LncRNA-ANRIL inhibits cell senescence of vascular smooth muscle cells by regulating miR-181a/Sirt1

miR-181a increases FoxO1 acetylation and promotes granulosa cell apoptosis via SIRT1 downregulation

(2017) Mei Zhang et al.   Cell Death & Disease

Protection of CD4 + T cells from hepatitis C virus infection-associated senescence via ΔNp63–miR-181a–Sirt1 pathway

(2016) Yun Zhou et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Endothelial cell senescence and thrombosis: Ageing clots

(2016) Magdalena L. Bochenek et al.   THROMBOSIS RESEARCH

Genistein-induced LKB1–AMPK activation inhibits senescence of VSMC through autophagy induction

(2016) Kyung Young Lee et al.   VASCULAR PHARMACOLOGY

DNA methylation at birth within the promoter of ANRIL predicts markers of cardiovascular risk at 9 years

(2016) Robert Murray et al.   Clinical Epigenetics

Suppression of centrosome protein TACC3 induces G1 arrest and cell death through activation of p38–p53–p21 stress signaling pathway

(2015) Thazhath V. Suhail et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

MicroRNAs and lncRNAs in senescence: A re-view

(2015) Oliver Bischof et al.   IUBMB LIFE

The mitochondrial lncRNA ASncmtRNA-2 is induced in aging and replicative senescence in Endothelial Cells

(2015) Valentina Bianchessi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The landscape of long noncoding RNAs in the human transcriptome

(2015) Matthew K Iyer et al.   NATURE GENETICS

Functional genomics of the CDKN2A/B locus in cardiovascular and metabolic disease: what have we learned from GWASs?

(2015) Sarah Anissa Hannou et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The lncRNA MIR31HG regulates p16INK4A expression to modulate senescence

(2015) Marta Montes et al.   Nature Communications

Tumor promoter-induced cellular senescence: cell cycle arrest followed by geroconversion

(2015) Olga V. Leontieva et al.   Oncotarget

miRNAs and lncRNAs in vascular injury and remodeling

(2014) XiaoWei Song et al.   Science China-Life Sciences

Small molecule SIRT1 activators for the treatment of aging and age-related diseases

(2014) Basil P. Hubbard et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Senescence-associated lncRNAs: senescence-associated long noncoding RNAs

(2013) Kotb Abdelmohsen et al.   AGING CELL

A comparison of replicative senescence and doxorubicin-induced premature senescence of vascular smooth muscle cells isolated from human aorta

(2013) Anna Bielak-Zmijewska et al.   BIOGERONTOLOGY

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

(2013) Tamara Tchkonia et al.   JOURNAL OF CLINICAL INVESTIGATION

The roles of senescence and telomere shortening in cardiovascular disease

(2013) Frej Fyhrquist et al.   Nature Reviews Cardiology

Alu Elements in ANRIL Non-Coding RNA at Chromosome 9p21 Modulate Atherogenic Cell Functions through Trans-Regulation of Gene Networks

(2013) Lesca M. Holdt et al.   PLoS Genetics

A role for mitochondrial oxidants in stress-induced premature senescence of human vascular smooth muscle cells

(2013) Yogita Mistry et al.   Redox Biology

Aging, Cellular Senescence, and Cancer

(2012) Judith Campisi   Annual Review of Physiology

CVD-associated non-coding RNA, ANRIL, modulates expression of atherogenic pathways in VSMC

(2012) Ada Congrains et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Downregulation of miR-181a upregulates sirtuin-1 (SIRT1) and improves hepatic insulin sensitivity

(2012) B. Zhou et al.   DIABETOLOGIA

58-kDa Microspherule Protein (MSP58) Is Novel Brahma-related Gene 1 (BRG1)-associated Protein That Modulates p53/p21 Senescence Pathway

(2012) Che-Chia Hsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice

(2012) Hongwei Yao et al.   JOURNAL OF CLINICAL INVESTIGATION

Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity

(2012) Guangjin Li et al.   NATURE MEDICINE

Quantitative Model of Cell Cycle Arrest and Cellular Senescence in Primary Human Fibroblasts

(2012) Sascha Schäuble et al.   PLoS One

The p53/p21WAF/CIP Pathway Mediates Oxidative Stress and Senescence in Dyskeratosis Congenita Cells with Telomerase Insufficiency

(2010) Erik R. Westin et al.   ANTIOXIDANTS & REDOX SIGNALING

ANRIL Expression Is Associated With Atherosclerosis Risk at Chromosome 9p21

(2010) Lesca M. Holdt et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression

(2010) Michael S. Cunnington et al.   PLoS Genetics

INK4/ARF Transcript Expression Is Associated with Chromosome 9p21 Variants Linked to Atherosclerosis

(2009) Yan Liu et al.   PLoS One

SIRT1 Overexpression Antagonizes Cellular Senescence with Activated ERK/S6k1 Signaling in Human Diploid Fibroblasts

(2008) Jing Huang et al.   PLoS One