NMR analyses on N-hydroxymethylated nucleobases – implications for formaldehyde toxicity and nucleic acid demethylases

5-Formylcytosine Yields DNA–Protein Cross-Links in Nucleosome Core Particles

(2017) Fengchao Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism

(2017) Guillermo Burgos-Barragan et al.   NATURE

The RNA Modification N 6 -methyladenosine and Its Implications in Human Disease

(2017) Pedro J. Batista   GENOMICS PROTEOMICS & BIOINFORMATICS

DNA–Protein Cross-Links: Formation, Structural Identities, and Biological Outcomes

(2015) Natalia Y. Tretyakova et al.   ACCOUNTS OF CHEMICAL RESEARCH

Short-term exposure to formaldehyde promotes oxidative damage and inflammation in the trachea and diaphragm muscle of adult rats

(2015) Luiza Fagundes Lima et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

5-Hydroxymethylcytosine: An epigenetic mark frequently deregulated in cancer

(2015) Leonie I. Kroeze et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Formaldehyde Crosslinking: A Tool for the Study of Chromatin Complexes

(2015) Elizabeth A. Hoffman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen

(2015) Lucas B. Pontel et al.   MOLECULAR CELL

CDA directs metabolism of epigenetic nucleosides revealing a therapeutic window in cancer

(2015) Melania Zauri et al.   NATURE

Organocatalytic removal of formaldehyde adducts from RNA and DNA bases

(2015) Saswata Karmakar et al.   Nature Chemistry

Studies on the Glutathione-Dependent Formaldehyde-Activating Enzyme from Paracoccus denitrificans

(2015) Richard J. Hopkinson et al.   PLoS One

Inosine in DNA and RNA

(2014) Ingrun Alseth et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Isostericity and tautomerism of base pairs in nucleic acids

(2014) Eric Westhof   FEBS LETTERS

Calculations of pKa’s and Redox Potentials of Nucleobases with Explicit Waters and Polarizable Continuum Solvation

(2014) Bishnu Thapa et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells

(2014) Thomas M. Carlile et al.   NATURE

TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor

(2014) Yong Chen et al.   PAIN

Is JmjC Oxygenase Catalysis Limited to Demethylation?

(2013) Richard J. Hopkinson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural insights into how 5-hydroxymethylation influences transcription factor binding

(2013) Lukas Lercher et al.   CHEMICAL COMMUNICATIONS

Structural Basis for Inhibition of the Fat Mass and Obesity Associated Protein (FTO)

(2013) WeiShen Aik et al.   JOURNAL OF MEDICINAL CHEMISTRY

An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers

(2013) Steven A Roberts et al.   NATURE GENETICS

RNA pseudouridylation: new insights into an old modification

(2013) Junhui Ge et al.   TRENDS IN BIOCHEMICAL SCIENCES

FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA

(2013) Ye Fu et al.   Nature Communications

Accumulated hippocampal formaldehyde induces age-dependent memory decline

(2012) Zhiqian Tong et al.   AGE

Mechanisms of human histone and nucleic acid demethylases

(2012) Louise J Walport et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Hydroxylation of methylated CpG dinucleotides reverses stabilisation of DNA duplexes by cytosine 5-methylation

(2011) Armin Thalhammer et al.   CHEMICAL COMMUNICATIONS

Use of LC-MS/MS and Stable Isotopes to Differentiate Hydroxymethyl and Methyl DNA Adducts from Formaldehyde and Nitrosodimethylamine

(2011) Kun Lu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway

(2011) Ivan V Rosado et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Monitoring the Activity of 2-Oxoglutarate Dependent Histone Demethylases by NMR Spectroscopy: Direct Observation of Formaldehyde

(2010) Richard J. Hopkinson et al.   CHEMBIOCHEM

Structural and Mechanistic Studies on γ-Butyrobetaine Hydroxylase

(2010) Ivanhoe K.H. Leung et al.   CHEMISTRY & BIOLOGY

Formaldehyde-releasers in cosmetics: relationship to formaldehyde contact allergy

(2010) Anton de Groot et al.   CONTACT DERMATITIS

Formaldehyde-releasers in cosmetics: relationship to formaldehyde contact allergy

(2010) Anton C. de Groot et al.   CONTACT DERMATITIS

Structural Characterization of Formaldehyde-Induced Cross-Links Between Amino Acids and Deoxynucleosides and Their Oligomers

(2010) Kun Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Studies on the reaction of glutathione and formaldehyde using NMR

(2010) Richard J. Hopkinson et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Clear Differences in Levels of a Formaldehyde-DNA Adduct in Leukocytes of Smokers and Nonsmokers

(2009) M. Wang et al.   CANCER RESEARCH

Formation ofS-[1-(N2-Deoxyguanosinyl)methyl]glutathione between Glutathione and DNA Induced by Formaldehyde

(2009) Kun Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Urine formaldehyde level is inversely correlated to mini mental state examination scores in senile dementia

(2009) Zhiqian Tong et al.   NEUROBIOLOGY OF AGING

Formaldehyde-Induced Histone Modificationsin Vitro

(2008) Kun Lu et al.   CHEMICAL RESEARCH IN TOXICOLOGY