A TOR-YAK1 signaling axis controls cell cycle, meristem activity and plant growth in Arabidopsis

Reciprocal Regulation of the TOR Kinase and ABA Receptor Balances Plant Growth and Stress Response

(2018) Pengcheng Wang et al.   MOLECULAR CELL

AnnAt1 and AnnAt2 function in post-phloem sugar transport in root tips to affect primary root growth

(2018) Jing Wang et al.   PLANT PHYSIOLOGY

Plant dual-specificity tyrosine phosphorylation-regulated kinase optimizes light-regulated growth and development in Arabidopsis

(2017) Wen-Yu Huang et al.   PLANT CELL AND ENVIRONMENT

Regulatory-associated protein of TOR (RAPTOR) alters the hormonal and metabolic composition of Arabidopsis seeds, controlling seed morphology, viability and germination potential

(2017) Mohamed A. Salem et al.   PLANT JOURNAL

Differential TOR activation and cell proliferation inArabidopsisroot and shoot apexes

(2017) Xiaojuan Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation

(2017) Coline Balzergue et al.   Nature Communications

The inhibition of TOR in the model diatom Phaeodactylum tricornutum promotes a get-fat growth regime

(2017) Laura Prioretti et al.   Algal Research-Biomass Biofuels and Bioproducts

TOR-Dependent and -Independent Pathways Regulate Autophagy in Arabidopsis thaliana

(2017) Yunting Pu et al.   Frontiers in Plant Science

Ectopic expression of Arabidopsis Target of Rapamycin (AtTOR) improves water-use efficiency and yield potential in rice

(2017) Achala Bakshi et al.   Scientific Reports

TOR Signaling Promotes Accumulation of BZR1 to Balance Growth with Carbon Availability in Arabidopsis

(2016) Zhenzhen Zhang et al.   CURRENT BIOLOGY

Minibrain drives the Dacapo-dependent cell cycle exit of neurons in theDrosophilabrain by promotingasenseandprosperoexpression

(2016) Mirja N. Shaikh et al.   DEVELOPMENT

Arabidopsis YAK1 regulates abscisic acid response and drought resistance

(2016) Dongjin Kim et al.   FEBS LETTERS

Integration of light and metabolic signals for stem cell activation at the shoot apical meristem

(2016) Anne Pfeiffer et al.   eLife

The Arabidopsis TOR Kinase Specifically Regulates the Expression of Nuclear Genes Coding for Plastidic Ribosomal Proteins and the Phosphorylation of the Cytosolic Ribosomal Protein S6

(2016) Thomas Dobrenel et al.   Frontiers in Plant Science

Mutations in the Arabidopsis Lst8 and Raptor genes encoding partners of the TOR complex, or inhibition of TOR activity decrease abscisic acid (ABA) synthesis

(2015) Alena Kravchenko et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Arabidopsis Yak1 protein (AtYak1) is a dual specificity protein kinase

(2015) Dongjin Kim et al.   FEBS LETTERS

Spatial Regulation of Root Growth: Placing the Plant TOR Pathway in a Developmental Perspective

(2015) Adam Barrada et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CYCD3 D-type cyclins regulate cambial cell proliferation and secondary growth inArabidopsis

(2015) Carl Collins et al.   JOURNAL OF EXPERIMENTAL BOTANY

Plant hormone cross-talk: the pivot of root growth

(2015) Elena Pacifici et al.   JOURNAL OF EXPERIMENTAL BOTANY

DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3

(2015) Benjamin J. Thompson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Potyviruses differ in their requirement for TOR signalling

(2015) Laurence Ouibrahim et al.   JOURNAL OF GENERAL VIROLOGY

Stable Phenotypic Changes of the Host T Cells Are Essential to the Long-Term Stability of Latent HIV-1 Infection

(2015) Lillian Seu et al.   JOURNAL OF VIROLOGY

A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication

(2015) Peng Wang et al.   NATURE MEDICINE

Functional Conservation in the SIAMESE-RELATED Family of Cyclin-Dependent Kinase Inhibitors in Land Plants

(2015) Narender Kumar et al.   PLANT CELL

Differential Roles of Two Homologous Cyclin-Dependent Kinase Inhibitor Genes in Regulating Cell Cycle and Innate Immunity in Arabidopsis

(2015) Safae Hamdoun et al.   PLANT PHYSIOLOGY

Algal Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase, Triacylglycerol Accumulation Regulator1, Regulates Accumulation of Triacylglycerol in Nitrogen or Sulfur Deficiency

(2015) Masataka Kajikawa et al.   PLANT PHYSIOLOGY

TOR-inhibitor insensitive-1 (TRIN1) regulates cotyledons greening in Arabidopsis

(2015) Linxuan Li et al.   Frontiers in Plant Science

Expression profiling and functional analysis reveals that TOR is a key player in regulating photosynthesis and phytohormone signaling pathways in Arabidopsis

(2015) Pan Dong et al.   Frontiers in Plant Science

DYRK1A-mediated Cyclin D1 Degradation in Neural Stem Cells Contributes to the Neurogenic Cortical Defects in Down Syndrome

(2015) Sònia Najas et al.   EBioMedicine

The Down syndrome-related protein kinase DYRK1A phosphorylates p27Kip1and Cyclin D1 and induces cell cycle exit and neuronal differentiation

(2014) Ulf Soppa et al.   CELL CYCLE

WOX5 Suppresses CYCLIN D Activity to Establish Quiescence at the Center of the Root Stem Cell Niche

(2014) Celine Forzani et al.   CURRENT BIOLOGY

Hormonal control of cell division and elongation along differentiation trajectories in roots

(2014) Hirotomo Takatsuka et al.   JOURNAL OF EXPERIMENTAL BOTANY

Overexpression of the PP2A regulatory subunit Tap46 leads to enhanced plant growth through stimulation of the TOR signalling pathway

(2014) Chang Sook Ahn et al.   JOURNAL OF EXPERIMENTAL BOTANY

FANCM-associated proteins MHF1 and MHF2, but not the other Fanconi anemia factors, limit meiotic crossovers

(2014) Chloe Girard et al.   NUCLEIC ACIDS RESEARCH

The Arabidopsis SIAMESE-RELATED Cyclin-Dependent Kinase Inhibitors SMR5 and SMR7 Regulate the DNA Damage Checkpoint in Response to Reactive Oxygen Species

(2014) D. Yi et al.   PLANT CELL

Collective judgment predicts disease-associated single nucleotide variants

(2013) Emidio Capriotti et al.   BMC GENOMICS

Endocycling in the path of plant development

(2013) Christian Breuer et al.   CURRENT OPINION IN PLANT BIOLOGY

ATP-competitive mTOR kinase inhibitors delay plant growth by triggering early differentiation of meristematic cells but no developmental patterning change

(2013) Marie-Hélène Montané et al.   JOURNAL OF EXPERIMENTAL BOTANY

Glucose–TOR signalling reprograms the transcriptome and activates meristems

(2013) Yan Xiong et al.   NATURE

Identification of Arabidopsis Meiotic Cyclins Reveals Functional Diversification among Plant Cyclin Genes

(2013) Petra Bulankova et al.   PLoS Genetics

Control of the Plant Cell Cycle by Developmental and Environmental Cues

(2012) S. Komaki et al.   PLANT AND CELL PHYSIOLOGY

Mutations in the Arabidopsis Homolog of LST8/G L, a Partner of the Target of Rapamycin Kinase, Impair Plant Growth, Flowering, and Metabolic Adaptation to Long Days

(2012) M. Moreau et al.   PLANT CELL

Target of Rapamycin Signaling Regulates Metabolism, Growth, and Life Span in Arabidopsis

(2012) M. Ren et al.   PLANT CELL

Systemic analysis of inducible target of rapamycin mutants reveal a general metabolic switch controlling growth inArabidopsis thaliana

(2012) Camila Caldana et al.   PLANT JOURNAL

Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling

(2011) B. Hammerle et al.   DEVELOPMENT

DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly

(2011) L. Litovchick et al.   GENES & DEVELOPMENT

Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control

(2011) Robbie Loewith et al.   GENETICS

Rapamycin and Glucose-Target of Rapamycin (TOR) Protein Signaling in Plants

(2011) Yan Xiong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolution of the TOR Pathway

(2011) Teunis J. P. van Dam et al.   JOURNAL OF MOLECULAR EVOLUTION

The PP2A Regulatory Subunit Tap46, a Component of the TOR Signaling Pathway, Modulates Growth and Metabolism in Plants

(2011) Chang Sook Ahn et al.   PLANT CELL

Molecular control and function of endoreplication in development and physiology

(2011) Lieven De Veylder et al.   TRENDS IN PLANT SCIENCE

Beyond Rapalog Therapy: Preclinical Pharmacology and Antitumor Activity of WYE-125132, an ATP-Competitive and Specific Inhibitor of mTORC1 and mTORC2

(2010) K. Yu et al.   CANCER RESEARCH

DYRK family of protein kinases: evolutionary relationships, biochemical properties, and functional roles

(2010) Sergi Aranda et al.   FASEB JOURNAL

Activation, regulation, and inhibition of DYRK1A

(2010) Walter Becker et al.   FEBS Journal

Antagonistic Interactions Between the cAMP-Dependent Protein Kinase and Tor Signaling Pathways Modulate Cell Growth in Saccharomyces cerevisiae

(2010) V. Ramachandran et al.   GENETICS

Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana

(2010) Jelle Van Leene et al.   Molecular Systems Biology

Spatiotemporal regulation of cell-cycle genes by SHORTROOT links patterning and growth

(2010) R. Sozzani et al.   NATURE

The TOR Pathway Modulates the Structure of Cell Walls inArabidopsis

(2010) Ruth-Maria Leiber et al.   PLANT CELL

Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A

(2010) Yasushi Ogawa et al.   Nature Communications

AZD8055 Is a Potent, Selective, and Orally Bioavailable ATP-Competitive Mammalian Target of Rapamycin Kinase Inhibitor with In vitro and In vivo Antitumor Activity

(2009) C. M. Chresta et al.   CANCER RESEARCH

CDKB1;1 Forms a Functional Complex with CYCA2;3 to Suppress Endocycle Onset

(2009) V. Boudolf et al.   PLANT PHYSIOLOGY

APC/CCCS52Acomplexes control meristem maintenance in theArabidopsisroot

(2009) Marleen Vanstraelen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Yak1 Kinase Is Involved in the Initiation and Maintenance of Hyphal Growth in Candida albicans

(2008) Sophie Goyard et al.   MOLECULAR BIOLOGY OF THE CELL