Conformational dynamics of the Hop1 HORMA domain reveal a common mechanism with the spindle checkpoint protein Mad2

Basis of catalytic assembly of the mitotic checkpoint complex

(2017) Alex C. Faesen et al.   NATURE

The Pch2 AAA+ ATPase promotes phosphorylation of the Hop1 meiotic checkpoint adaptor in response to synaptonemal complex defects

(2016) Esther Herruzo et al.   NUCLEIC ACIDS RESEARCH

TRIP13 Regulates Both the Activation and Inactivation of the Spindle-Assembly Checkpoint

(2016) Hoi Tang Ma et al.   Cell Reports

Chromosome Synapsis Alleviates Mek1-Dependent Suppression of Meiotic DNA Repair

(2016) Vijayalakshmi V. Subramanian et al.   PLOS BIOLOGY

The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics

(2015) Andrea Musacchio   CURRENT BIOLOGY

The multifaceted roles of the HORMA domain in cellular signaling

(2015) Scott C. Rosenberg et al.   JOURNAL OF CELL BIOLOGY

Structure of an intermediate conformer of the spindle checkpoint protein Mad2

(2015) Mayuko Hara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mode of interaction of TRIP13 AAA-ATPase with the Mad2-binding protein p31comet and with mitotic checkpoint complexes

(2015) Shirly Miniowitz-Shemtov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recombination, Pairing, and Synapsis of Homologs during Meiosis

(2015) Denise Zickler et al.   Cold Spring Harbor Perspectives in Biology

Arabidopsis PCH2 Mediates Meiotic Chromosome Remodeling and Maturation of Crossovers

(2015) Christophe Lambing et al.   PLoS Genetics

Essential and Checkpoint Functions of Budding Yeast ATM and ATR during Meiotic Prophase Are Facilitated by Differential Phosphorylation of a Meiotic Adaptor Protein, Hop1

(2015) Ana Penedos et al.   PLoS One

Temporospatial Coordination of Meiotic DNA Replication and Recombination via DDK Recruitment to Replisomes

(2014) Hajime Murakami et al.   CELL

The Chromosome Axis Controls Meiotic Events through a Hierarchical Assembly of HORMA Domain Proteins

(2014) Yumi Kim et al.   DEVELOPMENTAL CELL

A non-sister act: Recombination template choice during meiosis

(2014) Neil Humphryes et al.   EXPERIMENTAL CELL RESEARCH

Thyroid Hormone Receptor Interacting Protein 13 (TRIP13) AAA-ATPase Is a Novel Mitotic Checkpoint-silencing Protein

(2014) Kexi Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Homologue engagement controls meiotic DNA break number and distribution

(2014) Drew Thacker et al.   NATURE

Disassembly of mitotic checkpoint complexes by the joint action of the AAA-ATPase TRIP13 and p31comet

(2014) E. Eytan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

N-Terminal Disordered Domain of Saccharomyces cerevisiae Hop1 Protein Is Dispensable for DNA Binding, Bridging, and Synapsis of Double-Stranded DNA Molecules But Is Necessary for Spore Formation

(2013) Krishnendu Khan et al.   BIOCHEMISTRY

Panta rhei: The APC/C at steady state

(2013) Ivana Primorac et al.   JOURNAL OF CELL BIOLOGY

CENTRAL REGION COMPONENT1, a Novel Synaptonemal Complex Component, Is Essential for Meiotic Recombination Initiation in Rice

(2013) C. Miao et al.   PLANT CELL

Meiotic Crossover Control by Concerted Action of Rad51-Dmc1 in Homolog Template Bias and Robust Homeostatic Regulation

(2013) Jessica P. Lao et al.   PLoS Genetics

Identification of novel mitosis regulators through data mining with human centromere/kinetochore proteins as group queries

(2012) Aaron R Tipton et al.   BMC CELL BIOLOGY

The Spindle Assembly Checkpoint

(2012) Pablo Lara-Gonzalez et al.   CURRENT BIOLOGY

Structure of the mitotic checkpoint complex

(2012) William C. H. Chao et al.   NATURE

Mek1 stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during yeast meiosis

(2012) C.-N. Chuang et al.   NUCLEIC ACIDS RESEARCH

Spo11-Accessory Proteins Link Double-Strand Break Sites to the Chromosome Axis in Early Meiotic Recombination

(2011) Silvia Panizza et al.   CELL

p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit

(2011) F. G. Westhorpe et al.   JOURNAL OF CELL SCIENCE

p31comet promotes disassembly of the mitotic checkpoint complex in an ATP-dependent process

(2011) A. Teichner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Checkpoint mechanisms: the puppet masters of meiotic prophase

(2011) Amy J. MacQueen et al.   TRENDS IN CELL BIOLOGY

Sister Cohesion and Structural Axis Components Mediate Homolog Bias of Meiotic Recombination

(2010) Keun P. Kim et al.   CELL

Phosphorylation and the creation of interhomolog bias during meiosis in yeast

(2010) Nancy M. Hollingsworth   CELL CYCLE

Mouse TRIP13/PCH2 Is Required for Recombination and Normal Higher-Order Chromosome Structure during Meiosis

(2010) Ignasi Roig et al.   PLoS Genetics

A novel mammalian HORMA domain-containing protein, HORMAD1, preferentially associates with unsynapsed meiotic chromosomes

(2009) Tomoyuki Fukuda et al.   EXPERIMENTAL CELL RESEARCH

Rec8 Guides Canonical Spo11 Distribution along Yeast Meiotic Chromosomes

(2009) Kazuto Kugou et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of Meiotic Recombination via Mek1-Mediated Rad54 Phosphorylation

(2009) Hengyao Niu et al.   MOLECULAR CELL

The pch2Δ Mutation in Baker's Yeast Alters Meiotic Crossover Levels and Confers a Defect in Crossover Interference

(2009) Sarah Zanders et al.   PLoS Genetics

Pch2 Links Chromosome Axis Remodeling at Future Crossover Sites and Crossover Distribution during Yeast Meiosis

(2009) Neeraj Joshi et al.   PLoS Genetics

Mouse HORMAD1 and HORMAD2, Two Conserved Meiotic Chromosomal Proteins, Are Depleted from Synapsed Chromosome Axes with the Help of TRIP13 AAA-ATPase

(2009) Lukasz Wojtasz et al.   PLoS Genetics

Phosphorylation of the Axial Element Protein Hop1 by Mec1/Tel1 Ensures Meiotic Interhomolog Recombination

(2008) Jesús A. Carballo et al.   CELL

Cdc28-Clb5 (CDK-S) and Cdc7-Dbf4 (DDK) collaborate to initiate meiotic recombination in yeast

(2008) L. Wan et al.   GENES & DEVELOPMENT

Yeast Pch2 promotes domainal axis organization, timely recombination progression, and arrest of defective recombinosomes during meiosis

(2008) G. V. Borner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Metamorphosis: The Two-State Behavior of Mad2

(2008) Xuelian Luo et al.   STRUCTURE

Insights into Mad2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric Mad2 Dimer

(2008) Maojun Yang et al.   PLOS BIOLOGY