TLR signals license CD8 T cells to destroy oligodendrocytes expressing an antigen shared with a Listeria pathogen

Theiler's murine encephalomyelitis virus infection of SJL/J and C57BL/6J mice: Models for multiple sclerosis and epilepsy

(2017) Ana Beatriz DePaula-Silva et al.   JOURNAL OF NEUROIMMUNOLOGY

Suppression of autoimmune demyelinating disease by preferential stimulation of CNS-specific CD8 T cells using Listeria-encoded neuroantigen

(2017) Farah R. Itani et al.   Scientific Reports

Multiple sclerosis: experimental models and reality

(2016) Hans Lassmann et al.   ACTA NEUROPATHOLOGICA

CD8+ T-Cells as Immune Regulators of Multiple Sclerosis

(2015) Sushmita Sinha et al.   Frontiers in Immunology

Molecular Mimicry between Neurons and an Intracerebral Pathogen Induces a CD8 T Cell-Mediated Autoimmune Disease

(2014) M. Sanchez-Ruiz et al.   JOURNAL OF IMMUNOLOGY

The impact of single and pairwise Toll-like receptor activation on neuroinflammation and neurodegeneration

(2014) Karen Rosenberger et al.   Journal of Neuroinflammation

TLR7 signaling exacerbates CNS autoimmunity through downregulation of Foxp3+Treg cells

(2013) Patrice H. Lalive et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Disease-Ameliorating Function of Autoregulatory CD8 T Cells Is Mediated by Targeting of Encephalitogenic CD4 T Cells in Experimental Autoimmune Encephalomyelitis

(2013) S. B. Ortega et al.   JOURNAL OF IMMUNOLOGY

Oligodendrocytes Enforce Immune Tolerance of the Uninfected Brain by Purging the Peripheral Repertoire of Autoreactive CD8+ T Cells

(2012) Shin-Young Na et al.   IMMUNITY

A Transgenic Model of Central Nervous System Autoimmunity Mediated by CD4+ and CD8+ T and B Cells

(2012) A. C. Anderson et al.   JOURNAL OF IMMUNOLOGY

Antiviral CD8+ T cells cause an experimental autoimmune encephalomyelitis-like disease in naive mice

(2012) Jane E. Libbey et al.   JOURNAL OF NEUROVIROLOGY

Treatment of Autoimmune Inflammation by a TLR7 Ligand Regulating the Innate Immune System

(2012) Tomoko Hayashi et al.   PLoS One

Pathogenic CD8 T Cells in Multiple Sclerosis and Its Experimental Models

(2012) Eric S. Huseby et al.   Frontiers in Immunology

TLR7 and TLR9 Trigger Distinct Neuroinflammatory Responses in the CNS

(2011) Niranjan B. Butchi et al.   AMERICAN JOURNAL OF PATHOLOGY

Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential

(2011) Mark L. Hanke et al.   CLINICAL SCIENCE

Toll-like receptors 2 and 3 agonists differentially affect oligodendrocyte survival, differentiation, and myelin membrane formation

(2011) Malika Bsibsi et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The TLR7 agonist, imiquimod, increases IFN-β production and reduces the severity of experimental autoimmune encephalomyelitis

(2010) Kate O'Brien et al.   JOURNAL OF NEUROIMMUNOLOGY

Viral infection triggers central nervous system autoimmunity via activation of CD8+ T cells expressing dual TCRs

(2010) Qingyong Ji et al.   NATURE IMMUNOLOGY

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

CD4 T Cells Mediate Axonal Damage and Spinal Cord Motor Neuron Apoptosis in Murine P0106–125-Induced Experimental Autoimmune Neuritis

(2008) Anna Brunn et al.   AMERICAN JOURNAL OF PATHOLOGY

Naïve CD8 T-cells initiate spontaneous autoimmunity to a sequestered model antigen of the central nervous system

(2008) Shin-Young Na et al.   BRAIN

Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis

(2008) Monica Marta et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Toll-like Receptors Activate Innate and Adaptive Immunity by using Dendritic Cell-Intrinsic and -Extrinsic Mechanisms

(2008) Baidong Hou et al.   IMMUNITY

Mechanisms of inflammation induced tissue injury in multiple sclerosis

(2008) Hans Lassmann   JOURNAL OF THE NEUROLOGICAL SCIENCES

Central nervous system Toll-like receptor expression in response to Theiler's murine encephalomyelitis virus-induced demyelination disease in resistant and susceptible mouse strains

(2008) Nicolas P Turrin   Virology Journal