Acetic Acid Accelerated Visible-Light Photoredox CatalyzedN-Demethylation ofN,N-Dimethylaminophenyl Derivatives

Halogenase-Inspired Oxidative Chlorination Using Flavin Photocatalysis

(2016) Thea Hering et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Improving Drug Design: An Update on Recent Applications of Efficiency Metrics, Strategies for Replacing Problematic Elements, and Compounds in Nontraditional Drug Space

(2016) Nicholas A. Meanwell   CHEMICAL RESEARCH IN TOXICOLOGY

Scaffold Repurposing of Old Drugs Towards New Cancer Drug Discovery

(2016) Haijun Chen et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Big Data from Pharmaceutical Patents: A Computational Analysis of Medicinal Chemists’ Bread and Butter

(2016) Nadine Schneider et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of metapristone through an efficient N-demethylation of mifepristone

(2016) Jianlei Wu et al.   RSC Advances

Amine Functionalization via Oxidative Photoredox Catalysis: Methodology Development and Complex Molecule Synthesis

(2015) Joel W. Beatty et al.   ACCOUNTS OF CHEMICAL RESEARCH

Visible-Light-Induced Decarboxylative Functionalization of Carboxylic Acids and Their Derivatives

(2015) Jun Xuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemistry and Biology of Resveratrol-Derived Natural Products

(2015) Mitchell H. Keylor et al.   CHEMICAL REVIEWS

Evolutions in fragment-based drug design: the deconstruction–reconstruction approach

(2015) Haijun Chen et al.   DRUG DISCOVERY TODAY

Designing novel building blocks is an overlooked strategy to improve compound quality

(2015) Frederick W. Goldberg et al.   DRUG DISCOVERY TODAY

Antioxidant Activity of Magnolol and Honokiol: Kinetic and Mechanistic Investigations of Their Reaction with Peroxyl Radicals

(2015) Riccardo Amorati et al.   JOURNAL OF ORGANIC CHEMISTRY

Ion channels enable electrical communication in bacterial communities

(2015) Arthur Prindle et al.   NATURE

Long-Lived Charge Separation and Applications in Artificial Photosynthesis

(2014) Shunichi Fukuzumi et al.   ACCOUNTS OF CHEMICAL RESEARCH

Advances in Radical-Trapping Antioxidant Chemistry in the 21st Century: A Kinetics and Mechanisms Perspective

(2014) Keith U. Ingold et al.   CHEMICAL REVIEWS

Biotransformation and bioactivation reactions of alicyclic amines in drug molecules

(2014) Jayaprakasam Bolleddula et al.   DRUG METABOLISM REVIEWS

The Unique Pharmacological Characteristics of Mifepristone (RU486): From Terminating Pregnancy to Preventing Cancer Metastasis

(2014) Jianzhong Chen et al.   MEDICINAL RESEARCH REVIEWS

Acetic Acid Promoted Metal-Free Aerobic Carbon–Carbon Bond Forming Reactions at α-Position of Tertiary Amines

(2014) Hirofumi Ueda et al.   ORGANIC LETTERS

Solar Synthesis: Prospects in Visible Light Photocatalysis

(2014) D. M. Schultz et al.   SCIENCE

Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis

(2013) Christopher K. Prier et al.   CHEMICAL REVIEWS

Generation, Validation, and Application of a P450 Homology Model

(2013) Benjamin Lewis et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Mechanistic Insights and Kinetic Analysis for the Oxidative Hydroxylation of Arylboronic Acids by Visible Light Photoredox Catalysis: A Metal-Free Alternative

(2013) Spencer P. Pitre et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanistic Investigation of Oxidative Mannich Reaction with tert-Butyl Hydroperoxide. The Role of Transition Metal Salt

(2013) Maxim O. Ratnikov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mitigating Heterocycle Metabolism in Drug Discovery

(2012) David J. St. Jean et al.   JOURNAL OF MEDICINAL CHEMISTRY

Photoredox Catalysis as an Efficient Tool for the Aerobic Oxidation of Amines and Alcohols: Bioinspired Demethylations and Condensations

(2012) Magnus Rueping et al.   ACS Catalysis

Highly Efficient Aerobic Oxidative Hydroxylation of Arylboronic Acids: Photoredox Catalysis Using Visible Light

(2011) You-Quan Zou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-free oxygenation of cyclohexane with oxygen catalyzed by 9-mesityl-10-methylacridinium and hydrogen chloride under visible light irradiation

(2011) Kei Ohkubo et al.   CHEMICAL COMMUNICATIONS

Role of Cyclic Tertiary Amine Bioactivation to Reactive Iminium Species: Structure Toxicity Relationship

(2011) Lucija Peterlin Masic   CURRENT DRUG METABOLISM

Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan

(2011) Silvestre Alavez et al.   NATURE

Understanding Hydrogen Atom Transfer: From Bond Strengths to Marcus Theory

(2010) James M. Mayer   ACCOUNTS OF CHEMICAL RESEARCH

Visible light photocatalysis as a greener approach to photochemical synthesis

(2010) Tehshik P. Yoon et al.   Nature Chemistry

Unexpected Acid Catalysis in Reactions of Peroxyl Radicals with Phenols

(2009) Luca Valgimigli et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Simultaneous production of p-tolualdehyde and hydrogen peroxide in photocatalytic oxygenation of p-xylene and reduction of oxygen with 9-mesityl-10-methylacridinium ion derivatives

(2009) Kei Ohkubo et al.   CHEMICAL COMMUNICATIONS