Identification of Flavin Mononucleotide as a Cell-Active Artificial N 6 -Methyladenosine RNA Demethylase

Bioorthogonal Catalytic Activation of Platinum and Ruthenium Anticancer Complexes by FAD and Flavoproteins

(2018) Silvia Alonso-de Castro et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

RNA N6-methyladenosine modification in cancers: current status and perspectives

(2018) Xiaolan Deng et al.   CELL RESEARCH

Multi-Protein Dynamic Combinatorial Chemistry: A Novel Strategy that Leads to Simultaneous Discovery of Subfamily-Selective Inhibitors for Nucleic Acid Demethylases FTO and ALKBH3

(2018) Mohua Das et al.   Chemistry-An Asian Journal

Selective recognition of HIV RNA by dinuclear metallic ligands

(2018) Xuedong Li et al.   CHINESE CHEMICAL LETTERS

NMR analyses on N-hydroxymethylated nucleobases – implications for formaldehyde toxicity and nucleic acid demethylases

(2018) S. Shishodia et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Blue light induced reactive oxygen species from flavin mononucleotide and flavin adenine dinucleotide on lethality of HeLa cells

(2017) Ming-Yeh Yang et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

RNA Chemical Proteomics Reveals the N6-Methyladenosine (m6A)-Regulated Protein–RNA Interactome

(2017) A. Emilia Arguello et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective tumor cell death induced by irradiated riboflavin through recognizing DNA G–T mismatch

(2017) Yi Yuan et al.   NUCLEIC ACIDS RESEARCH

The chemistries and consequences of DNA and RNA methylation and demethylation

(2017) Franziska R. Traube et al.   RNA Biology

The RNA modification landscape in human disease

(2017) Nicky Jonkhout et al.   RNA

The RNA Modification N 6 -methyladenosine and Its Implications in Human Disease

(2017) Pedro J. Batista   GENOMICS PROTEOMICS & BIOINFORMATICS

Halogenase-Inspired Oxidative Chlorination Using Flavin Photocatalysis

(2016) Thea Hering et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Novel Inhibitor of the Obesity-Related Protein FTO

(2016) Yan Qiao et al.   BIOCHEMISTRY

ALKBHs-facilitated RNA modifications and de-modifications

(2016) Endalkachew A. Alemu et al.   DNA REPAIR

Rhein Inhibits AlkB Repair Enzymes and Sensitizes Cells to Methylated DNA Damage

(2016) Qi Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Flavin-Dependent Methylation of RNAs: Complex Chemistry for a Simple Modification

(2016) Djemel Hamdane et al.   JOURNAL OF MOLECULAR BIOLOGY

Fluorescence Monitoring of the Oxidative Repair of DNA Alkylation Damage by ALKBH3, a Prostate Cancer Marker

(2016) Andrew A. Beharry et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The emerging biology of RNA post-transcriptional modifications

(2016) Sigrid Nachtergaele et al.   RNA Biology

Recent advances in dynamic m6A RNA modification

(2016) Guangchao Cao et al.   Open Biology

CH Photooxygenation of Alkyl Benzenes Catalyzed by Riboflavin Tetraacetate and a Non-Heme Iron Catalyst

(2015) Bernd Mühldorf et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in mammalian model cells by CE with LED-induced fluorescence detection

(2015) Jens Hühner et al.   ELECTROPHORESIS

Identification of A Novel Small-Molecule Binding Site of the Fat Mass and Obesity Associated Protein (FTO)

(2015) Wu He et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein

(2015) Tianlu Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure and Thermodynamics of N6-Methyladenosine in RNA: A Spring-Loaded Base Modification

(2015) Caroline Roost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N 6-Hydroperoxymethyladenosine: a new intermediate of chemical oxidation of N6-methyladenosine mediated by bicarbonate-activated hydrogen peroxide

(2015) Jinjun Wu et al.   Chemical Science

Computations Reveal a Rich Mechanistic Variation of Demethylation of N-Methylated DNA/RNA Nucleotides by FTO

(2015) Binju Wang et al.   ACS Catalysis

Synthesis of a FTO Inhibitor with Anticonvulsant Activity

(2014) Guanqun Zheng et al.   ACS Chemical Neuroscience

Mechanism and Function of Oxidative Reversal of DNA and RNA Methylation

(2014) Li Shen et al.   Annual Review of Biochemistry

Emerging Roles of RNA Modification: m 6 A and U-Tail

(2014) Mihye Lee et al.   CELL

Riboflavin Interactions with Oxygen-A Survey from the Photochemical Perspective

(2014) Małgorzata Insińska-Rak et al.   CHEMISTRY-A EUROPEAN JOURNAL

Dynamic RNA modifications in disease

(2014) Arne Klungland et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Structures of Human ALKBH5 Demethylase Reveal a Unique Binding Mode for Specific Single-strandedN6-Methyladenosine RNA Demethylation

(2014) Chao Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic RNA Modifications in Posttranscriptional Regulation

(2014) Xiao Wang et al.   MOLECULAR CELL

Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5

(2014) Yue Huang et al.   NUCLEIC ACIDS RESEARCH

Deoxypolypeptides bind and cleave RNA

(2014) L. Cheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repair of methyl lesions in RNA by oxidative demethylation

(2014) Fei Ye et al.   MedChemComm

Identification of a Selective Polymerase Enables Detection of N6-Methyladenosine in RNA

(2013) Emily M. Harcourt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sprouts of RNA epigenetics

(2013) Guanqun Zheng et al.   RNA Biology

N6-methyl-adenosine modification in messenger and long non-coding RNA

(2013) Tao Pan   TRENDS IN BIOCHEMICAL SCIENCES

FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA

(2013) Ye Fu et al.   Nature Communications

Development of Cell-Active N6-Methyladenosine RNA Demethylase FTO Inhibitor

(2012) Baoen Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

(2012) Guanqun Zheng et al.   MOLECULAR CELL

Binding and biomimetic cleavage of the RNA poly(U) by synthetic polyimidazoles

(2012) L. Cheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

N6-methyl-adenosine (m6A) in RNA: An Old Modification with A Novel Epigenetic Function

(2012) Yamei Niu et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO

(2008) Guifang Jia et al.   FEBS LETTERS