Unexplained Recurrent Miscarriage and Recurrent Implantation Failure: Is There a Place for Immunomodulation?

Low-Molecular-Weight Heparin for Women With Unexplained Recurrent Pregnancy Loss

(2015) Ekkehard Schleussner et al.   ANNALS OF INTERNAL MEDICINE

The efficacy of hydroxychloroquine for obstetrical outcome in anti-phospholipid syndrome: Data from a European multicenter retrospective study

(2015) Arsène Mekinian et al.   AUTOIMMUNITY REVIEWS

Obstetrical APS: Is there a place for hydroxychloroquine to improve the pregnancy outcome?

(2015) Arsene Mekinian et al.   AUTOIMMUNITY REVIEWS

Enoxaparin for prevention of unexplained recurrent miscarriage: a multicenter randomized double-blind placebo-controlled trial

(2015) E. Pasquier et al.   BLOOD

Pregnancy outcome after TNF-α inhibitor therapy during the first trimester: a prospective multicentre cohort study

(2015) Corinna Weber-Schoendorfer et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Comparing the effect of office hysteroscopy with endometrial scratch versus office hysteroscopy on intrauterine insemination outcome: a randomized controlled trial

(2015) Waleed El-Khayat et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

A Randomized Trial of Progesterone in Women with Recurrent Miscarriages

(2015) Arri Coomarasamy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Use of Granulocyte Colony-Stimulating Factor During Pregnancy in Women With Chronic Neutropenia

(2015) Laurence A. Boxer et al.   OBSTETRICS AND GYNECOLOGY

Recurrent miscarriage: causes, evaluation and management

(2015) Carmen Garrido-Gimenez et al.   POSTGRADUATE MEDICAL JOURNAL

Anticorps antiphosphatidyléthanolamine, un marqueur du syndrome des antiphospholipides ?

(2015) Cécile Marie Yelnik et al.   PRESSE MEDICALE

The pro-inflammatory and anti-inflammatory cytokine profile in peripheral blood of women with recurrent implantation failure

(2015) Pei-Yan Liang et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Endometrial Scratch Injury Induces Higher Pregnancy Rate for Women With Unexplained Infertility Undergoing IUI With Ovarian Stimulation

(2015) Ahmed M. Maged et al.   Reproductive Sciences

Chronic inflammatory lesions of the placenta

(2015) Philip J. Katzman   SEMINARS IN PERINATOLOGY

The physiologic and therapeutic role of heparin in implantation and placentation

(2015) Michela Quaranta et al.   PeerJ

Regulatory T Cells: Regulators of Life

(2014) Anne Schumacher et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Intravenous Immunoglobulin G Modulates Peripheral Blood Th17 and Foxp3+Regulatory T Cells in Pregnant Women with Recurrent Pregnancy Loss

(2014) Dong Jae Kim et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Combined oral prednisolone and heparin versus heparin: the effect on peripheral NK cells and clinical outcome in patients with unexplained recurrent miscarriage. A double-blind placebo randomized controlled trial

(2014) Mostafa F. Gomaa et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Chronic histiocytic intervillositis: Outcome, associated diseases and treatment in a multicenter prospective study

(2014) Arsène Mekinian et al.   AUTOIMMUNITY

Intravenous immunoglobulin treatment for secondary recurrent miscarriage: a randomised, double-blind, placebo-controlled trial

(2014) OB Christiansen et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Safety of anti-TNF therapy in inflammatory bowel disease during pregnancy

(2014) Nabeel Khan et al.   Expert Opinion On Drug Safety

Immunomodulatory treatment with intravenous immunoglobulin and prednisone in patients with recurrent miscarriage and implantation failure after in vitro fertilization/intracytoplasmic sperm injection

(2014) Kathinka Marie Nyborg et al.   FERTILITY AND STERILITY

A randomized clinical trial of endometrial perfusion with granulocyte colony-stimulating factor in in vitro fertilization cycles: impact on endometrial thickness and clinical pregnancy rates

(2014) David H. Barad et al.   FERTILITY AND STERILITY

Hydroxychloroquine restores trophoblast fusion affected by antiphospholipid antibodies

(2014) T. Marchetti et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Potentiating maternal immune tolerance in pregnancy: A new challenging role for regulatory T cells

(2014) J. Alijotas-Reig et al.   PLACENTA

Maternal Floor Infarction/Massive Perivillous Fibrin Deposition: A Manifestation of Maternal Antifetal Rejection?

