 in breast cancer stem cells inhibits tumor growthin vitroandin vivo

Parameterization for molecular Gaussian surface and a comparison study of surface mesh generation

(2015) Tiantian Liu et al.   JOURNAL OF MOLECULAR MODELING

Generation of monoclonal antibodies against MGA and comparison of their application in breast cancer detection by immunohistochemistry

(2015) Cuimi Duan et al.   Scientific Reports

Differential nuclear shape dynamics of invasive andnon-invasive breast cancer cells are associated with actin cytoskeleton organization and stability

(2014) Rena Chiotaki et al.   Biochemistry and Cell Biology

Lack of correlation of stem cell markers in breast cancer stem cells

(2014) Y Liu et al.   BRITISH JOURNAL OF CANCER

Breast cancer stem cells: Multiple capacities in tumor metastasis

(2014) Shao-Qing Geng et al.   CANCER LETTERS

FW-04-806 inhibits proliferation and induces apoptosis in human breast cancer cells by binding to N-terminus of Hsp90 and disrupting Hsp90-Cdc37 complex formation

(2014) Wei Huang et al.   Molecular Cancer

A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages

(2014) Haihui Lu et al.   NATURE CELL BIOLOGY

Hsp90 Binds Directly to Fibronectin (FN) and Inhibition Reduces the Extracellular Fibronectin Matrix in Breast Cancer Cells

(2014) Morgan C. Hunter et al.   PLoS One

Notch-EGFR/HER2 Bidirectional Crosstalk in Breast Cancer

(2014) Andrew T. Baker et al.   Frontiers in Oncology

Disulfiram targets cancer stem-like cells and reverses resistance and cross-resistance in acquired paclitaxel-resistant triple-negative breast cancer cells

(2013) P Liu et al.   BRITISH JOURNAL OF CANCER

Role of the IL-6-JAK1-STAT3-Oct-4 pathway in the conversion of non-stem cancer cells into cancer stem-like cells

(2013) Seog-Young Kim et al.   CELLULAR SIGNALLING

Targeted inhibition of Hsp90 by ganetespib is effective across a broad spectrum of breast cancer subtypes

(2013) Julie C. Friedland et al.   INVESTIGATIONAL NEW DRUGS

HSP90 Inhibitors: Current Development and Potential in Cancer Therapy

(2013) Katerina Sidera et al.   Recent Patents on Anti-Cancer Drug Discovery

Cell Surface Cdc37 Participates in Extracellular HSP90 Mediated Cancer Cell Invasion

(2012) Avraam El Hamidieh et al.   PLoS One

P-Cadherin Is Coexpressed with CD44 and CD49f and Mediates Stem Cell Properties in Basal-like Breast Cancer

(2012) André Filipe Vieira et al.   STEM CELLS

Is the Ki-67 labelling index ready for clinical use?

(2011) W. Jonat et al.   ANNALS OF ONCOLOGY

A CD44−/CD24+ phenotype is a poor prognostic marker in early invasive breast cancer

(2011) Mohamed A. H. Ahmed et al.   BREAST CANCER RESEARCH AND TREATMENT

Monoclonal antibody 4C5 prevents activation of MMP2 and MMP9 by disrupting their interaction with extracellular HSP90 and inhibits formation of metastatic breast cancer cell deposits

(2010) Dimitris Stellas et al.   BMC CELL BIOLOGY

Paclitaxel Directly Binds to Bcl-2 and Functionally Mimics Activity of Nur77

(2009) C. Ferlini et al.   CANCER RESEARCH

Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models

(2009) E. Caldas-Lopes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Increasing Complexity of the Cancer Stem Cell Paradigm

(2009) J. M. Rosen et al.   SCIENCE

Inhibition of Hsp90 Down-regulates Mutant Epidermal Growth Factor Receptor (EGFR) Expression and Sensitizes EGFR Mutant Tumors to Paclitaxel

(2008) A. Sawai et al.   CANCER RESEARCH

Die hard: Are cancer stem cells the Bruce Willises of tumor biology?

(2008) Ákos Fábián et al.   CYTOMETRY PART A