Mechanistic Studies on the Palladium-Catalyzed Direct C-5 Arylation of Imidazoles: The Fundamental Role of the Azole as a Ligand for Palladium

Imidazole analogues of resveratrol: synthesis and cancer cell growth evaluation

(2015) Fabio Bellina et al.   TETRAHEDRON

Cross-Coupling of Heteroarenes by CH Functionalization: Recent Progress towards Direct Arylation and Heteroarylation Reactions Involving Heteroarenes Containing One Heteroatom

(2014) Renzo Rossi et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of Biaryls through Aromatic CH Bond Activation: A Review of Recent Developments

(2014) Ibrar Hussain et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of (Poly)fluorobiphenyls through Metal-catalyzed CH Bond Activation/Arylation of (Poly)fluorobenzene Derivatives

(2014) Mian He et al.   ChemCatChem

Room-temperature palladium-catalyzed direct 2-arylation of benzoxazoles with aryl and heteroaryl bromides

(2014) Feng Gao et al.   CHEMICAL COMMUNICATIONS

Effects of PAr3 Ligands on Direct Arylation of Heteroarenes with Isolated [Pd(2,6-Me2C6H3)(μ-O2CMe)(PAr3)]4 Complexes

(2014) Masayuki Wakioka et al.   ORGANOMETALLICS

Synthesis of Multiply Arylated Heteroarenes, Including Bioactive Derivatives, via Palladium-Catalyzed Direct C–H Arylation of Heteroarenes with (Pseudo)Aryl Halides or Aryliodonium Salts

(2014) Renzo Rossi et al.   SYNTHESIS-STUTTGART

Synthesis and Optical Properties of Imidazole-Based Fluorophores having High Quantum Yields

(2014) Marco Lessi et al.   ChemPlusChem

Autocatalytic Intermolecular versus Intramolecular Deprotonation in CH Bond Activation of Functionalized Arenes by Ruthenium(II) or Palladium(II) Complexes

(2013) Indira Fabre et al.   CHEMISTRY-A EUROPEAN JOURNAL

“On Water”, Phosphine-Free Palladium-Catalyzed Room Temperature CH Arylation of Indoles

(2013) Saidul Islam et al.   CHEMISTRY-A EUROPEAN JOURNAL

Pyrazole containing natural products: Synthetic preview and biological significance

(2013) Vinod Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Mild Palladium-Catalyzed Regioselective Direct Arylation of Azoles Promoted by Tetrabutylammonium Acetate

(2013) Fabio Bellina et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

C–H bond activation enables the rapid construction and late-stage diversification of functional molecules

(2013) Joanna Wencel-Delord et al.   Nature Chemistry

Factors Controlling the Reactivity of Heteroarenes in Direct Arylation with Arylpalladium Acetate Complexes

(2013) Masayuki Wakioka et al.   ORGANOMETALLICS

Ligand controlled orthogonal base-assisted direct C–H bond arylation in oxa(thia)zole-4-carboxylate series. New insights in nCMD mechanism

(2013) Laure Théveau et al.   TETRAHEDRON

On the Interpretation of Deuterium Kinetic Isotope Effects in CH Bond Functionalizations by Transition-Metal Complexes

(2012) Eric M. Simmons et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Imidazole as a parent π-conjugated backbone in charge-transfer chromophores

(2012) Jiří Kulhánek et al.   Beilstein Journal of Organic Chemistry

Recent advances in organic mechanofluorochromic materials

(2012) Zhenguo Chi et al.   CHEMICAL SOCIETY REVIEWS

Origins of regioselectivity of the palladium-catalyzed (aromatic)CH bond metalation–deprotonation

(2012) Serge I. Gorelsky   COORDINATION CHEMISTRY REVIEWS

A Frozen Analogue Approach to Aminopyridinylimidazoles Leading to Novel and Promising p38 MAP Kinase Inhibitors

(2012) Roland Selig et al.   JOURNAL OF MEDICINAL CHEMISTRY

Trisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase Inhibitors

(2012) Johan Gising et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mechanistic Studies on Direct Arylation of Pyridine N-Oxide: Evidence for Cooperative Catalysis between Two Distinct Palladium Centers

(2012) Yichen Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent Progress Towards Transition-Metal-Catalyzed Direct Arylation of Heteroarenes

(2012) Ye-Xiang Su et al.   MINI-REVIEWS IN ORGANIC CHEMISTRY

Direct Arylation of 2-Methylthiophene with Isolated [PdAr(μ-O2CR)(PPh3)]n Complexes: Kinetics and Mechanism

(2012) Masayuki Wakioka et al.   ORGANOMETALLICS

Recent advances in direct C–H arylation: Methodology, selectivity and mechanism in oxazole series

(2011) Cécile Verrier et al.   Beilstein Journal of Organic Chemistry

Kinetic Isotope Effects in the Study of Organometallic Reaction Mechanisms

(2011) Mar Gómez-Gallego et al.   CHEMICAL REVIEWS

Semiconducting π-Conjugated Systems in Field-Effect Transistors: A Material Odyssey of Organic Electronics

(2011) Chengliang Wang et al.   CHEMICAL REVIEWS

Mechanism Selection for Regiocontrol in Base-Assisted, Palladium-Catalysed Direct CH Coupling with Halides: First Approach for Oxazole- and Thiazole-4-Carboxylates

(2011) Laure Théveau et al.   CHEMISTRY-A EUROPEAN JOURNAL

Mechanistic Origin of Ligand-Controlled Regioselectivity in Pd-Catalyzed CH Activation/Arylation of Thiophenes

(2011) Shi-Ya Tang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Benzobisoxazole Cruciforms: Heterocyclic Fluorophores with Spatially Separated Frontier Molecular Orbitals

(2011) Jaebum Lim et al.   JOURNAL OF ORGANIC CHEMISTRY

Direct Arylation of Simple Azoles Catalyzed by 1,10-Phenanthroline Containing Palladium Complexes: An Investigation of C4 Arylation of Azoles and the Synthesis of Triarylated Azoles by Sequential Arylation

(2011) Fumitoshi Shibahara et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Direct Arylation of Heteroaromatic Compounds: Improved Conditions Utilizing Controlled Microwave Heating

(2011) Mostafa Baghbanzadeh et al.   JOURNAL OF ORGANIC CHEMISTRY

Analysis of the Palladium-Catalyzed (Aromatic)C–H Bond Metalation–Deprotonation Mechanism Spanning the Entire Spectrum of Arenes

(2011) Serge I. Gorelsky et al.   JOURNAL OF ORGANIC CHEMISTRY

Assessment of the Intermediacy of Arylpalladium Carboxylate Complexes in the Direct Arylation of Benzene: Evidence for C−H Bond Cleavage by “Ligandless” Species

(2011) Yichen Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Autocatalysis for C–H Bond Activation by Ruthenium(II) Complexes in Catalytic Arylation of Functional Arenes

(2011) Emmanuel Ferrer Flegeau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct C5-Arylation Reaction between Imidazoles and Aryl Chlorides Catalyzed by Palladium Complexes with Phosphines and N-Heterocyclic Carbenes

(2011) P. Vijaya Kumar et al.   ORGANOMETALLICS

Regioselective Functionalization of the Imidazole Ring via Transition Metal-Catalyzed CN and CC Bond Forming Reactions

(2010) Fabio Bellina et al.   ADVANCED SYNTHESIS & CATALYSIS

A General Catalyst for the β-Selective C-H Bond Arylation of Thiophenes with Iodoarenes

(2010) Kirika Ueda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct multiple C–H bond arylation reaction of heteroarenes catalyzed by cationic palladium complex bearing 1,10-phenanthroline

(2010) Fumitoshi Shibahara et al.   CHEMICAL COMMUNICATIONS

Overview of the Mechanistic Work on the Concerted Metallation–Deprotonation Pathway

(2010) David Lapointe et al.   CHEMISTRY LETTERS

Palladium-Catalyzed Arylation Reactions: A Mechanistic Perspective

(2010) Madeleine Livendahl et al.   ISRAEL JOURNAL OF CHEMISTRY

Amaranzoles B−F, Imidazole-2-carboxy Steroids from the Marine SpongePhorbas amaranthus. C24-N- and C24-O-Analogues from a Divergent Oxidative Biosynthesis

