Vitamin D protects against particles-caused lung injury through induction of autophagy in an Nrf2-dependent manner

Oxygen content determines the bio-reactivity and toxicity profiles of carbon black particles

(2018) Yakun Wu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Effects on IL-1β signaling activation induced by water and organic extracts of fine particulate matter (PM 2.5 ) in vitro

(2018) Fanfan Xu et al.   ENVIRONMENTAL POLLUTION

AMPKα2 deficiency exacerbates long-term PM 2.5 exposure-induced lung injury and cardiac dysfunction

(2018) Hongyun Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Effects of Vitamin D Supplementation on Biomarkers of Inflammation and Oxidative Stress in Diabetic Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

(2018) Mohammad Mansournia et al.   HORMONE AND METABOLIC RESEARCH

1,25-Dihydroxy vitamin D prevents tumorigenesis by inhibiting oxidative stress and inducing tumor cellular senescence in mice

(2018) Lulu Chen et al.   INTERNATIONAL JOURNAL OF CANCER

Safer approaches to therapeutic modulation of TGF-β signaling for respiratory disease

(2018) Philippe Lachapelle et al.   PHARMACOLOGY & THERAPEUTICS

Particle-related exposure, dose and lung cancer risk of primary school children in two European countries

(2018) A. Pacitto et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Bixin protects against particle-induced long-term lung injury in an NRF2-dependent manner

(2018) Lian Xue et al.   Toxicology Research

Therapeutic potential of bixin in PM2.5 particles-induced lung injury in an Nrf2-dependent manner

(2018) Hong Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of fine particulate matter and its constituents on emergency room visits for asthma in southern Taiwan during 2008–2010: a population-based study

(2017) Su-Lun Hwang et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Fine particulate matter on hospital admissions for acute exacerbation of chronic obstructive pulmonary disease in southwestern Taiwan during 2006–2012

(2017) Su-Lun Hwang et al.   INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH

PM2.5-induced lung inflammation in mice: Differences of inflammatory response in macrophages and type II alveolar cells

(2017) Miao He et al.   JOURNAL OF APPLIED TOXICOLOGY

Activation of Nrf2-Antioxidant Signaling by 1,25-Dihydroxycholecalciferol Prevents Leptin-Induced Oxidative Stress and Inflammation in Human Endothelial Cells

(2017) Thaisa M Teixeira et al.   JOURNAL OF NUTRITION

The effects of NRF2 modulation on the initiation and progression of chemically and genetically induced lung cancer

(2017) Shasha Tao et al.   MOLECULAR CARCINOGENESIS

Protective effects of oleanolic acid on oxidative stress and the expression of cytokines and collagen by the AKT/NF-κB pathway in silicotic rats

(2017) Hai-Bing Peng et al.   Molecular Medicine Reports

Bosutinib Therapy Ameliorates Lung Inflammation and Fibrosis in Experimental Silicosis

(2017) Priscila J. Carneiro et al.   Frontiers in Physiology

Nrf2 activation in the treatment of neurodegenerative diseases: a focus on its role in mitochondrial bioenergetics and function

(2016) Noemí Esteras et al.   BIOLOGICAL CHEMISTRY

Cancer Mortality Risks from Long-term Exposure to Ambient Fine Particle

(2016) C. M. Wong et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Earthworm extract attenuates silica-induced pulmonary fibrosis through Nrf2-dependent mechanisms

(2016) Jingjin Yang et al.   LABORATORY INVESTIGATION

The protective role of vitamin D3 in a murine model of asthma via the suppression of TGF-β/Smad signaling and activation of the Nrf2/HO-1 pathway

(2016) Zhihui Wang et al.   Molecular Medicine Reports

Lipoicmethylenedioxyphenol Reduces Experimental Atherosclerosis through Activation of Nrf2 Signaling

(2016) Zhekang Ying et al.   PLoS One

Alteration of canonical and non-canonical WNT-signaling by crystalline silica in human lung epithelial cells

(2016) Timothy N. Perkins et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Association between Atmospheric Fine Particulate Matter and Hospital Admissions for Chronic Obstructive Pulmonary Disease in Southwestern Taiwan: A Population-Based Study

(2016) Su-Lun Hwang et al.   International Journal of Environmental Research and Public Health

Dasatinib Reduces Lung Inflammation and Fibrosis in Acute Experimental Silicosis

(2016) Fernanda Ferreira Cruz et al.   PLoS One

Bixin protects mice against ventilation-induced lung injury in an NRF2-dependent manner

(2016) Shasha Tao et al.   Scientific Reports

An Essential Role of NRF2 in Diabetic Wound Healing

(2015) Min Long et al.   DIABETES

p62 links autophagy and Nrf2 signaling

(2015) Tao Jiang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Silica nanoparticles induce oxidative stress, inflammation, and endothelial dysfunction in vitro via activation of the MAPK/Nrf2 pathway and nuclear factor-κB signaling

(2015) Caixia Guo et al.   International Journal of Nanomedicine

Oncogenic KRAS Confers Chemoresistance by Upregulating NRF2

(2014) S. Tao et al.   CANCER RESEARCH

Update on the Biologic Role of the Vitamin D Endocrine System

(2014) Adriana Dusso   Current Vascular Pharmacology

Tanshinone I Activates the Nrf2-Dependent Antioxidant Response and Protects Against As(III)-Induced Lung Inflammation In Vitro and In Vivo

(2013) Shasha Tao et al.   ANTIOXIDANTS & REDOX SIGNALING

Silica: A lung carcinogen

(2013) Kyle Steenland et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Nitric oxide–mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection

(2013) Manfred Nairz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Marked 25-hydroxyvitamin D deficiency is associated with poor prognosis in patients with alcoholic liver disease

(2013) Eric Trépo et al.   JOURNAL OF HEPATOLOGY

The Nrf2-inducers tanshinone I and dihydrotanshinone protect human skin cells and reconstructed human skin against solar simulated UV

(2013) Shasha Tao et al.   Redox Biology

Vitamin D and lung disease

(2012) Paul E Pfeffer et al.   THORAX

Sulforaphane prevents pulmonary damage in response to inhaled arsenic by activating the Nrf2-defense response

(2012) Yi Zheng et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Fas/FasL pathway-mediated alveolar macrophage apoptosis involved in human silicosis

(2011) San-qiao Yao et al.   APOPTOSIS

Therapeutic Potential of Nrf2 Activators in Streptozotocin-Induced Diabetic Nephropathy

(2011) Hongting Zheng et al.   DIABETES

Physical and Functional Interaction of Sequestosome 1 with Keap1 Regulates the Keap1-Nrf2 Cell Defense Pathway

(2010) Ian M. Copple et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

(2010) Ashish Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62

(2010) A. Lau et al.   MOLECULAR AND CELLULAR BIOLOGY

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

(2010) Masaaki Komatsu et al.   NATURE CELL BIOLOGY

Vitamin D: An Evidence-Based Review

(2009) T. Kulie et al.   Journal of the American Board of Family Medicine

Dual roles of Nrf2 in cancer

(2008) A LAU et al.   PHARMACOLOGICAL RESEARCH