(2013) Roberto Romero et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Granulocyte-Colony Stimulating Factor as Treatment Option in Patients with Recurrent Miscarriage

(2013) Claudia Santjohanser et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

The impact of primary Sjogren's syndrome on pregnancy outcome: Our series and review of the literature

(2013) Sara De Carolis et al.   AUTOIMMUNITY REVIEWS

Effect of prior birth and miscarriage frequency on the prevalence of acquired and congenital uterine anomalies in women with recurrent miscarriage: a cross-sectional study

(2013) Carolyn R. Jaslow et al.   FERTILITY AND STERILITY

A feasibility trial of screening women with idiopathic recurrent miscarriage for high uterine natural killer cell density and randomizing to prednisolone or placebo when pregnant

(2013) A.-W. Tang et al.   HUMAN REPRODUCTION

Vitamin D deficiency may be a risk factor for recurrent pregnancy losses by increasing cellular immunity and autoimmunity

(2013) Kuniaki Ota et al.   HUMAN REPRODUCTION

Adjunct low-molecular-weight heparin to improve live birth rate after recurrent implantation failure: a systematic review and meta-analysis

(2013) N. Potdar et al.   HUMAN REPRODUCTION UPDATE

Levothyroxine treatment and pregnancy outcome in women with subclinical hypothyroidism undergoing assisted reproduction technologies: systematic review and meta-analysis of RCTs

(2013) B. Velkeniers et al.   HUMAN REPRODUCTION UPDATE

Outcome of Pregnancy in Italian Patients with Primary Sjogren Syndrome

(2013) R. Priori et al.   JOURNAL OF RHEUMATOLOGY

Current Concepts and New Trends in the Diagnosis and Management of Recurrent Miscarriage

(2013) Jaume Alijotas-Reig et al.   OBSTETRICAL & GYNECOLOGICAL SURVEY

Anti-SSA Ro52/Ro60 antibody testing by immunodot could help the diagnosis of Sjogren’s syndrome in the absence of anti-SSA/SSB antibodies by ELISA

(2013) Arsène Mekinian et al.   RHEUMATOLOGY

Tumor necrosis factor-α inhibitor therapy and fetal risk: A systematic literature review

(2013) Renée M Marchioni   WORLD JOURNAL OF GASTROENTEROLOGY

Intravenous Immunoglobulin Treatment Increased Live Birth Rate in a Spanish Cohort of Women with Recurrent Reproductive Failure and Expanded CD56+ Cells

(2012) Manuela Moraru et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Die-Off Ratio Correlates with Increased TNF-α:IL-10 Ratio and Decreased IVF Success Rates Correctable with Humira

(2012) Edward E. Winger et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Does Immunotherapy for Treatment of Reproductive Failure Enhance Live Births?

(2012) Carolyn B. Coulam et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Maternal Use of Hydroxychloroquine Is Associated With a Reduced Risk of Recurrent Anti-SSA/Ro-Antibody–Associated Cardiac Manifestations of Neonatal Lupus

(2012) Peter M. Izmirly et al.   CIRCULATION

Recurrent IVF failure: other factors

(2012) Alan S. Penzias   FERTILITY AND STERILITY

Treatment of thyroid disorders before conception and in early pregnancy: a systematic review

(2012) R. Vissenberg et al.   HUMAN REPRODUCTION UPDATE

Efficacy of three different antithrombotic regimens on pregnancy outcome in pregnant women affected by recurrent pregnancy loss

(2012) A. Giancotti et al.   Journal of Maternal-Fetal & Neonatal Medicine

Prednisolone for repeated implantation failure associated with high natural killer cell levels

(2012) M. Krigstein et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Enhancement of peripheral blood CD56dim cell and NK cell cytotoxicity in women with recurrent spontaneous abortion or in vitro fertilization failure

(2012) Najmeh Karami et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Treatment of refractory obstetric antiphospholipid syndrome: the state of the art and new trends in the therapeutic management

(2012) J Alijotas-Reig   LUPUS

Endometrial injury to overcome recurrent embryo implantation failure: a systematic review and meta-analysis

(2012) Neelam Potdar et al.   REPRODUCTIVE BIOMEDICINE ONLINE

In vitro up-regulation of HLA-G using dexamethasone and hydrocortisone in first-trimester trophoblast cells of women experiencing recurrent miscarriage

(2012) A. Akhter et al.   TISSUE ANTIGENS

A Unique Preliminary Study on Placental Apoptosis in Mice with Passive Immunization of Anti-Phosphatidylethanolamine Antibodies and Anti-Factor XII Antibodies

(2011) Shanmugam Velayuthaprabhu et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Degree of TNF-α/IL-10 Cytokine Elevation Correlates With IVF Success Rates in Women Undergoing Treatment With Adalimumab (Humira) and IVIG

(2011) Edward E. Winger et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Anti-TNF therapies and pregnancy: outcome of 130 pregnancies in the British Society for Rheumatology Biologics Register

(2011) S. M. M. Verstappen et al.   ANNALS OF THE RHEUMATIC DISEASES

Thrombophilia and outcomes of assisted reproduction technologies: a systematic review and meta-analysis

(2011) M. Di Nisio et al.   BLOOD

An imbalance in interleukin-17-producing T and Foxp3+ regulatory T cells in women with idiopathic recurrent pregnancy loss

(2011) S. K. Lee et al.   HUMAN REPRODUCTION

Intravenous immunoglobulin and idiopathic secondary recurrent miscarriage: methodological problems

(2011) D. A. Clark   HUMAN REPRODUCTION

Investigation of systemic inflammatory response in first trimester pregnancy failure

(2011) J. Calleja-Agius et al.   HUMAN REPRODUCTION

Localization of angiogenic growth factors and their receptors in the human endometrium throughout the menstrual cycle and in recurrent miscarriage

(2011) Gendie E. Lash et al.   HUMAN REPRODUCTION

New pre-conception immune biomarkers for clinical practice: interleukin-18, interleukin-15 and TWEAK on the endometrial side, G-CSF on the follicular side

(2011) N. Lédée et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Intralipid therapy for recurrent implantation failure: new hope or false dawn?

