Aquaporin-4-independent volume dynamics of astroglial endfeet during cortical spreading depression

The role of brain barriers in fluid movement in the CNS: is there a ‘glymphatic’ system?

(2018) N. Joan Abbott et al.   ACTA NEUROPATHOLOGICA

The “glymphatic” mechanism for solute clearance in Alzheimer’s disease: game changer or unproven speculation?

(2018) Alex J. Smith et al.   FASEB JOURNAL

TRPV4 channels contribute to calcium transients in astrocytes and neurons during peri-infarct depolarizations in a stroke model

(2017) Cordula Rakers et al.   GLIA

Cortical Spreading Depression Closes Paravascular Space and Impairs Glymphatic Flow: Implications for Migraine Headache

(2017) Aaron J. Schain et al.   JOURNAL OF NEUROSCIENCE

When size matters: transient receptor potential vanilloid 4 channel as a volume-sensor rather than an osmo-sensor

(2017) Trine L. Toft-Bertelsen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Interstitial solute transport in 3D reconstructed neuropil occurs by diffusion rather than bulk flow

(2017) Karl Erik Holter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma

(2017) Alex J Smith et al.   eLife

Lymphatic Clearance of the Brain: Perivascular, Paravascular and Significance for Neurodegenerative Diseases

(2016) Erik N. T. P. Bakker et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Deletion of Aquaporin-4 Curtails Extracellular Glutamate Elevation in Cortical Spreading Depression in Awake Mice

(2016) Rune Enger et al.   CEREBRAL CORTEX

The continuum of spreading depolarizations in acute cortical lesion development: Examining Leão’s legacy

(2016) Jed A Hartings et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Spatial model of convective solute transport in brain extracellular space does not support a “glymphatic” mechanism

(2016) Byung-Ju Jin et al.   JOURNAL OF GENERAL PHYSIOLOGY

Sensitive red protein calcium indicators for imaging neural activity

(2016) Hod Dana et al.   eLife

Glymphatic solute transport does not require bulk flow

(2016) Mahdi Asgari et al.   Scientific Reports

Dynamics of Ionic Shifts in Cortical Spreading Depression

(2015) Rune Enger et al.   CEREBRAL CORTEX

The speed of swelling kinetics modulates cell volume regulation and calcium signaling in astrocytes: A different point of view on the role of aquaporins

(2015) Maria Grazia Mola et al.   GLIA

A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

(2015) Aleksanteri Aspelund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TRPV4 and AQP4 Channels Synergistically Regulate Cell Volume and Calcium Homeostasis in Retinal Muller Glia

(2015) A. O. Jo et al.   JOURNAL OF NEUROSCIENCE

Chloride Cotransporters as a Molecular Mechanism underlying Spreading Depolarization-Induced Dendritic Beading

(2015) A. B. Steffensen et al.   JOURNAL OF NEUROSCIENCE

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

The Stroke-Migraine Depolarization Continuum

(2015) Jens P. Dreier et al.   NEURON

Spreading Depression, Spreading Depolarizations, and the Cerebral Vasculature

(2015) Cenk Ayata et al.   PHYSIOLOGICAL REVIEWS

Augmentation of Ca2+ signaling in astrocytic endfeet in the latent phase of temporal lobe epilepsy

(2015) Karolina Szokol et al.   Frontiers in Cellular Neuroscience

Cerebral Arterial Pulsation Drives Paravascular CSF-Interstitial Fluid Exchange in the Murine Brain

(2013) J. J. Iliff et al.   JOURNAL OF NEUROSCIENCE

Cortical spreading depression and migraine

(2013) Andrew C. Charles et al.   Nature Reviews Neurology

Garbage Truck of the Brain

(2013) M. Nedergaard   SCIENCE

Persistent astroglial swelling accompanies rapid reversible dendritic injury during stroke-induced spreading depolarizations

(2012) W. Christopher Risher et al.   GLIA

Multiple dynamic representations in the motor cortex during sensorimotor learning

(2012) D. Huber et al.   NATURE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex

(2012) A. S. Thrane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes

(2011) V. Benfenati et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Does single cortical spreading depression elicit pain behaviour in freely moving rats?

(2010) Didem Akcali et al.   CEPHALALGIA

Clinical Relevance of Cortical Spreading Depression in Neurological Disorders: Migraine, Malignant Stroke, Subarachnoid and Intracranial Hemorrhage, and Traumatic Brain Injury

(2010) Martin Lauritzen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema

(2010) A. S. Thrane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Faithful Expression of Multiple Proteins via 2A-Peptide Self-Processing: A Versatile and Reliable Method for Manipulating Brain Circuits

(2009) W. Tang et al.   JOURNAL OF NEUROSCIENCE

A Simplified Baculovirus-AAV Expression Vector System Coupled With One-step Affinity Purification Yields High-titer rAAV Stocks From Insect Cells

(2009) Richard H Smith et al.   MOLECULAR THERAPY