The peroxisome proliferator-activated receptors under epigenetic control in placental metabolism and fetal development

Epigenetics and Metabolism

(2015) S. T. Keating et al.   CIRCULATION RESEARCH

Maternal gestational diabetes is associated with genome-wide DNA methylation variation in placenta and cord blood of exposed offspring

(2015) Sarah Finer et al.   HUMAN MOLECULAR GENETICS

Maternal nutrition influences angiogenesis in the placenta through peroxisome proliferator activated receptors: A novel hypothesis

(2015) Akshaya Meher et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Reproductive performance: at the cross-road of genetics, technologies and environment

(2015) Daniel Vaiman   REPRODUCTION FERTILITY AND DEVELOPMENT

Placental fibroblast growth factor 21 is not altered in late-onset preeclampsia

(2015) Marloes Dekker Nitert et al.   Reproductive Biology and Endocrinology

Oxidative stress and altered lipid homeostasis in the programming of offspring fatty liver by maternal obesity

(2014) Maria Z. Alfaradhi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The Placental Exposome: Placental Determinants of Fetal Adiposity and Postnatal Body Composition

(2014) R.M. Lewis et al.   ANNALS OF NUTRITION AND METABOLISM

Transcriptional Coregulators: Fine-Tuning Metabolism

(2014) Laurent Mouchiroud et al.   Cell Metabolism

Pregnancy and Infants’ Outcome: Nutritional and Metabolic Implications

(2014) C. Berti et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Peroxisome proliferator-activated receptor ligands regulate lipid content, metabolism, and composition in fetal lungs of diabetic rats

(2014) M Kurtz et al.   JOURNAL OF ENDOCRINOLOGY

PPAR ligands improve impaired metabolic pathways in fetal hearts of diabetic rats

(2014) Melisa Kurtz et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

MicroRNA-518d regulates PPARα protein expression in the placentas of females with gestational diabetes mellitus

(2014) CHUN ZHAO et al.   Molecular Medicine Reports

Metabolic programming—knowns, unknowns and possibilities

(2014) Susan E. Ozanne   Nature Reviews Endocrinology

Early Developmental Conditioning of Later Health and Disease: Physiology or Pathophysiology?

(2014) M. A. Hanson et al.   PHYSIOLOGICAL REVIEWS

Variation of DNA methylation in candidate age-related targets on the mitochondrial-telomere axis in cord blood and placenta

(2014) B.G. Janssen et al.   PLACENTA

Roles of PPARγ/NF-κB Signaling Pathway in the Pathogenesis of Intrahepatic Cholestasis of Pregnancy

(2014) Yan Zhang et al.   PLoS One

Epigenetics and life-long consequences of an adverse nutritional and diabetic intrauterine environment

(2014) Nady El Hajj et al.   REPRODUCTION

The balancing act – PPAR-γ’s roles at the maternal-fetal interface

(2014) Leena Kadam et al.   Systems Biology in Reproductive Medicine

New concepts in DNA methylation

(2014) Albert Jeltsch et al.   TRENDS IN BIOCHEMICAL SCIENCES

Circadian rhythms, Wnt/beta-catenin pathway and PPAR alpha/gamma profiles in diseases with primary or secondary cardiac dysfunction

(2014) Yves Lecarpentier et al.   Frontiers in Physiology

Peri-conceptional obesogenic exposure induces sex-specific programming of disease susceptibilities in adult mouse offspring

(2013) M. Dahlhoff et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Variable promoter methylation contributes to differential expression of key genes in human placenta-derived venous and arterial endothelial cells

(2013) Jihoon E Joo et al.   BMC GENOMICS

Reprogramming of the Circadian Clock by Nutritional Challenge

(2013) Kristin L. Eckel-Mahan et al.   CELL

Nuclear Hormone Receptors and Female Reproduction

(2013) A. Pestka et al.   CURRENT MOLECULAR MEDICINE

Placental regulation of fetal nutrient supply

(2013) Elvira Larqué et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

The Biology of the Peroxisome Proliferator-activated Receptor System in the Female Reproductive Tract

(2013) Leandro Velez et al.   CURRENT PHARMACEUTICAL DESIGN

Gestational diabetes predicts the risk of childhood overweight and abdominal circumference independent of maternal obesity

(2013) I. Nehring et al.   DIABETIC MEDICINE

Reduced Expression of 11β-Hydroxysteroid Dehydrogenase Type 2 in Preeclamptic Placentas Is Associated With Decreased PPARγ but Increased PPARα Expression

(2013) Ping He et al.   ENDOCRINOLOGY

Gestational diabetes mellitus epigenetically affects genes predominantly involved in metabolic diseases

(2013) Stephanie-May Ruchat et al.   Epigenetics

Involvement of adipokines, AMPK, PI3K and the PPAR signaling pathways in ovarian follicle development and cancer

(2013) Jolle Dupont et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Peroxisome proliferator-activated receptor-gamma (PPARγ) is down regulated in trophoblast cells of gestational diabetes mellitus (GDM) and in trophoblast tumour cells BeWo in vitro after stimulation with PPARγ agonists

(2013) Julia Knabl et al.   JOURNAL OF PERINATAL MEDICINE

Homeobox genes and down-stream transcription factor PPARγ in normal and pathological human placental development

(2013) P. Murthi et al.   PLACENTA

Placental programming of chronic diseases, cancer and lifespan: A review

(2013) D.J.P. Barker et al.   PLACENTA

The human placenta methylome

(2013) D. I. Schroeder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global Methylation in the Placenta and Umbilical Cord Blood From Pregnancies With Maternal Gestational Diabetes, Preeclampsia, and Obesity

(2013) Yoko Nomura et al.   Reproductive Sciences

Modulation of the Transcriptional Activity of Peroxisome Proliferator-Activated Receptor Gamma by Protein-Protein Interactions and Post-Translational Modifications

(2013) Tae-Hyun Kim et al.   YONSEI MEDICAL JOURNAL

Small-Molecule Hormones: Molecular Mechanisms of Action

(2013) Monika Puzianowska-Kuznicka et al.   International Journal of Endocrinology

Expression and Function of PPARs in Placenta

(2013) Satoru Matsuda et al.   PPAR Research

Maternal obesity, gestational weight gain and diet as determinants of offspring long term health

(2012) Lucilla Poston   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

The role of nutrition on epigenetic modifications and their implications on health

(2012) Josep C. Jiménez-Chillarón et al.   BIOCHIMIE

Modulation of Fatty Acid Transport and Metabolism by Maternal Obesity in the Human Full-Term Placenta1

(2012) Evemie Dubé et al.   BIOLOGY OF REPRODUCTION

Metabolic Programming of MEST DNA Methylation by Intrauterine Exposure to Gestational Diabetes Mellitus

(2012) N. El Hajj et al.   DIABETES

Placental Expression of Peroxisome Proliferator-Activated Receptor γ (PPARγ): Relation to Placental and Fetal Growth

(2012) Marta Díaz et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Glucose as a fetal nutrient: dynamic regulation of several glucose transporter genes by DNA methylation in the human placenta across gestation

(2012) Boris Novakovic et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Peroxisome Proliferator-Activated Receptor  /  Cross Talks with E2F and Attenuates Mitosis in HRAS-Expressing Cells

(2012) B. Zhu et al.   MOLECULAR AND CELLULAR BIOLOGY

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Repeated Abortion Affects Subsequent Pregnancy Outcomes in BALB/c Mice

(2012) Fang Lv et al.   PLoS One

PPARs at the crossroads of lipid signaling and inflammation

(2012) Walter Wahli et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Folate and DNA Methylation: A Review of Molecular Mechanisms and the Evidence for Folate's Role

(2012) Krista S. Crider et al.   Advances in Nutrition

A Decrease in DKK1, a WNT Inhibitor, Contributes to Placental Lipid Accumulation in an Obesity-Prone Rat Model1

(2011) Rita S. Strakovsky et al.   BIOLOGY OF REPRODUCTION

Evidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental/stochastic factors

(2011) Boris Novakovic et al.   BMC GENOMICS

Cell specific patterns of methylation in the human placenta

(2011) Ariadna Grigoriu et al.   Epigenetics

Epigenetic codes of PPARγ in metabolic disease

(2011) Shigeki Sugii et al.   FEBS LETTERS

Protein and folic acid content in the maternal diet determine lipid metabolism and response to high-fat feeding in rat progeny in an age-dependent manner

(2011) Agata Chmurzynska et al.   Genes and Nutrition

PPARα agonists regulate lipid metabolism and nitric oxide production and prevent placental overgrowth in term placentas from diabetic rats

(2011) Nora Martínez et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Intrauterine Growth Restriction as a Potential Risk Factor for Disease Onset in Adulthood

(2011) A.A. Varvarigou   JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM

Intrauterine Growth Restriction and Developmental Programming of the Metabolic Syndrome: A Critical Appraisal

(2011) UTA NEITZKE et al.   MICROCIRCULATION

DNA methylation profile in human placental tissues

(2011) E. N. Tolmacheva et al.   MOLECULAR BIOLOGY

Gestation-dependent changes in human placental global DNA methylation levels

(2011) Preeti Chavan-Gautam et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Expression and localization of DLX3, PPARG and SP1 in bovine trophoblast during binucleated cell differentiation

(2011) S.A. Degrelle et al.   PLACENTA

Dissecting the First Transcriptional Divergence During Human Embryonic Development

(2011) Qiang Bai et al.   Stem Cell Reviews and Reports

Lipid-sensing nuclear receptors in the pathophysiology and treatment of the metabolic syndrome

(2011) Michele Vacca et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Disturbances in lipid metabolism in diabetic pregnancy – Are these the cause of the problem?

