Autophagy defects suggested by low levels of autophagy activator MAP1S and high levels of autophagy inhibitor LRPPRC predict poor prognosis of prostate cancer patients

Elevated levels of mitochondrion-associated autophagy inhibitor LRPPRC are associated with poor prognosis in patients with prostate cancer

(2014) Xianhan Jiang et al.   CANCER

Autophagy Inhibitor LRPPRC Suppresses Mitophagy through Interaction with Mitophagy Initiator Parkin

(2014) Jing Zou et al.   PLoS One

Mitochondrion-associated protein LRPPRC suppresses the initiation of basal levels of autophagy via enhancing Bcl-2 stability

(2013) Jing Zou et al.   BIOCHEMICAL JOURNAL

MAP1S enhances autophagy to suppress tumorigenesis

(2012) Leyuan Liu et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Autophagy Enhanced by Microtubule- and Mitochondrion-Associated MAP1S Suppresses Genome Instability and Hepatocarcinogenesis

(2011) R. Xie et al.   CANCER RESEARCH

Microtubule-associated Protein 1S (MAP1S) Bridges Autophagic Components with Microtubules and Mitochondria to Affect Autophagosomal Biogenesis and Degradation

(2011) Rui Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

(2010) M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial oxidative stress elicits chromosomal instability after exposure to isocyanates in human kidney epithelial cells

(2009) Pradyumna K. Mishra et al.   FREE RADICAL RESEARCH

Overexpression of Tiam1 in hepatocellular carcinomas predicts poor prognosis of HCC patients

(2008) Yi Ding et al.   INTERNATIONAL JOURNAL OF CANCER

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE