Immune Activation in α1-Antitrypsin-Deficiency Emphysema. Beyond the Protease–Antiprotease Paradigm

The Circulating Proteinase Inhibitor  -1 Antitrypsin Regulates Neutrophil Degranulation and Autoimmunity

(2014) D. A. Bergin et al.   Science Translational Medicine

The Lung Microbiome and Viral-induced Exacerbations of Chronic Obstructive Pulmonary Disease: New Observations, Novel Approaches

(2013) Robert P. Dickson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

α 1 -Antitrypsin Deficiency

(2013) Robert A. Stockley   CHEST

The Lung Tissue Microbiome in Chronic Obstructive Pulmonary Disease

(2012) Marc A. Sze et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Alpha-1 Antitrypsin: A Potent Anti-Inflammatory and Potential Novel Therapeutic Agent

(2012) David A. Bergin et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Clinical phenotypes of Italian and Spanish patients with α1-antitrypsin deficiency

(2012) Barbara Piras et al.   EUROPEAN RESPIRATORY JOURNAL

The Missing Link between Smoking and COPD Autoreactivity?

(2011) Steven R. Duncan   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Inhibition of IL-32 activation by  -1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model

(2011) A. M. Marcondes et al.   BLOOD

Evasion of COPD in smokers: at what price?

(2011) Manuel G. Cosio et al.   EUROPEAN RESPIRATORY JOURNAL

Analysis of the Lung Microbiome in the “Healthy” Smoker and in COPD

(2011) John R. Erb-Downward et al.   PLoS One

The discovery of α1-antitrypsin and its role in health and disease

(2011) Sabina M. Janciauskiene et al.   RESPIRATORY MEDICINE

Chronic Cigarette Smoke Exposure Generates Pathogenic T Cells Capable of Driving COPD-like Disease in Rag2−/−Mice

(2010) Gregory T. Motz et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

An Official Research Policy Statement of the American Thoracic Society/European Respiratory Society: Standards for Quantitative Assessment of Lung Structure

(2010) Connie C. W. Hsia et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Novel Insight into Adaptive Immunity in Chronic Obstructive Pulmonary Disease

(2010) Francesca Polverino et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Evidence for Unfolded Protein Response Activation in Monocytes from Individuals with  -1 Antitrypsin Deficiency

(2010) T. P. Carroll et al.   JOURNAL OF IMMUNOLOGY

Phenotypic Differences in Alpha 1 Antitrypsin-Deficient Sibling Pairs May Relate to Genetic Variation

(2009) Alice M. Wood et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

Immunologic Aspects of Chronic Obstructive Pulmonary Disease

(2009) Manuel G. Cosio et al.   NEW ENGLAND JOURNAL OF MEDICINE

IL-32, a Novel Proinflammatory Cytokine in Chronic Obstructive Pulmonary Disease

(2008) Fiorella Calabrese et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Autoantibodies in Patients with Chronic Obstructive Pulmonary Disease

(2007) Carol A. Feghali-Bostwick et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE