The meiotic-specific Mek1 kinase in budding yeast regulates interhomolog recombination and coordinates meiotic progression with double-strand break repair

Genetic interactions between the chromosome axis-associated protein Hop1 and homologous recombination determinants in Schizosaccharomyces pombe

(2018) Simon David Brown et al.   CURRENT GENETICS

The PHD finger protein Spp1 has distinct functions in the Set1 and the meiotic DSB formation complexes

(2018) Céline Adam et al.   PLoS Genetics

Mek1 coordinates meiotic progression with DNA break repair by directly phosphorylating and inhibiting the yeast pachytene exit regulator Ndt80

(2018) Xiangyu Chen et al.   PLoS Genetics

Coordination of Double Strand Break Repair and Meiotic Progression in Yeast by a Mek1-Ndt80 Negative Feedback Loop

(2017) Evelyn Prugar et al.   GENETICS

Conformational dynamics of the Hop1 HORMA domain reveal a common mechanism with the spindle checkpoint protein Mad2

(2017) Alan M V West et al.   NUCLEIC ACIDS RESEARCH

Coordination of Double Strand Break Repair and Meiotic Progression in Yeast by a Mek1-Ndt80 Negative Feedback Loop

(2017) Evelyn Prugar et al.   GENETICS

Identification of Putative Mek1 Substrates during Meiosis in Saccharomyces cerevisiae Using Quantitative Phosphoproteomics

(2016) Raymond T. Suhandynata et al.   PLoS One

Chromosome Synapsis Alleviates Mek1-Dependent Suppression of Meiotic DNA Repair

(2016) Vijayalakshmi V. Subramanian et al.   PLOS BIOLOGY

Mek1 Down Regulates Rad51 Activity during Yeast Meiosis by Phosphorylation of Hed1

(2016) Tracy L. Callender et al.   PLoS Genetics

Sequestration of mRNAs Modulates the Timing of Translation during Meiosis in Budding Yeast

(2015) Liang Jin et al.   MOLECULAR AND CELLULAR BIOLOGY

Top3-Rmi1 DNA Single-Strand Decatenase Is Integral to the Formation and Resolution of Meiotic Recombination Intermediates

(2015) Hardeep Kaur et al.   MOLECULAR CELL

Pervasive and Essential Roles of the Top3-Rmi1 Decatenase Orchestrate Recombination and Facilitate Chromosome Segregation in Meiosis

(2015) Shangming Tang et al.   MOLECULAR CELL

Gradual Implementation of the Meiotic Recombination Program via Checkpoint Pathways Controlled by Global DSB Levels

(2015) Neeraj Joshi et al.   MOLECULAR CELL

Phosphorylation of the Synaptonemal Complex Protein Zip1 Regulates the Crossover/Noncrossover Decision during Yeast Meiosis

(2015) Xiangyu Chen et al.   PLOS BIOLOGY

Small Rad51 and Dmc1 Complexes Often Co-occupy Both Ends of a Meiotic DNA Double Strand Break

(2015) M. Scott Brown et al.   PLoS Genetics

Self-Organization of Meiotic Recombination Initiation: General Principles and Molecular Pathways

(2014) Scott Keeney et al.   Annual Review of Genetics

DDK links replication and recombination in meiosis

(2014) Hajime Murakami et al.   CELL CYCLE

Homologue engagement controls meiotic DNA break number and distribution

(2014) Drew Thacker et al.   NATURE

The Meiotic Checkpoint Network: Step-by-Step through Meiotic Prophase

(2014) V. V. Subramanian et al.   Cold Spring Harbor Perspectives in Biology

Down-Regulation of Rad51 Activity during Meiosis in Yeast Prevents Competition with Dmc1 for Repair of Double-Strand Breaks

(2014) Yan Liu et al.   PLoS Genetics

Meiotic and Mitotic Recombination in Meiosis

(2013) K. P. Kohl et al.   GENETICS

The Logic and Mechanism of Homologous Recombination Partner Choice

(2013) Soogil Hong et al.   MOLECULAR CELL

Positive regulation of meiotic DNA double-strand break formation by activation of the DNA damage checkpoint kinase Mec1(ATR)

(2013) S. Gray et al.   Open Biology

Meiotic Crossover Control by Concerted Action of Rad51-Dmc1 in Homolog Template Bias and Robust Homeostatic Regulation

(2013) Jessica P. Lao et al.   PLoS Genetics

Meiotic Prophase Requires Proteolysis of M Phase Regulators Mediated by the Meiosis-Specific APC/CAma1

(2012) Elwy Okaz et al.   CELL

The Sum1/Ndt80 Transcriptional Switch and Commitment to Meiosis in Saccharomyces cerevisiae

