Microbiota Metabolite Butyrate Differentially Regulates Th1 and Th17 Cells’ Differentiation and Function in Induction of Colitis

Microbiota-derived short-chain fatty acids promote Th1 cell IL-10 production to maintain intestinal homeostasis

(2018) Mingming Sun et al.   Nature Communications

The Microbial Metabolite Butyrate Induces Expression of Th1-Associated Factors in CD4+ T Cells

(2017) Meike Kespohl et al.   Frontiers in Immunology

RORγt and RORα signature genes in human Th17 cells

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Relationship of Enhanced Butyrate Production by Colonic Butyrate-Producing Bacteria to Immunomodulatory Effects in Normal Mice Fed an Insoluble Fraction of Brassica rapa L.

(2016) Sachi Tanaka et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Butyrate inhibits interleukin-17 and generates Tregs to ameliorate colorectal colitis in rats

(2016) Mingming Zhang et al.   BMC GASTROENTEROLOGY

Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases

(2016) Mingming Sun et al.   JOURNAL OF GASTROENTEROLOGY

Chronically Elevated Levels of Short-Chain Fatty Acids Induce T Cell-Mediated Ureteritis and Hydronephrosis

(2016) J. Park et al.   JOURNAL OF IMMUNOLOGY

mTOR Mediates IL-23 Induction of Neutrophil IL-17 and IL-22 Production

(2016) Feidi Chen et al.   JOURNAL OF IMMUNOLOGY

RAR-related orphan receptor A (RORA): A new susceptibility gene for multiple sclerosis

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IL10-Deficiency in CD4+ T Cells Exacerbates the IFNγ and IL17 Response During Bacteria Induced Colitis

(2015) Virginia Seiffart et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

TGF-β converts Th1 cells into Th17 cells through stimulation of Runx1 expression

(2015) Hou-Pu Liu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Batf-dependent Th17 cells critically regulate IL-23 driven colitis-associated colon cancer

(2015) Elise Punkenburg et al.   GUT

Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine

(2015) Aiden Haghikia et al.   IMMUNITY

T Lymphocyte Dynamics in Inflammatory Bowel Diseases: Role of the Microbiome

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From microbe to man: the role of microbial short chain fatty acid metabolites in host cell biology

(2014) Niranjana Natarajan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Diet, Metabolites, and “Western-Lifestyle” Inflammatory Diseases

(2014) Alison N. Thorburn et al.   IMMUNITY

Role of Blimp-1 in programing Th effector cells into IL-10 producers

(2014) Christian Neumann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Short-chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR–S6K pathway

(2014) J Park et al.   Mucosal Immunology

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

(2014) Aurélien Trompette et al.   NATURE MEDICINE

Gut Microbiota-Derived Short-Chain Fatty Acids, T Cells, and Inflammation

(2014) Chang H. Kim et al.   Immune Network

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

Microbiota innate stimulation is a prerequisite for T cell spontaneous proliferation and induction of experimental colitis

(2010) Ting Feng et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A dominant, coordinated T regulatory cell-IgA response to the intestinal microbiota

(2009) Y. Cong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ

(2008) Xuexian O. Yang et al.   IMMUNITY

Interactions among the transcription factors Runx1, RORγt and Foxp3 regulate the differentiation of interleukin 17–producing T cells

(2008) Fuping Zhang et al.   NATURE IMMUNOLOGY