(2010) Brandon I. Morinaka et al.   JOURNAL OF ORGANIC CHEMISTRY

Mechanistic Analysis of AzineN-Oxide Direct Arylation: Evidence for a Critical Role of Acetate in the Pd(OAc)2Precatalyst

(2010) Ho-Yan Sun et al.   JOURNAL OF ORGANIC CHEMISTRY

C−H Bonds as Ubiquitous Functionality: A General Approach to Complex Arylated Imidazoles via Regioselective Sequential Arylation of All Three C−H Bonds and RegioselectiveN-Alkylation Enabled by SEM-Group Transposition

(2010) Jung Min Joo et al.   JOURNAL OF ORGANIC CHEMISTRY

Room-Temperature Direct Arylation of Polyfluorinated Arenes under Biphasic Conditions

(2010) Olivier René et al.   ORGANIC LETTERS

Transition-Metal-Catalyzed Direct Arylation of (Hetero)Arenes by CH Bond Cleavage

(2009) Lutz Ackermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic C–C coupling through C–H arylation of arenes or heteroarenes

(2009) Gian Paolo Chiusoli et al.   COORDINATION CHEMISTRY REVIEWS

Establishment of Broadly Applicable Reaction Conditions for the Palladium-Catalyzed Direct Arylation of Heteroatom-Containing Aromatic Compounds

(2009) Benoît Liégault et al.   JOURNAL OF ORGANIC CHEMISTRY

Phosphine-free palladium-catalysed direct 5-arylation of imidazole derivatives at low catalyst loading

(2009) Julien Roger et al.   TETRAHEDRON

Recent advances in the synthesis of (hetero)aryl-substituted heteroarenes via transition metal-catalysed direct (hetero)arylation of heteroarene C–H bonds with aryl halides or pseudohalides, diaryliodonium salts, and potassium aryltrifluoroborates

(2009) Fabio Bellina et al.   TETRAHEDRON

Direct arylations on water: synthesis of 2,5-disubstituted oxazoles balsoxin and texaline

(2008) Stephan A. Ohnmacht et al.   CHEMICAL COMMUNICATIONS

Regioselective Synthesis of 4,5-Diaryl-1-methyl-1H-imidazoles Including Highly Cytotoxic Derivatives by Pd-Catalyzed Direct C-5 Arylation of 1-Methyl-1H-imidazole with Aryl Bromides

(2008) Fabio Bellina et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Direct (Hetero)arylation of Ethyl Oxazole-4-carboxylate: An Efficient Access to (Hetero)aryloxazoles

(2008) Cécile Verrier et al.   JOURNAL OF ORGANIC CHEMISTRY

C2, C5, and C4 AzoleN-Oxide Direct Arylation Including Room-Temperature Reactions

(2008) Louis-Charles Campeau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Analysis of the Concerted Metalation-Deprotonation Mechanism in Palladium-Catalyzed Direct Arylation Across a Broad Range of Aromatic Substrates

(2008) Serge I. Gorelsky et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct C-2 Arylation of Alkyl 4-Thiazolecarboxylates: New Insights in Synthesis of Heterocyclic Core of Thiopeptide Antibiotics

(2008) Thibaut Martin et al.   ORGANIC LETTERS

Palladium-Catalyzed Direct Heck Arylation of Dual π-Deficient/π-Excessive Heteroaromatics. Synthesis of C-5 Arylated Imidazo[1,5-a]pyrazines

(2008) Jian-Xin Wang et al.   ORGANIC LETTERS

An azole, an amide and a limonoid from Vepris uguenensis (Rutaceae)

(2008) Peter K. Cheplogoi et al.   PHYTOCHEMISTRY

Highly selective synthesis of 4(5)-aryl-, 2,4(5)-diaryl-, and 4,5-diaryl-1H-imidazoles via Pd-catalyzed direct C-5 arylation of 1-benzyl-1H-imidazole

(2008) Fabio Bellina et al.   TETRAHEDRON

Bidentate phosphines as ligands in the palladium-catalyzed intramolecular arylation: the intermolecular base-assisted proton abstraction mechanism

(2008) Sergio Pascual et al.   TETRAHEDRON