Coactivators in PPAR-Regulated Gene Expression

An RNA Interference Screen Identifies Metabolic Regulators NR1D1 and PBP as Novel Survival Factors for Breast Cancer Cells with the ERBB2 Signature

(2010) A. Kourtidis et al.   CANCER RESEARCH

MiR-205 silences MED1 in hypoxic primary human trophoblasts

(2010) Jean-Francois Mouillet et al.   FASEB JOURNAL

A muscle-specific knockout implicates nuclear receptor coactivator MED1 in the regulation of glucose and energy metabolism

(2010) W. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PPARδ-mediated p21/p27 induction via increased CREB-binding protein nuclear translocation in beraprost-induced antiproliferation of murine aortic smooth muscle cells

(2009) Yuh-Mou Sue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Peroxisome-proliferator-activated receptor-binding protein (PBP) is essential for the growth of active Notch4-immortalized mammary epithelial cells by activating SOX10 expression

(2009) Yiwei Tony Zhu et al.   BIOCHEMICAL JOURNAL

A pan-PPAR ligand induces hepatic fatty acid oxidation in PPARα−/− mice possibly through PGC-1 mediated PPARδ coactivation

(2009) Therese H. Røst et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Nuclear Receptor Coregulators in Cancer Biology

(2009) B. W. O'Malley et al.   CANCER RESEARCH

Transcription coactivator PBP/MED1-deficient hepatocytes are not susceptible to diethylnitrosamine-induced hepatocarcinogenesis in the mouse

(2009) K. Matsumoto et al.   CARCINOGENESIS

Who’s in charge? Nuclear receptor coactivator and corepressor function in brain and behavior

(2009) Marc J. Tetel et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Conditional Ablation of Mediator Subunit MED1 (MED1/PPARBP) Gene in Mouse Liver Attenuates Glucocorticoid Receptor Agonist Dexamethasone-Induced Hepatic Steatosis

(2009) YUZHI JIA et al.   GENE EXPRESSION

Down-regulation of the expression of RB18A/MED1, a cofactor of transcription, triggers strong tumorigenic phenotype of human melanoma cells

(2009) Jean de La Croix Ndong et al.   INTERNATIONAL JOURNAL OF CANCER

PRIP Promotes Tumor Formation through Enhancing Serum-responsive Factor-mediated FOS Expression

(2009) Yiwei Tony Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PPARδ Agonism Activates Fatty Acid Oxidation via PGC-1α but Does Not Increase Mitochondrial Gene Expression and Function

(2009) Sandra Kleiner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxisome Proliferator-Activated Receptor  /  (PPAR / ) but Not PPAR  Serves as a Plasma Free Fatty Acid Sensor in Liver

(2009) L. M. Sanderson et al.   MOLECULAR AND CELLULAR BIOLOGY

The PPARγ2 A/B-Domain Plays a Gene-Specific Role in Transactivation and Cofactor Recruitment

(2009) Anne Bugge et al.   MOLECULAR ENDOCRINOLOGY

Role of Jhdm2a in regulating metabolic gene expression and obesity resistance

(2009) Keisuke Tateishi et al.   NATURE

THE ROLE OF ENDOGENOUS AND EXOGENOUS LIGANDS FOR THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA (PPAR-α) IN THE REGULATION OF INFLAMMATION IN MACROPHAGES

(2009) Concetta Crisafulli et al.   SHOCK

The transcriptional coactivator PGC-1α is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis

(2008) John J. Lehman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The RNA Helicase p68 Is a Novel Androgen Receptor Coactivator Involved in Splicing and Is Overexpressed in Prostate Cancer

(2008) E. L. Clark et al.   CANCER RESEARCH

Chlamydia pneumoniae induces macrophage-derived foam cell formation via PPAR α and PPAR γ-dependent pathways

(2008) Chun-li Mei et al.   CELL BIOLOGY INTERNATIONAL

Genome-wide Coactivation Analysis of PGC-1α Identifies BAF60a as a Regulator of Hepatic Lipid Metabolism

(2008) Siming Li et al.   Cell Metabolism

CARM1 promotes adipocyte differentiation by coactivating PPARγ

(2008) Neelu Yadav et al.   EMBO REPORTS

Structural and Biochemical Basis for the Binding Selectivity of Peroxisome Proliferator-activated Receptor γ to PGC-1α

(2008) Yong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Med1 Subunit of Transcriptional Mediator Plays a Central Role in Regulating CCAAT/Enhancer-binding Protein-β-driven Transcription in Response to Interferon-γ

(2008) Hui Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PPAR.ALPHA. and PPAR.DELTA. Transactivity and p300 Binding Activity Induced by Arachidonic Acid in Colorectal Cancer Cell Line Caco-2

(2008) Kazuki MOCHIZUKI et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

Novel Peroxisome Proliferator-Activated Receptor   Agonists Lower Low-Density Lipoprotein and Triglycerides, Raise High-Density Lipoprotein, and Synergistically Increase Cholesterol Excretion with a Liver X Receptor Agonist

(2008) R. Mukherjee et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

MED1 Phosphorylation Promotes Its Association with Mediator: Implications for Nuclear Receptor Signaling

(2008) M. Belakavadi et al.   MOLECULAR AND CELLULAR BIOLOGY

Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA

(2008) Vikas Chandra et al.   NATURE

Absence of the SRC-2 Coactivator Results in a Glycogenopathy Resembling Von Gierke's Disease

(2008) A. R. Chopra et al.   SCIENCE