Programmable RNA-based systems for sensing and diagnostic applications

Direct Selection of Fluorescence-Enhancing RNA Aptamers

(2018) Michael Gotrik et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genetically Encoded Catalytic Hairpin Assembly for Sensitive RNA Imaging in Live Cells

(2018) Aruni P. K. K. Karunanayake Mudiyanselage et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Construction of integrated gene logic-chip

(2018) Takeya Masubuchi et al.   Nature Nanotechnology

Designing cell function: assembly of synthetic gene circuits for cell biology applications

(2018) Mingqi Xie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Development of a genetically encodable FRET system using fluorescent RNA aptamers

(2018) Mette D. E. Jepsen et al.   Nature Communications

Fluorogenic RNA Mango aptamers for imaging small non-coding RNAs in mammalian cells

(2018) Alexis Autour et al.   Nature Communications

RNA Structure and Cellular Applications of Fluorogenic Light-Up Aptamers

(2018) Sven Hennig et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers

(2018) Melissa K. Takahashi et al.   Nature Communications

Light-Up RNA Aptamers and Their Cognate Fluorogens: From Their Development to Their Applications

(2017) Farah Bouhedda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Genetically Encoded Fluorescent RNA Sensor for Ratiometric Imaging of MicroRNA in Living Tumor Cells

(2017) Zhan-Ming Ying et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Toward practical application of paper-based microfluidics for medical diagnostics: state-of-the-art and challenges

(2017) Kentaro Yamada et al.   LAB ON A CHIP

RNA imaging: A tale of two G-quadruplexes

(2017) Aaron E Engelhart   Nature Chemical Biology

FASTmiR: an RNA-based sensor for in vitro quantification and live-cell localization of small RNAs

(2017) Kun Huang et al.   NUCLEIC ACIDS RESEARCH

A Fluorescent Split Aptamer for Visualizing RNA–RNA Assembly In Vivo

(2017) Khalid K. Alam et al.   ACS Synthetic Biology

Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components

(2016) Keith Pardee et al.   CELL

Split Spinach Aptamer for Highly Selective Recognition of DNA and RNA at Ambient Temperatures

(2016) Nanami Kikuchi et al.   CHEMBIOCHEM

Opportunities in the design and application of RNA for gene expression control

(2016) Maureen McKeague et al.   NUCLEIC ACIDS RESEARCH

A conformation-induced fluorescence method for microRNA detection

(2016) Sherry S. Aw et al.   NUCLEIC ACIDS RESEARCH

Genetic circuit design automation

(2016) A. A. K. Nielsen et al.   SCIENCE

RNA Fluorescence with Light-Up Aptamers

(2016) Jonathan Ouellet   Frontiers in Chemistry

A renaissance in RNA synthetic biology: new mechanisms, applications and tools for the future

(2015) James Chappell et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Imaging metabolite dynamics in living cells using a Spinach-based riboswitch

(2015) Mingxu You et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic biology devices for in vitro and in vivo diagnostics

(2015) Shimyn Slomovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA Self-Assembly and RNA Nanotechnology

(2014) Wade W. Grabow et al.   ACCOUNTS OF CHEMICAL RESEARCH

RNA Mango Aptamer-Fluorophore: A Bright, High-Affinity Complex for RNA Labeling and Tracking

(2014) Elena V. Dolgosheina et al.   ACS Chemical Biology

Toehold Switches: De-Novo-Designed Regulators of Gene Expression

(2014) Alexander A. Green et al.   CELL

Paper-Based Synthetic Gene Networks

(2014) Keith Pardee et al.   CELL

Broccoli: Rapid Selection of an RNA Mimic of Green Fluorescent Protein by Fluorescence-Based Selection and Directed Evolution

(2014) Grigory S. Filonov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural basis for activity of highly efficient RNA mimics of green fluorescent protein

(2014) Katherine Deigan Warner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Fluorescent Monitoring of RNA Assembly and Processing Using the Split-Spinach Aptamer

(2014) Tucker A. Rogers et al.   ACS Synthetic Biology

Assembling DNA through Affinity Binding to Achieve Ultrasensitive Protein Detection

(2013) Hongquan Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Polyamines and Their Metabolites as Diagnostic Markers of Human Diseases

(2013) Myung Hee Park et al.   Biomolecules & Therapeutics

RAPID-SELEX for RNA Aptamers

(2013) Kylan Szeto et al.   PLoS One

Rational design of modular allosteric aptamer sensor for label-free protein detection

(2012) Gyeong Sook Bang et al.   BIOSENSORS & BIOELECTRONICS

Paper-based nanobiosensors for diagnostics

(2012) Claudio Parolo et al.   CHEMICAL SOCIETY REVIEWS

Automated design of RNA devices

(2012) Farren J Isaacs   Nature Chemical Biology

Rationally designed families of orthogonal RNA regulators of translation

(2012) Vivek K Mutalik et al.   Nature Chemical Biology

An adaptor from translational to transcriptional control enables predictable assembly of complex regulation

(2012) Chang C Liu et al.   NATURE METHODS

Fluorescence Imaging of Cellular Metabolites with RNA

(2012) Jeremy S. Paige et al.   SCIENCE

RNA Mimics of Green Fluorescent Protein

(2011) J. S. Paige et al.   SCIENCE

Grand Challenge Commentary: Informative diagnostics for personalized medicine

(2010) Ryan C Bailey   Nature Chemical Biology

The emerging field of RNA nanotechnology

(2010) Peixuan Guo   Nature Nanotechnology

Genetic control of mammalian T-cell proliferation with synthetic RNA regulatory systems

(2010) Y. Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Label-Free Fluorescent Aptamer Sensor Based on Regulation of Malachite Green Fluorescence

(2009) Weichen Xu et al.   ANALYTICAL CHEMISTRY

miR-21: a small multi-faceted RNA

(2008) Anna M. Krichevsky et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE