Defects in MAP1S-mediated autophagy cause reduction in mouse lifespans especially when fibronectin is overexpressed

Blocking the association of HDAC4 with MAP1S accelerates autophagy clearance of mutant Huntingtin

(2015) Fei Yue et al.   Aging-US

Essential role for autophagy in life span extension

(2015) Frank Madeo et al.   JOURNAL OF CLINICAL INVESTIGATION

Chromosomal mapping of the GFP-LC3 transgene in GFP-LC3 mice

(2014) Akiko Kuma et al.   Autophagy

Elevated levels of mitochondrion-associated autophagy inhibitor LRPPRC are associated with poor prognosis in patients with prostate cancer

(2014) Xianhan Jiang et al.   CANCER

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

Autophagy defects suggested by low levels of autophagy activator MAP1S and high levels of autophagy inhibitor LRPPRC predict poor prognosis of prostate cancer patients

(2014) Xianhan Jiang et al.   MOLECULAR CARCINOGENESIS

Inflammasome: Cancer's friend or foe?

(2014) Michela Terlizzi et al.   PHARMACOLOGY & THERAPEUTICS

Autophagy Inhibitor LRPPRC Suppresses Mitophagy through Interaction with Mitophagy Initiator Parkin

(2014) Jing Zou et al.   PLoS One

Adiponectin Agonist ADP355 Attenuates CCl4-Induced Liver Fibrosis in Mice

(2014) Pradeep Kumar et al.   PLoS One

Inflammasome activation leads to Caspase-1-dependent mitochondrial damage and block of mitophagy

(2014) J. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrion-associated protein LRPPRC suppresses the initiation of basal levels of autophagy via enhancing Bcl-2 stability

(2013) Jing Zou et al.   BIOCHEMICAL JOURNAL

Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors

(2013) A. D. Silk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MAP1S enhances autophagy to suppress tumorigenesis

(2012) Leyuan Liu et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Fibrosis-dependent mechanisms of hepatocarcinogenesis

(2012) David Y. Zhang et al.   HEPATOLOGY

The extracellular matrix: an active or passive player in fibrosis?

(2011) Thomas N. Wight et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Following autophagy step by step

(2011) Tom Hansen et al.   BMC BIOLOGY

Autophagy Enhanced by Microtubule- and Mitochondrion-Associated MAP1S Suppresses Genome Instability and Hepatocarcinogenesis

(2011) R. Xie et al.   CANCER RESEARCH

Microtubule-associated Protein 1S (MAP1S) Bridges Autophagic Components with Microtubules and Mitochondria to Affect Autophagosomal Biogenesis and Degradation

(2011) Rui Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fibronectin: Functional character and role in alcoholic liver disease

(2011) Razia S Aziz-Seible   WORLD JOURNAL OF GASTROENTEROLOGY

Assembly of Fibronectin Extracellular Matrix

(2010) Purva Singh et al.   Annual Review of Cell and Developmental Biology

Acetylated microtubules are required for fusion of autophagosomes with lysosomes

(2010) Rui Xie et al.   BMC CELL BIOLOGY

Ubiquitination of α5β1 Integrin Controls Fibroblast Migration through Lysosomal Degradation of Fibronectin-Integrin Complexes

(2010) Viola Hélène Lobert et al.   DEVELOPMENTAL CELL

Targeting the p27 E3 ligase SCFSkp2 results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy

(2008) Q. Chen et al.   BLOOD

Integrins and the activation of latent transforming growth factor β1 – An intimate relationship

(2008) P WIPFF et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Hepatocellular adenomas: Magnetic resonance imaging features as a function of molecular pathological classification

(2008) Hervé Laumonier et al.   HEPATOLOGY

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE