B cells in chronic obstructive pulmonary disease: moving to center stage

Dendritic cells inversely regulate airway inflammation in cigarette smoke-exposed mice

(2016) Masoumeh Ezzati Givi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

A systemic defect in Toll-like receptor 4 signaling increases lipopolysaccharide-induced suppression of IL-2-dependent T-cell proliferation in COPD

(2016) Jürgen Knobloch et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Induction and regulation of murine emphysema by elastin peptides

(2016) Mehdi Sellami et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

TLR9 expression is required for the development of cigarette smoke-induced emphysema in mice

(2016) Robert F. Foronjy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cigarette smoke-induced necroptosis and DAMP release trigger neutrophilic airway inflammation in mice

(2016) Simon D. Pouwels et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Microbiota Promotes Chronic Pulmonary Inflammation by Enhancing IL-17A and Autoantibodies

(2016) Koshika Yadava et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Network Analysis of Lung Transcriptomics Reveals a Distinct B-Cell Signature in Emphysema

(2016) Rosa Faner et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Airway bacteria drive a progressive COPD-like phenotype in mice with polymeric immunoglobulin receptor deficiency

(2016) Bradley W. Richmond et al.   Nature Communications

Local T/B cooperation in inflamed tissues is supported by T follicular helper-like cells

(2016) Dana Vu Van et al.   Nature Communications

Airways inflammation and treatment during acute exacerbations of COPD

(2016) Erik Bathoorn   International Journal of Chronic Obstructive Pulmonary Disease

Roles for proteinases in the pathogenesis of chronic obstructive pulmonary disease

(2016) Caroline Owen   International Journal of Chronic Obstructive Pulmonary Disease

ncRNA-regulated immune response and its role in inflammatory lung diseases

(2015) Na Xie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The matrikine PGP as a potential biomarker in COPD

(2015) Mojtaba Abdul Roda et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Chemokine receptors and their therapeutic opportunities in diseased lung: Far beyond leukocyte trafficking

(2015) Tereza Tomankova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Role of B Cell–Activating Factor in Chronic Obstructive Pulmonary Disease

(2015) Leen J. M. Seys et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IL-17A Is Elevated in End-Stage Chronic Obstructive Pulmonary Disease and Contributes to Cigarette Smoke–induced Lymphoid Neogenesis

(2015) Abraham B. Roos et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

B Cell–Activating Factor. An Orchestrator of Lymphoid Follicles in Severe Chronic Obstructive Pulmonary Disease

(2015) Francesca Polverino et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Host Response to the Lung Microbiome in Chronic Obstructive Pulmonary Disease

(2015) Marc A. Sze et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Immune Activation in α1-Antitrypsin-Deficiency Emphysema. Beyond the Protease–Antiprotease Paradigm

(2015) Simonetta Baraldo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Chemokine (C-X-C motif) receptor 3-positive B cells link interleukin-17 inflammation to protumorigenic macrophage polarization in human hepatocellular carcinoma

(2015) Rui-Xian Liu et al.   HEPATOLOGY

Regulatory B Cells: Origin, Phenotype, and Function

(2015) Elizabeth C. Rosser et al.   IMMUNITY

Microbiota regulate the ability of lung dendritic cells to induce IgA class-switch recombination and generate protective gastrointestinal immune responses

(2015) Darren Ruane et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antiviral B cell and T cell immunity in the lungs

(2015) Christopher Chiu et al.   NATURE IMMUNOLOGY

Interrelated role of cigarette smoking, oxidative stress, and immune response in COPD and corresponding treatments

(2014) Li Zuo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cigarette smoke-induced iBALT mediates macrophage activation in a B cell-dependent manner in COPD

(2014) Gerrit John-Schuster et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Polymeric Immunoglobulin Receptor Down-regulation in Chronic Obstructive Pulmonary Disease. Persistence in the Cultured Epithelium and Role of Transforming Growth Factor-β

(2014) Sophie T. Gohy et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Adenovirus-Specific IgG Maturation as a Surrogate Marker in Acute Exacerbations of COPD

(2014) Lucas Boeck et al.   CHEST

IL-17–induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs

(2014) Henrike Fleige et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Altered Gene Expression in Blood and Sputum in COPD Frequent Exacerbators in the ECLIPSE Cohort

(2014) Dave Singh et al.   PLoS One

Genetic deletion of IL-17A reduces cigarette smoke-induced inflammation and alveolar type II cell apoptosis

(2013) Ying Chang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

CXCL13 Production in B Cells via Toll-like Receptor/Lymphotoxin Receptor Signaling Is Involved in Lymphoid Neogenesis in Chronic Obstructive Pulmonary Disease

(2013) Eleni Litsiou et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Role of CXCL13 in Cigarette Smoke–induced Lymphoid Follicle Formation and Chronic Obstructive Pulmonary Disease

(2013) Ken R. Bracke et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Epigenetic regulation of inducible gene expression in the immune system

(2013) Pek Siew Lim et al.   IMMUNOLOGY

B-lymphocyte lineage cells and the respiratory system

(2013) Atsushi Kato et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Genome-wide association study of lung function phenotypes in a founder population

(2013) Tsung-Chieh Yao et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Innate B cell helpers reveal novel types of antibody responses

(2013) Carola G Vinuesa et al.   NATURE IMMUNOLOGY

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease

(2012) Jørgen Vestbo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Autoimmunity in chronic obstructive pulmonary disease: clinical and experimental evidence

(2012) Farrah Kheradmand et al.   Expert Review of Clinical Immunology

Memory B cells in the lung participate in protective humoral immune responses to pulmonary influenza virus reinfection

(2012) T. Onodera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antielastin B-cell and T-cell immunity in patients with chronic obstructive pulmonary disease

(2012) Manuela Rinaldi et al.   THORAX

Bronchial Secretory Immunoglobulin A Deficiency Correlates With Airway Inflammation and Progression of Chronic Obstructive Pulmonary Disease

(2011) Vasiliy V. Polosukhin et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Oxidative Stress–induced Antibodies to Carbonyl-modified Protein Correlate with Severity of Chronic Obstructive Pulmonary Disease

(2011) Paul A. Kirkham et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Most B cells in non-lymphoid tissues are naïve

(2011) Charlotte F Inman et al.   IMMUNOLOGY AND CELL BIOLOGY

IL-1α/IL-1R1 Expression in Chronic Obstructive Pulmonary Disease and Mechanistic Relevance to Smoke-Induced Neutrophilia in Mice

(2011) Fernando M. Botelho et al.   PLoS One

A Novel Insight into Adaptive Immunity in Chronic Obstructive Pulmonary Disease

(2010) Francesca Polverino et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Anti-Tissue Antibodies Are Related to Lung Function in Chronic Obstructive Pulmonary Disease

(2010) Belén Núñez et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Smoke exposure as a determinant of autoantibody titre in  1-antitrypsin deficiency and COPD

(2010) A. M. Wood et al.   EUROPEAN RESPIRATORY JOURNAL

Acute pulmonary inflammation is inhibited in CXCR3 knockout mice after short-term cigarette smoke exposure

(2009) Li Nie et al.   ACTA PHARMACOLOGICA SINICA

Anti–Proline-Glycine-Proline or Antielastin Autoantibodies Are Not Evident in Chronic Inflammatory Lung Disease

(2009) Catherine M. Greene et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

BAFF: a local and systemic target in autoimmune diseases

(2009) I. Moisini et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Role of lymphotoxin-  in cigarette smoke-induced inflammation and lymphoid neogenesis

(2009) T. Demoor et al.   EUROPEAN RESPIRATORY JOURNAL

Lymphoid follicles in (very) severe COPD: beneficial or harmful?

(2009) G. G. Brusselle et al.   EUROPEAN RESPIRATORY JOURNAL

Cytokines and Cytokine Profiles in Human Autoimmune Diseases and Animal Models of Autoimmunity

(2009) Manfred Kunz et al.   MEDIATORS OF INFLAMMATION

Rituximab therapy reduces activated B cells in both the peripheral blood and bone marrow of patients with rheumatoid arthritis: depletion of memory B cells correlates with clinical response

(2009) Magda Nakou et al.   ARTHRITIS RESEARCH & THERAPY

Recent Advances in the Genetics of Autoimmune Disease

(2008) Peter K. Gregersen et al.   Annual Review of Immunology

B lymphocytes: how they develop and function

(2008) T. W. LeBien et al.   BLOOD

Cytokine-producing B lymphocytes—key regulators of immunity

(2008) Frances E Lund   CURRENT OPINION IN IMMUNOLOGY

B-lymphocyte contributions to human autoimmune disease

(2008) Koichi Yanaba et al.   IMMUNOLOGICAL REVIEWS

The cytokine network in asthma and chronic obstructive pulmonary disease

(2008) Peter J. Barnes   JOURNAL OF CLINICAL INVESTIGATION

Molecular pathogenesis of emphysema

(2008) Laimute Taraseviciene-Stewart et al.   JOURNAL OF CLINICAL INVESTIGATION

Autoantibodies in Patients with Chronic Obstructive Pulmonary Disease

(2007) Carol A. Feghali-Bostwick et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE