ANRIL: Molecular Mechanisms and Implications in Human Health

Quantitative assessment of higher-order chromatin structure of the INK4/ARF locus in human senescent cells

(2012) Akiyuki Hirosue et al.   AGING CELL

CVD-associated non-coding RNA, ANRIL, modulates expression of atherogenic pathways in VSMC

(2012) Ada Congrains et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genome-wide association study of glioma and meta-analysis

(2012) Preetha Rajaraman et al.   HUMAN GENETICS

Intronic RNAs mediate EZH2 regulation of epigenetic targets

(2012) Sònia Guil et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cis-acting noncoding RNAs: friends and foes

(2012) Sònia Guil et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Renal, cardiovascular and metabolic effects of fetal programming

(2012) N. Koleganova et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Computational Prediction of Polycomb-Associated Long Non-Coding RNAs

(2012) Galina V. Glazko et al.   PLoS One

Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B

(2011) Ada Congrains et al.   ATHEROSCLEROSIS

Long Noncoding RNA, Polycomb, and the Ghosts Haunting INK4b-ARF-INK4a Expression

(2011) F. Aguilo et al.   CANCER RESEARCH

miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA

(2011) Thomas B Hansen et al.   EMBO JOURNAL

Common genetic variants associated with open-angle glaucoma

(2011) Wishal D. Ramdas et al.   HUMAN MOLECULAR GENETICS

Role of Noncoding RNA ANRIL in Genesis of Plexiform Neurofibromas in Neurofibromatosis Type 1

(2011) Eric Pasmant et al.   JNCI-Journal of the National Cancer Institute

9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

(2011) Olivier Harismendy et al.   NATURE

Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1

(2011) Kathryn P Burdon et al.   NATURE GENETICS

Type 2 diabetes and polymorphisms on chromosome 9p21: A meta-analysis

(2011) D. Cugino et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

T-cell factor 3 (Tcf3) deletion increases somatic cell reprogramming by inducing epigenome modifications

(2011) F. Lluis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of histone methylation and demethylation in adipogenesis and obesity

(2011) Masashi Okamura et al.   Organogenesis

ANRIL Expression Is Associated With Atherosclerosis Risk at Chromosome 9p21

(2010) Lesca M. Holdt et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Epigenetic regulation of theINK4b-ARF-INK4alocus

(2010) Nikolay Popov et al.   Epigenetics

ANRIL, a long, noncoding RNA, is an unexpected major hotspot in GWAS

(2010) Eric Pasmant et al.   FASEB JOURNAL

Short RNAs Are Transcribed from Repressed Polycomb Target Genes and Interact with Polycomb Repressive Complex-2

(2010) Aditi Kanhere et al.   MOLECULAR CELL

Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a

(2010) Kyoko L. Yap et al.   MOLECULAR CELL

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice

(2010) Axel Visel et al.   NATURE

A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese

(2010) Satoko Uno et al.   NATURE GENETICS

Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk

(2010) Amy L Sherborne et al.   NATURE GENETICS

Genome-wide association study identifies five new breast cancer susceptibility loci

(2010) Clare Turnbull et al.   NATURE GENETICS

Epigenetics and cardiovascular disease

(2010) José M. Ordovás et al.   Nature Reviews Cardiology

Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15 INK4B tumor suppressor gene

(2010) Y Kotake et al.   ONCOGENE

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression

(2010) Michael S. Cunnington et al.   PLoS Genetics

Expression of Linear and Novel Circular Forms of an INK4/ARF-Associated Non-Coding RNA Correlates with Atherosclerosis Risk

(2010) Christin E. Burd et al.   PLoS Genetics

Anti-aging activity of theInk4/Arflocus

(2009) Ander Matheu et al.   AGING CELL

Sequence variants on chromosome 9p21.3 confer risk for atherosclerotic stroke

(2009) Andreas Gschwendtner et al.   ANNALS OF NEUROLOGY

Polycomb CBX7 Promotes Initiation of Heritable Repression of Genes Frequently Silenced with Cancer-Specific DNA Hypermethylation

(2009) H. P. Mohammad et al.   CANCER RESEARCH

Histone modifications at human enhancers reflect global cell-type-specific gene expression

(2009) Nathaniel D. Heintzman et al.   NATURE

The Ink4/Arf locus is a barrier for iPS cell reprogramming

(2009) Han Li et al.   NATURE

New common variants affecting susceptibility to basal cell carcinoma

(2009) Simon N Stacey et al.   NATURE GENETICS

Chromosome 9p21.3 genotype is associated with vascular dementia and Alzheimer's disease

(2009) Enzo Emanuele et al.   NEUROBIOLOGY OF AGING

Genome-wide associations studies for melanoma and nevi

(2009) Iwei Yeh et al.   Pigment Cell & Melanoma Research

Relationship between CAD Risk Genotype in the Chromosome 9p21 Locus and Gene Expression. Identification of Eight New ANRIL Splice Variants

(2009) Lasse Folkersen et al.   PLoS One

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

(2009) Ahmad M. Khalil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a Shared Genetic Susceptibility Locus for Coronary Heart Disease and Periodontitis

(2009) Arne S. Schaefer et al.   PLoS Genetics

Kcnq1ot1 Antisense Noncoding RNA Mediates Lineage-Specific Transcriptional Silencing through Chromatin-Level Regulation

(2008) Radha Raman Pandey et al.   MOLECULAR CELL

Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

(2008) Wenqiang Yu et al.   NATURE

A NMR strategy to unambiguously distinguish nucleic acid hairpin and duplex conformations applied to a Xist RNA A-repeat

(2008) Malgorzata M. Duszczyk et al.   NUCLEIC ACIDS RESEARCH

Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences

(2008) C. Vincenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome

(2008) J. Zhao et al.   SCIENCE

Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains

(2008) Manching Ku et al.   PLoS Genetics