A Thiol-Ene Coupling Approach to Native Peptide Stapling and Macrocyclization

Hydrocarbon Stapled Peptides as Modulators of Biological Function

(2015) Philipp M. Cromm et al.   ACS Chemical Biology

Peptide/Protein Stapling and Unstapling: Introduction of s-Tetrazine, Photochemical Release, and Regeneration of the Peptide/Protein

(2015) Stephen P. Brown et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cysteine-Selective Reactions for Antibody Conjugation

(2014) Pedro M. S. D. Cal et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Comparative α-Helicity of Cyclic Pentapeptides in Water

(2014) Aline D. de Araujo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress

(2014) Loren D. Walensky et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inhibiting Epidermal Growth Factor Receptor at a Distance

(2014) Julie K.-L. Sinclair et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functionalised staple linkages for modulating the cellular activity of stapled peptides

(2014) Yu Heng Lau et al.   Chemical Science

Direct Peptide Lipidation through Thiol-Ene Coupling Enables Rapid Synthesis and Evaluation of Self-Adjuvanting Vaccine Candidates

(2013) Tom H. Wright et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Perfluoroaryl-Cysteine SNAr Chemistry Approach to Unprotected Peptide Stapling

(2013) Alexander M. Spokoyny et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intramolecular bridges formed by photoswitchable click amino acids

(2012) Christian Hoppmann et al.   Beilstein Journal of Organic Chemistry

Development of α-Helical Calpain Probes by Mimicking a Natural Protein–Protein Interaction

(2012) Hyunil Jo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inhibition of oncogenic Wnt signaling through direct targeting of  -catenin

(2012) T. N. Grossmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetically encoded alkenyl–pyrrolysine analogues for thiol–ene reaction mediated site-specific protein labeling

(2012) Yiming Li et al.   Chemical Science

A Direct Method for Site-Specific Protein Acetylation

(2011) Fupeng Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Promoting peptide α-helix formation with dynamic covalent oxime side-chain cross-links

(2011) Conor M. Haney et al.   CHEMICAL COMMUNICATIONS

Synthesis of all-hydrocarbon stapled α-helical peptides by ring-closing olefin metathesis

(2011) Young-Woo Kim et al.   Nature Protocols

A Stapled p53 Helix Overcomes HDMX-Mediated Suppression of p53

(2010) Federico Bernal et al.   CANCER CELL

On-resin peptide macrocyclization using thiol–ene click chemistry

(2010) Alex A. Aimetti et al.   CHEMICAL COMMUNICATIONS

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A New Ligation Strategy for Peptide and Protein Glycosylation: Photoinduced Thiol-Ene Coupling

(2009) Alessandro Dondoni et al.   CHEMISTRY-A EUROPEAN JOURNAL

Direct inhibition of the NOTCH transcription factor complex

(2009) Raymond E. Moellering et al.   NATURE