Blockage of SLC31A1-dependent copper absorption increases pancreatic cancer cell autophagy to resist cell death

Influencing the Tumor Microenvironment: A Phase II Study of Copper Depletion Using Tetrathiomolybdate in Patients with Breast Cancer at High Risk for Recurrence and in Preclinical Models of Lung Metastases

(2016) Nancy Chan et al.   CLINICAL CANCER RESEARCH

Genetics and biology of pancreatic ductal adenocarcinoma

(2016) Haoqiang Ying et al.   GENES & DEVELOPMENT

Molecular imaging and therapy targeting copper metabolism in hepatocellular carcinoma

(2016) Jason Wachsmann   WORLD JOURNAL OF GASTROENTEROLOGY

Serum Concentrations of Selenium and Copper in Patients Diagnosed with Pancreatic Cancer

(2016) Marcin R. Lener et al.   Cancer Research and Treatment

Transcriptome analysis of copper homeostasis genes reveals coordinated upregulation ofSLC31A1,SCO1, andCOX11in colorectal cancer

(2016) Vincenza Barresi et al.   FEBS Open Bio

Mechanisms of Cancer Cell Dormancy--Another Hallmark of Cancer?

(2015) A. C. Yeh et al.   CANCER RESEARCH

Targeting copper in cancer therapy: ‘Copper That Cancer’

(2015) Delphine Denoyer et al.   Metallomics

Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine

(2015) Ming-Chen Yang et al.   Molecular Cancer

Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation

(2015) Jing Wang et al.   Nature Chemistry

Tetrathiomolybdate mediates cisplatin-induced p38 signaling and EGFR degradation and enhances response to cisplatin therapy in gynecologic cancers

(2015) Kyu Kwang Kim et al.   Scientific Reports

Copper depletion inhibits CoCl2-induced aggressive phenotype of MCF-7 cells via downregulation of HIF-1 and inhibition of Snail/Twist-mediated epithelial-mesenchymal transition

(2015) Shun Li et al.   Scientific Reports

Copper Signaling Axis as a Target for Prostate Cancer Therapeutics

(2014) R. Safi et al.   CANCER RESEARCH

Copper is required for oncogenic BRAF signalling and tumorigenesis

(2014) Donita C. Brady et al.   NATURE

Memo Is a Copper-Dependent Redox Protein with an Essential Role in Migration and Metastasis

(2014) G. MacDonald et al.   Science Signaling

Tetrathiomolybdate-associated copper depletion decreases circulating endothelial progenitor cells in women with breast cancer at high risk of relapse

(2013) S. Jain et al.   ANNALS OF ONCOLOGY

Non-hepatic tumors change the activity of genes encoding copper trafficking proteins in the liver

(2013) Polina S. Babich et al.   CANCER BIOLOGY & THERAPY

Bioavailable copper modulates oxidative phosphorylation and growth of tumors

(2013) S. Ishida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of the Human High-Affinity Copper Transporter in Copper Homeostasis Regulation and Cisplatin Sensitivity in Cancer Chemotherapy

(2012) M. T. Kuo et al.   CANCER RESEARCH

Lysyl Oxidase: From Basic Science to Future Cancer Treatment

(2012) Takeshi Nishioka et al.   CELL STRUCTURE AND FUNCTION

A Novel Role for Copper in Ras/Mitogen-Activated Protein Kinase Signaling

(2012) M. L. Turski et al.   MOLECULAR AND CELLULAR BIOLOGY

Enhancing Tumor-Specific Uptake of the Anticancer Drug Cisplatin with a Copper Chelator

(2010) Seiko Ishida et al.   CANCER CELL

Copper chelation in cancer therapy using tetrathiomolybdate: an evolving paradigm

(2009) Gazala Khan et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Elevated copper and oxidative stress in cancer cells as a target for cancer treatment

(2008) Anshul Gupte et al.   CANCER TREATMENT REVIEWS

COPPER AND ANGIOGENESIS: UNRAVELLING A RELATIONSHIP KEY TO CANCER PROGRESSION

(2008) Lydia Finney et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Mechanisms for copper acquisition, distribution and regulation

(2008) Byung-Eun Kim et al.   Nature Chemical Biology