GPR30-mediated estrogenic regulation of actin polymerization and spatial memory involves SRC-1 and PI3K-mTORC2 in the hippocampus of female mice

Nuclear and membrane estrogen receptor antagonists induce similar mTORC2 activation-reversible changes in synaptic protein expression and actin polymerization in the mouse hippocampus

(2018) Fang-Zhou Xing et al.   CNS Neuroscience & Therapeutics

Steroid Receptor Coactivator-1 Knockdown Decreases Synaptic Plasticity and Impairs Spatial Memory in the Hippocampus of Mice

(2018) Chen Bian et al.   NEUROSCIENCE

Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease

(2017) Eric Tönnies et al.   JOURNAL OF ALZHEIMERS DISEASE

Estrogen receptor alpha and beta regulate actin polymerization and spatial memory through an SRC-1/mTORC2-dependent pathway in the hippocampus of female mice

(2017) Yangang Zhao et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Letrozole regulates actin cytoskeleton polymerization dynamics in a SRC-1 dependent manner in the hippocampus of mice

(2017) Yangang Zhao et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Distinct effects of estrogen receptor antagonism on object recognition and spatial memory consolidation in ovariectomized mice

(2017) Jaekyoon Kim et al.   PSYCHONEUROENDOCRINOLOGY

Rapid effects of dorsal hippocampal G-protein coupled estrogen receptor on learning in female mice

(2017) Jennifer Lymer et al.   PSYCHONEUROENDOCRINOLOGY

G-1 exerts neuroprotective effects through G protein-coupled estrogen receptor 1 following spinal cord injury in mice

(2016) Q. Cheng et al.   BIOSCIENCE REPORTS

mTORC1–S6K1 inhibition or mTORC2 activation improves hippocampal synaptic plasticity and learning in Angelman syndrome mice

(2016) Jiandong Sun et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Organization and dynamics of the actin cytoskeleton during dendritic spine morphological remodeling

(2016) Anaël Chazeau et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

RhoGTPases Spread the Word for Synaptic Crosstalk

(2016) Joseph G. Duman et al.   DEVELOPMENTAL CELL

Estrogen Receptor-Selective Agonists Modulate Learning in Female Rats in a Dose- and Task-Specific Manner

(2016) Samantha L. Pisani et al.   ENDOCRINOLOGY

17 -Estradiol and Agonism of G-protein-Coupled Estrogen Receptor Enhance Hippocampal Memory via Different Cell-Signaling Mechanisms

(2016) J. Kim et al.   JOURNAL OF NEUROSCIENCE

Ameliorative effect of membrane-associated estrogen receptor G protein coupled receptor 30 activation on object recognition memory in mouse models of Alzheimer's disease

(2016) Takashi Kubota et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Dose-dependent regulation of steroid receptor coactivator-1 and steroid receptors by testosterone propionate in the hippocampus of adult male mice

(2016) Linli Qiu et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Rho GTPase complementation underlies BDNF-dependent homo- and heterosynaptic plasticity

(2016) Nathan G. Hedrick et al.   NATURE

Drebrin A regulates hippocampal LTP and hippocampus-dependent fear learning in adult mice

(2016) N. Kojima et al.   NEUROSCIENCE

PI3K/Akt Activated by GPR30 and Src Regulates 17β-Estradiol-Induced Cultured Immature Boar Sertoli Cells Proliferation

(2016) Wei-Rong Yang et al.   Reproductive Sciences

GPR30 disrupts the balance of GABAergic and glutamatergic transmission in the spinal cord driving to the development of bone cancer pain

(2016) Jie Luo et al.   Oncotarget

Hippocampal Dendritic Spines Are Segregated Depending on Their Actin Polymerization

(2016) Nuria Domínguez-Iturza et al.   NEURAL PLASTICITY

The Involvement of Neuron-Specific Factors in Dendritic Spinogenesis: Molecular Regulation and Association with Neurological Disorders

(2016) Hsiao-Tang Hu et al.   NEURAL PLASTICITY

Control of Dendritic Spine Morphological and Functional Plasticity by Small GTPases

(2016) Kevin M. Woolfrey et al.   NEURAL PLASTICITY

Contribution of estrogen receptor subtypes, ERα, ERβ, and GPER1 in rapid estradiol-mediated enhancement of hippocampal synaptic transmission in mice

(2015) Ashok Kumar et al.   HIPPOCAMPUS

A novel form of synaptic plasticity in field CA3 of hippocampus requires GPER1 activation and BDNF release

(2015) Victor Briz et al.   JOURNAL OF CELL BIOLOGY

G-Protein-Coupled Estrogen Receptor 1 Is Anatomically Positioned to Modulate Synaptic Plasticity in the Mouse Hippocampus

(2015) E. M. Waters et al.   JOURNAL OF NEUROSCIENCE

Steroid receptor coactivator-1 mediates letrozole induced downregulation of postsynaptic protein PSD-95 in the hippocampus of adult female rats

(2015) Mengying Liu et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

G-protein-coupled receptor 30-mediated antiapoptotic effect of estrogen on spinal motor neurons following injury and its underlying mechanisms

(2015) JINGYU CHEN et al.   Molecular Medicine Reports

Estrogen Effects on Cognitive and Synaptic Health Over the Lifecourse

(2015) Yuko Hara et al.   PHYSIOLOGICAL REVIEWS

Rapid effects of the G-protein coupled oestrogen receptor (GPER) on learning and dorsal hippocampus dendritic spines in female mice

(2015) Christopher Gabor et al.   PHYSIOLOGY & BEHAVIOR

Rapid increases in immature synapses parallel estrogen-induced hippocampal learning enhancements

(2015) Anna Phan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of the G protein-coupled estrogen receptor, but not estrogen receptor α or β, rapidly enhances social learning

(2015) Kelsy Sharice Jean Ervin et al.   PSYCHONEUROENDOCRINOLOGY

TORC2: a novel target for treating age-associated memory impairment

(2015) Jennifer L. Johnson et al.   Scientific Reports

Estrogens Induce Rapid Cytoskeleton Re-Organization in Human Dermal Fibroblasts via the Non-Classical Receptor GPR30

(2015) Julie Carnesecchi et al.   PLoS One

Estradiol and GPER Activation Differentially Affect Cell Proliferation but Not GPER Expression in the Hippocampus of Adult Female Rats

(2015) Paula Duarte-Guterman et al.   PLoS One

A framework to understand the variations of PSD-95 expression in brain aging and in Alzheimer's disease

(2014) Armand Savioz et al.   AGEING RESEARCH REVIEWS

Activation of G-protein-coupled receptor 30 is sufficient to enhance spatial recognition memory in ovariectomized rats

(2014) Wayne R. Hawley et al.   BEHAVIOURAL BRAIN RESEARCH

Bufalin Is a Potent Small-Molecule Inhibitor of the Steroid Receptor Coactivators SRC-3 and SRC-1

(2014) Y. Wang et al.   CANCER RESEARCH

Memory Impairment in Estrogen Receptor α Knockout Mice Through Accumulation of Amyloid-β Peptides

(2014) Chul Ju Hwang et al.   MOLECULAR NEUROBIOLOGY

Post-synaptic Density-95 (PSD-95) Binding Capacity of G-protein-coupled Receptor 30 (GPR30), an Estrogen Receptor That Can Be Identified in Hippocampal Dendritic Spines

(2013) Keith T. Akama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

G protein-coupled estrogen receptor is required for the neuritogenic mechanism of 17β-estradiol in developing hippocampal neurons

(2013) Isabel Ruiz-Palmero et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

mTORC2 controls actin polymerization required for consolidation of long-term memory

(2013) Wei Huang et al.   NATURE NEUROSCIENCE

GPR30 activation decreases anxiety in the open field test but not in the elevated plus maze test in female mice

(2013) Divya Anchan et al.   Brain and Behavior

Chronic treatment with a GPR30 antagonist impairs acquisition of a spatial learning task in young female rats

(2012) R. Hammond et al.   HORMONES AND BEHAVIOR

The G Protein–Coupled Receptor GPR30 Mediates the Nontranscriptional Effect of Estrogen on the Activation of PI3K/Akt Pathway in Endometrial Cancer Cells

(2012) Xin Ge et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Low Doses of 17β-Estradiol Rapidly Improve Learning and Increase Hippocampal Dendritic Spines

(2012) Anna Phan et al.   NEUROPSYCHOPHARMACOLOGY

Gonadectomy differentially regulates steroid receptor coactivator-1 and synaptic proteins in the hippocampus of adult female and male C57BL/6 mice

(2012) Chen Bian et al.   SYNAPSE

GPER1/GPR30 Activation Improves Neuronal Survival Following Global Cerebral Ischemia Induced by Cardiac Arrest in Mice

(2012) Y. Kosaka et al.   Translational Stroke Research

Alterations of steroid receptor coactivator-1 (SRC-1) immunoreactivities in specific brain regions of young and middle-aged female Sprague–Dawley rats

(2011) Dongmei Zhang et al.   BRAIN RESEARCH

Expression of Steroid Receptor Coactivator-1 Was Regulated by Postnatal Development but Not Ovariectomy in the Hippocampus of Rats

(2011) Dongmei Zhang et al.   DEVELOPMENTAL NEUROSCIENCE

BDNF-Induced Increase of PSD-95 in Dendritic Spines Requires Dynamic Microtubule Invasions

(2011) X. Hu et al.   JOURNAL OF NEUROSCIENCE

Estrogen receptor alpha and G-protein coupled receptor 30 mediate the neuroprotective effects of 17β-estradiol in novel murine hippocampal cell models

(2010) S. Gingerich et al.   NEUROSCIENCE

Developmental Profile and Subcellular Localization of The Non-genomic Membranous Estrogen Receptor GPR30 in The Hippocampus of Postnatal Female Rats*

(2010) Cheng-Jun ZHAO et al.   PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS

Modulation of synaptic plasticity by brain estrogen in the hippocampus

(2009) Hideo Mukai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Chronic treatment with estrogen receptor agonists restores acquisition of a spatial learning task in young ovariectomized rats

(2009) R. Hammond et al.   HORMONES AND BEHAVIOR

Localisation of GPR30, a novel G protein-coupled oestrogen receptor, suggests multiple functions in rodent brain and peripheral tissues

(2009) Georgina G J Hazell et al.   JOURNAL OF ENDOCRINOLOGY

In vivo effects of a GPR30 antagonist

(2009) Megan K Dennis et al.   Nature Chemical Biology

Selective Estrogen Receptor Modulators Differentially Regulate Alzheimer-Like Changes in Female 3xTg-AD Mice

(2008) Jenna C. Carroll et al.   ENDOCRINOLOGY

Activation of estrogen receptor-β regulates hippocampal synaptic plasticity and improves memory

(2008) Feng Liu et al.   NATURE NEUROSCIENCE

Expression and intracellular distribution of the G protein-coupled receptor 30 in rat hippocampal formation

(2008) KenIchi Matsuda et al.   NEUROSCIENCE LETTERS

Rapid enhancement of two-step wiring plasticity by estrogen and NMDA receptor activity

(2008) D. P. Srivastava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA