Various Evolutionary Trajectories Lead to Loss of the Tobramycin-Potentiating Activity of the Quorum-Sensing Inhibitor Baicalin Hydrate in Burkholderia cenocepacia Biofilms

Elucidation of the mechanism behind the potentiating activity of baicalin against Burkholderia cenocepacia biofilms

(2018) Lisa Slachmuylders et al.   PLoS One

Evolutionary Mechanisms Shaping the Maintenance of Antibiotic Resistance

(2018) Paulo Durão et al.   TRENDS IN MICROBIOLOGY

Experimental Evolution as a High-Throughput Screen for Genetic Adaptations

(2018) Vaughn S. Cooper   mSphere

The Small RNA ncS35 Regulates Growth in Burkholderia cenocepacia J2315

(2018) Sanne Kiekens et al.   mSphere

Experimental Design, Population Dynamics, and Diversity in Microbial Experimental Evolution

(2018) Bram Van den Bergh et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Investigating the Mechanism of Action of Diketopiperazines Inhibitors of the Burkholderia cenocepacia Quorum Sensing Synthase CepI: A Site-Directed Mutagenesis Study

(2018) Silvia Buroni et al.   Frontiers in Pharmacology

The Role of Reactive Oxygen Species in Antibiotic-Mediated Killing of Bacteria

(2017) Heleen Van Acker et al.   TRENDS IN MICROBIOLOGY

Burkholderia cenocepacia Infections in Cystic Fibrosis Patients: Drug Resistance and Therapeutic Approaches

(2017) Viola C. Scoffone et al.   Frontiers in Microbiology

The Challenge of Overcoming Antibiotic Resistance: An Adjuvant Approach?

(2017) Roberta J. Melander et al.   ACS Infectious Diseases

Baicalin inhibits biofilm formation, attenuates the quorum sensing-controlled virulence and enhances Pseudomonas aeruginosa clearance in a mouse peritoneal implant infection model

(2017) Jing Luo et al.   PLoS One

Integrated roles of BclA and DD-carboxypeptidase 1 in Bradyrhizobium differentiation within NCR-producing and NCR-lacking root nodules

(2017) Quentin Barrière et al.   Scientific Reports

Antibacterial drug discovery in the resistance era

(2016) Eric D. Brown et al.   NATURE

CDD/SPARCLE: functional classification of proteins via subfamily domain architectures

(2016) Aron Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

Antibiotic Adjuvants: Rescuing Antibiotics from Resistance

(2016) Gerard D. Wright   TRENDS IN MICROBIOLOGY

Mechanisms of resistance to aminoglycoside antibiotics: overview and perspectives

(2016) Sylvie Garneau-Tsodikova et al.   MedChemComm

Discovery of new diketopiperazines inhibiting Burkholderia cenocepacia quorum sensing in vitro and in vivo

(2016) Viola C. Scoffone et al.   Scientific Reports

Candidate Essential Genes in Burkholderia cenocepacia J2315 Identified by Genome-Wide TraDIS

(2016) Yee-Chin Wong et al.   Frontiers in Microbiology

The Role of Reactive Oxygen Species in Antibiotic-Induced Cell Death in Burkholderia cepacia Complex Bacteria

(2016) Heleen Van Acker et al.   PLoS One

Genome-wide transcription start site profiling in biofilm-grown Burkholderia cenocepacia J2315

(2015) Andrea M. Sass et al.   BMC GENOMICS

Can resistance against quorum-sensing interference be selected?

(2015) Rodolfo García-Contreras et al.   ISME Journal

Bradyrhizobium BclA Is a Peptide Transporter Required for Bacterial Differentiation in Symbiosis with Aeschynomene Legumes

(2015) Ibtissem Guefrachi et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Antibiotic resistance breakers: can repurposed drugs fill the antibiotic discovery void?

(2015) David Brown   NATURE REVIEWS DRUG DISCOVERY

Competition Studies Confirm Two Major Barriers That Can Preclude the Spread of Resistance to Quorum-Sensing Inhibitors in Bacteria

(2014) Joseph P. Gerdt et al.   ACS Chemical Biology

Antibiotic Adjuvants: Diverse Strategies for Controlling Drug-Resistant Pathogens

(2014) Erin E. Gill et al.   Chemical Biology & Drug Design

Molecular mechanisms of antimicrobial tolerance and resistance in bacterial and fungal biofilms

(2014) Heleen Van Acker et al.   TRENDS IN MICROBIOLOGY

The unexpected discovery of a novel low-oxygen-activated locus for the anoxic persistence of Burkholderia cenocepacia

(2013) Andrea M Sass et al.   ISME Journal

Biofilm-Grown Burkholderia cepacia Complex Cells Survive Antibiotic Treatment by Avoiding Production of Reactive Oxygen Species

(2013) Heleen Van Acker et al.   PLoS One

A high-throughput screen for quorum-sensing inhibitors that target acyl-homoserine lactone synthases

(2013) Quin H. Christensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A vitamin B12 transporter in Mycobacterium tuberculosis

(2013) K. Gopinath et al.   Open Biology

Interference of bacterial cell-to-cell communication: A new concept of antimicrobial chemotherapy breaks antibiotic

(2013) Hidetada Hirakawa et al.   Frontiers in Microbiology

Antibiotic adjuvants: identification and clinical use

(2013) Patricia Bernal et al.   Microbial Biotechnology

Tangled bank of experimentally evolved Burkholderia biofilms reflects selection during chronic infections

(2012) C. C. Traverse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neglected but amazingly diverse type IVb pili

(2012) Nicolas Roux et al.   RESEARCH IN MICROBIOLOGY

Quorum Sensing Inhibitors Increase the Susceptibility of Bacterial Biofilms to Antibiotics In Vitro and In Vivo

(2011) Gilles Brackman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Quorum quenching quandary: resistance to antivirulence compounds

(2011) Toshinari Maeda et al.   ISME Journal

Acceleration of Emergence of Bacterial Antibiotic Resistance in Connected Microenvironments

(2011) Q. Zhang et al.   SCIENCE

The Sociomicrobiology of Antivirulence Drug Resistance: a Proof of Concept

(2011) B. Mellbye et al.   mBio

Efflux Pumps, OprD Porin, AmpC  -Lactamase, and Multiresistance in Pseudomonas aeruginosa Isolates from Cystic Fibrosis Patients

(2010) M. Tomas et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Social interactions in theBurkholderia cepaciacomplex: biofilms and quorum sensing

(2010) Tom Coenye   Future Microbiology

In vitro activity of temocillin against planktonic and sessile Burkholderia cepacia complex bacteria

(2010) Heleen Van Acker et al.   Journal of Cystic Fibrosis

Antibiotic resistance and its cost: is it possible to reverse resistance?

(2010) Dan I. Andersson et al.   NATURE REVIEWS MICROBIOLOGY

Can Bacteria Evolve Resistance to Quorum Sensing Disruption?

(2010) Tom Defoirdt et al.   PLoS Pathogens

The Burkholderia Genome Database: facilitating flexible queries and comparative analyses

(2008) G. L. Winsor et al.   BIOINFORMATICS

The Genome of Burkholderia cenocepacia J2315, an Epidemic Pathogen of Cystic Fibrosis Patients

(2008) M. T. G. Holden et al.   JOURNAL OF BACTERIOLOGY