(2011) N. Shreeve et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Ocular Toxicity in Children Exposed in Utero to Antimalarial Drugs: Review of the Literature

(2011) ALLA OSADCHY et al.   JOURNAL OF RHEUMATOLOGY

Decidual CD4+CD25+CD127dim/− regulatory T cells in patients with unexplained recurrent spontaneous miscarriage

(2010) Shi Hua Bao et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

High pregnancy rates with administration of granulocyte colony-stimulating factor in ART-patients with repetitive implantation failure and lacking killer-cell immunglobulin-like receptors

(2010) W. Wurfel et al.   HUMAN REPRODUCTION

Intravenous immunoglobulin and idiopathic secondary recurrent miscarriage: a multicentered randomized placebo-controlled trial

(2010) M. D. Stephenson et al.   HUMAN REPRODUCTION

Increased prevalence of T helper 17 (Th17) cells in peripheral blood and decidua in unexplained recurrent spontaneous abortion patients

(2010) Wen-Juan Wang et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Anti-TNFα therapy in immune-mediated subfertility: State of the art

(2010) David A. Clark   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Uterine natural killer cells in peri-implantation endometrium from women with repeated implantation failure after IVF

(2010) Elizabeth Tuckerman et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The frequency, clinical significance and pathological features of chronic chorioamnionitis: a lesion associated with spontaneous preterm birth

(2010) Chong Jai Kim et al.   MODERN PATHOLOGY

Aspirin plus Heparin or Aspirin Alone in Women with Recurrent Miscarriage

(2010) Stef P. Kaandorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Heparin Treatment in Antiphospholipid Syndrome With Recurrent Pregnancy Loss

(2010) Christine A. Clark et al.   OBSTETRICS AND GYNECOLOGY

Chronic histiocytic intervillositis of unknown etiology: Clinical features in a consecutive series of 69 cases

(2010) V. Marchaudon et al.   PLACENTA

Thromboprophylaxis for recurrent miscarriage in women with or without thrombophilia

(2010) Jantien Visser et al.   THROMBOSIS AND HAEMOSTASIS

COMMENTARY: Should Anti-TNF-α Therapy be Offered to Patients with Infertility and Recurrent Spontaneous Abortion?*

(2009) David A. Clark   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

SHORT COMMUNICATION: Circulating and Decidual Th17 Cell Levels in Healthy Pregnancy

(2009) Akitoshi Nakashima et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Prevalence of antiphospholipid antibodies among women experiencing unexplained infertility and recurrent implantation failure

(2009) Ruben Sauer et al.   FERTILITY AND STERILITY

Detailed analysis of peripheral blood natural killer (NK) cells in women with recurrent miscarriage

(2009) K. King et al.   HUMAN REPRODUCTION

Endometrial secretion analysis identifies a cytokine profile predictive of pregnancy in IVF

(2009) C.M. Boomsma et al.   HUMAN REPRODUCTION

Use of granulocyte colony-stimulating factor for the treatment of unexplained recurrent miscarriage: a randomised controlled trial

(2009) F. Scarpellini et al.   HUMAN REPRODUCTION

Progesterone-induced blocking factor (PIBF) modulates cytokine production by lymphocytes from women with recurrent miscarriage or preterm delivery

(2009) R. Raghupathy et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The Role of Growth Factors and Cytokines during Implantation: Endocrine and Paracrine Interactions

(2009) Ozlem Guzeloglu-Kayisli et al.   SEMINARS IN REPRODUCTIVE MEDICINE

ORIGINAL ARTICLE: Duration of Intralipid’s Suppressive Effect on NK Cell’s Functional Activity

(2008) Roumen G. Roussev et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

ORIGINAL ARTICLE: Treatment with Tumor Necrosis Factor Inhibitors and Intravenous Immunoglobulin Improves Live Birth Rates in Women with Recurrent Spontaneous Abortion

(2008) Edward E. Winger et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review

(2008) G Ruiz-Irastorza et al.   ANNALS OF THE RHEUMATIC DISEASES

Uterine natural killer cells and angiogenesis in recurrent reproductive failure

(2008) S. Quenby et al.   HUMAN REPRODUCTION

Decidual vascularization and the expression of angiogenic growth factors and proteases in first trimester spontaneous abortions

(2008) M. Plaisier et al.   HUMAN REPRODUCTION

Cytokines and chemokines in follicular fluids and potential of the corresponding embryo: the role of granulocyte colony-stimulating factor

(2008) N. Ledee et al.   HUMAN REPRODUCTION

Intracellular cytokine expression of peripheral blood natural killer cell subsets in women with recurrent spontaneous abortions and implantation failures

(2007) Atsushi Fukui et al.   FERTILITY AND STERILITY