(2010) Emilio Herrera et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

SIRT1 Is a Novel Regulator of Key Pathways of Human Labor1

(2010) Martha Lappas et al.   BIOLOGY OF REPRODUCTION

hCG-Induced Down-Regulation of PPARγ and Liver X Receptors Promotes Periovulatory Progesterone Synthesis by Macaque Granulosa Cells

(2010) Muraly Puttabyatappa et al.   ENDOCRINOLOGY

PPARγ in Placental Angiogenesis

(2010) Karim Nadra et al.   ENDOCRINOLOGY

The early origins of chronic heart failure: impaired placental growth and initiation of insulin resistance in childhood

(2010) David J.P. Barker et al.   EUROPEAN JOURNAL OF HEART FAILURE

Review: Effects of PPAR activation in the placenta and the fetus: Implications in maternal diabetes

(2010) A. Jawerbaum et al.   PLACENTA

Coactivators in PPAR-Regulated Gene Expression

(2010) Navin Viswakarma et al.   PPAR Research

Feeding a protein-restricted diet during pregnancy induces altered epigenetic regulation of peroxisomal proliferator-activated receptor-α in the heart of the offspring

(2010) J. L. Slater-Jefferies et al.   Journal of Developmental Origins of Health and Disease

Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation

(2009) Aparna Purushotham et al.   Cell Metabolism

hGH-V gene expression and promoter activity under glucose and 5-azacytidine (5azaC) effects

(2009) Marina Maria de Jesús Romero-Prado et al.   GENE

How nuclear receptors tell time

(2009) Michèle Teboul et al.   JOURNAL OF APPLIED PHYSIOLOGY

SUMOylation of Human Peroxisome Proliferator-activated Receptor α Inhibits Its Trans-activity through the Recruitment of the Nuclear Corepressor NCoR

(2009) Benoit Pourcet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Placenta-specific Methylation of the Vitamin D 24-Hydroxylase Gene

(2009) Boris Novakovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparison of the Transport Characteristics of Bioactive Substances in IUGR and Normal Placentas

(2009) Elisa Keating et al.   PEDIATRIC RESEARCH

Expression of folate transporters in human placenta and implications for homocysteine metabolism

(2009) N. Solanky et al.   PLACENTA

PPARγ Regulates Trophoblast Proliferation and Promotes Labyrinthine Trilineage Differentiation

(2009) Mana M. Parast et al.   PLoS One

Preterm and infection-driven preterm labor: the role of peroxisome proliferator-activated receptors and retinoid X receptor

(2009) Sarah J Holdsworth-Carson et al.   REPRODUCTION

Epigenetics, DNA Methylation, and Chromatin Modifying Drugs

(2008) Moshe Szyf   Annual Review of Pharmacology and Toxicology

Maternal exposure to folic acid antagonists and placenta-mediated adverse pregnancy outcomes

(2008) S. W. Wen et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging

(2008) Philipp Oberdoerffer et al.   CELL

High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice

(2008) Helen N. Jones et al.   FASEB JOURNAL

Postnatal Catch-up Growth After Fetal Protein Restriction Programs Proliferation of Rat Preadipocytes

(2008) Vanesa V. Bol et al.   Obesity

Persistent epigenetic differences associated with prenatal exposure to famine in humans

(2008) B. T. Heijmans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peroxisome proliferator-activated receptor α activation regulates lipid metabolism in the feto-placental unit from diabetic rats

(2008) N Martínez et al.   REPRODUCTION

Programmed Upregulation of Adipogenic Transcription Factors in Intrauterine Growth-Restricted Offspring

(2008) Mina Desai et al.   Reproductive Sciences

Profiling Gene Expression in Human Placentae of Different Gestational Ages: An OPRU* Network and UW SCOR Study

(2008) Andrei M. Mikheev et al.   Reproductive Sciences

PPAR Signaling in Placental Development and Function

(2007) Yaacov Barak et al.   PPAR Research