(2012) E. Winter   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

BLM Helicase Ortholog Sgs1 Is a Central Regulator of Meiotic Recombination Intermediate Metabolism

(2012) Arnaud De Muyt et al.   MOLECULAR CELL

Spp1, a Member of the Set1 Complex, Promotes Meiotic DSB Formation in Promoters by Tethering Histone H3K4 Methylation Sites to Chromosome Axes

(2012) Vérane Sommermeyer et al.   MOLECULAR CELL

Rad51 Is an Accessory Factor for Dmc1-Mediated Joint Molecule Formation During Meiosis

(2012) V. Cloud et al.   SCIENCE

The COMPASS Subunit Spp1 Links Histone Methylation to Initiation of Meiotic Recombination

(2012) L. Acquaviva et al.   SCIENCE

Regulatory Control of the Resolution of DNA Recombination Intermediates during Meiosis and Mitosis

(2011) Joao Matos et al.   CELL

Spo11-Accessory Proteins Link Double-Strand Break Sites to the Chromosome Axis in Early Meiotic Recombination

(2011) Silvia Panizza et al.   CELL

A Hierarchical Combination of Factors Shapes the Genome-wide Topography of Yeast Meiotic Recombination Initiation

(2011) Jing Pan et al.   CELL

Cdc7-Dbf4 Is a Gene-Specific Regulator of Meiotic Transcription in Yeast

(2011) H.-C. Lo et al.   MOLECULAR AND CELLULAR BIOLOGY

Nuclear localization of the meiosis-specific transcription factor Ndt80 is regulated by the pachytene checkpoint

(2011) Ying Wang et al.   MOLECULAR BIOLOGY OF THE CELL

Sister Cohesion and Structural Axis Components Mediate Homolog Bias of Meiotic Recombination

(2010) Keun P. Kim et al.   CELL

Mek1 Kinase Governs Outcomes of Meiotic Recombination and the Checkpoint Response

(2010) Hsin-Yen Wu et al.   CURRENT BIOLOGY

Mek1 Suppression of Meiotic Double-Strand Break Repair Is Specific to Sister Chromatids, Chromosome Autonomous and Independent of Rec8 Cohesin Complexes

(2010) T. L. Callender et al.   GENETICS

The Cdk1 and Ime2 Protein Kinases Trigger Exit from Meiotic Prophase in Saccharomyces cerevisiae by Inhibiting the Sum1 Transcriptional Repressor

(2010) M. E. Shin et al.   MOLECULAR AND CELLULAR BIOLOGY

Double Holliday junctions are intermediates of DNA break repair

(2010) Malgorzata Bzymek et al.   NATURE

Frequent and Efficient Use of the Sister Chromatid for DNA Double-Strand Break Repair during Budding Yeast Meiosis

(2010) Tamara Goldfarb et al.   PLOS BIOLOGY

Trying to Avoid Your Sister

(2010) Jessica P. Lao et al.   PLOS BIOLOGY

The Ime2 Protein Kinase Enhances the Disassociation of the Sum1 Repressor from Middle Meiotic Promoters

(2009) N. T. Ahmed et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of Meiotic Recombination via Mek1-Mediated Rad54 Phosphorylation

(2009) Hengyao Niu et al.   MOLECULAR CELL

Meiosis I Is Established through Division-Specific Translational Control of a Cyclin

(2008) Thomas M. Carlile et al.   CELL

Phosphorylation of the Axial Element Protein Hop1 by Mec1/Tel1 Ensures Meiotic Interhomolog Recombination

(2008) Jesús A. Carballo et al.   CELL

Cdc7-dependent phosphorylation of Mer2 facilitates initiation of yeast meiotic recombination

(2008) H. Sasanuma et al.   GENES & DEVELOPMENT

Polo-like kinase Cdc5 drives exit from pachytene during budding yeast meiosis

(2008) A. Sourirajan et al.   GENES & DEVELOPMENT

Cdc28-Clb5 (CDK-S) and Cdc7-Dbf4 (DDK) collaborate to initiate meiotic recombination in yeast

(2008) L. Wan et al.   GENES & DEVELOPMENT

Hed1 regulates Rad51-mediated recombination via a novel mechanism

(2008) V. Busygina et al.   GENES & DEVELOPMENT

The C-terminal Region of the Meiosis-specific Protein Kinase Ime2 Mediates Protein Instability and is Required for Normal Spore Formation in Budding Yeast

(2008) Fatih Sari et al.   JOURNAL OF MOLECULAR BIOLOGY

Rad52 Promotes Postinvasion Steps of Meiotic Double-Strand-Break Repair

(2008) Jessica P. Lao et al.   MOLECULAR CELL