Chemical and Ribosomal Synthesis of Topologically Controlled Bicyclic and Tricyclic Peptide Scaffolds Primed by Selenoether Formation

Designing macrocyclic disulfide-rich peptides for biotechnological applications

(2018) Conan K. Wang et al.   Nature Chemical Biology

Cyclization of peptides with two chemical bridges affords large scaffold diversities

(2018) Sangram S. Kale et al.   Nature Chemistry

Development and Application of Yeast and Phage Display of Diverse Lanthipeptides

(2018) Kenton J. Hetrick et al.   ACS Central Science

Phage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein

(2017) Johannes H. Urban et al.   Nature Communications

Accurate de novo design of hyperstable constrained peptides

(2016) Gaurav Bhardwaj et al.   NATURE

Expanding the amino acid repertoire of ribosomal polypeptide synthesis via the artificial division of codon boxes

(2016) Yoshihiko Iwane et al.   Nature Chemistry

Converting disulfide bridges in native peptides to stable methylene thioacetals

(2016) C. M. B. K. Kourra et al.   Chemical Science

Oxidative Deselenization of Selenocysteine: Applications for Programmed Ligation at Serine

(2015) Lara R. Malins et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Thiol-Ene Coupling Approach to Native Peptide Stapling and Macrocyclization

(2015) Yuanxiang Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diaminodiacid Bridges to Improve Folding and Tune the Bioactivity of Disulfide-Rich Peptides

(2015) Ye Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of fused tricyclic peptides using a reprogrammed translation system and chemical modification

(2015) Nasir Kato Bashiruddin et al.   BIOORGANIC CHEMISTRY

Orthogonal Cysteine–Penicillamine Disulfide Pairing for Directing the Oxidative Folding of Peptides

(2015) Yiwu Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Umpolung Approach for the Chemoselective Arylation of Selenocysteine in Unprotected Peptides

(2015) Daniel T. Cohen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Peptide Ligands Stabilized by Small Molecules

(2014) Shiyu Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery, Synthesis, and Structure–Activity Relationships of Conotoxins

(2014) Kalyana B. Akondi et al.   CHEMICAL REVIEWS

Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides

(2014) Shiyu Chen et al.   Nature Chemistry

Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain

(2014) Aline Dantas de Araujo et al.   Nature Communications

Diaminodiacid-Based Solid-Phase Synthesis of Peptide Disulfide Bond Mimics

(2013) Hong-Kui Cui et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multifaceted Roles of Disulfide Bonds. Peptides as Therapeutics

(2013) Miriam Góngora-Benítez et al.   CHEMICAL REVIEWS

A Perfluoroaryl-Cysteine SNAr Chemistry Approach to Unprotected Peptide Stapling

(2013) Alexander M. Spokoyny et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cyclization of Peptides by using Selenolanthionine Bridges

(2012) Aline Dantas de Araujo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The use of 2,2′-dithiobis(5-nitropyridine) (DTNP) for deprotection and diselenide formation in protected selenocysteine-containing peptides

(2012) Alayne L. Schroll et al.   JOURNAL OF PEPTIDE SCIENCE

In Vitro Selection of Highly Modified Cyclic Peptides That Act as Tight Binding Inhibitors

(2012) Yollete V. Guillen Schlippe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of α-Helical Calpain Probes by Mimicking a Natural Protein–Protein Interaction

(2012) Hyunil Jo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Twin disulfides for orthogonal disulfide pairing and the directed folding of multicyclic peptides

(2012) Chuanliu Wu et al.   Nature Chemistry

Selective thioether macrocyclization of peptides having the N-terminal 2-chloroacetyl group and competing two or three cysteine residues in translation

(2012) Kazuhiro Iwasaki et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Site-Specific pKa Determination of Selenocysteine Residues in Selenovasopressin by Using 77Se NMR Spectroscopy

(2011) Mehdi Mobli et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Natural Product-Like Macrocyclic N-Methyl-Peptide Inhibitors against a Ubiquitin Ligase Uncovered from a Ribosome-Expressed De Novo Library

(2011) Yusuke Yamagishi et al.   CHEMISTRY & BIOLOGY

Flexizymes for genetic code reprogramming

(2011) Yuki Goto et al.   Nature Protocols

Ribosomal synthesis of dehydrobutyrine- and methyllanthionine-containing peptides

(2009) Yuki Goto et al.   CHEMICAL COMMUNICATIONS

Phage-encoded combinatorial chemical libraries based on bicyclic peptides

(2009) Christian Heinis et al.   Nature Chemical Biology

Reprogramming the Translation Initiation for the Synthesis of Physiologically Stable Cyclic Peptides

(2008) Yuki Goto et al.   ACS Chemical Biology

Ribosomal Synthesis of Bicyclic Peptides via Two Orthogonal Inter-Side-Chain Reactions

(2008) Yusuke Sako et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Initiating translation with D-amino acids

(2008) Y. Goto et al.   RNA