A New Model of Sensorial Neuron-Like Cells for HTS of Novel Analgesics for Neuropathic Pain

Next-generation phenotypic screening

(2016) Scott J Warchal et al.   Future Medicinal Chemistry

Targeting the Nerve Growth Factor (NGF) Pathway in Drug Discovery. Potential Applications to New Therapies for Chronic Pain

(2016) Bryan H. Norman et al.   JOURNAL OF MEDICINAL CHEMISTRY

Neuronal cell lines as model dorsal root ganglion neurons

(2016) Kathleen Yin et al.   Molecular Pain

Molecular structure and function of P2X receptors

(2016) Chloé Habermacher et al.   NEUROPHARMACOLOGY

High throughput screening technologies for ion channels

(2015) Hai-bo Yu et al.   ACTA PHARMACOLOGICA SINICA

Seven novel modulators of the analgesic target NaV1.7 uncovered using a high-throughput venom-based discovery approach

(2015) Julie K Klint et al.   BRITISH JOURNAL OF PHARMACOLOGY

Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis

(2015) Nanna B Finnerup et al.   LANCET NEUROLOGY

Lighting up G protein-coupled purinergic receptors with engineered fluorescent ligands

(2015) Francisco Ciruela et al.   NEUROPHARMACOLOGY

Differential expression of ATP-gated P2X receptors in DRG between chronic neuropathic pain and visceralgia rat models

(2015) Lin Chen et al.   Purinergic Signalling

Mouse DRG Cell Line with Properties of Nociceptors

(2015) Ciara Doran et al.   PLoS One

Chemical Library Screening and Structure-Function Relationship Studies Identify Bisacodyl as a Potent and Selective Cytotoxic Agent Towards Quiescent Human Glioblastoma Tumor Stem-Like Cells

(2015) Maria Zeniou et al.   PLoS One

A peripherally acting, selective T-type calcium channel blocker, ABT-639, effectively reduces nociceptive and neuropathic pain in rats

(2014) Michael F. Jarvis et al.   BIOCHEMICAL PHARMACOLOGY

HTS assays for developing the molecular pharmacology of ion channels

(2014) Owen B McManus   CURRENT OPINION IN PHARMACOLOGY

Allodynia and hyperalgesia in neuropathic pain: clinical manifestations and mechanisms

(2014) Troels S Jensen et al.   LANCET NEUROLOGY

Label-free drug discovery

(2014) Ye Fang   Frontiers in Pharmacology

Activation and desensitization of TRPV1 channels in sensory neurons by the PPARα agonist palmitoylethanolamide

(2012) Paolo Ambrosino et al.   BRITISH JOURNAL OF PHARMACOLOGY

Calcium channel functions in pain processing

(2010) John Park et al.   Channels

Deconvolution of complex G protein–coupled receptor signaling in live cells using dynamic mass redistribution measurements

(2010) Ralf Schröder et al.   NATURE BIOTECHNOLOGY

Characterization of endogenous calcium responses in neuronal cell lines

(2009) Irina Vetter et al.   BIOCHEMICAL PHARMACOLOGY

Modulation of sensory neuron potassium conductances by anandamide indicates roles for metabolites

(2008) R M Evans et al.   BRITISH JOURNAL OF PHARMACOLOGY