p53-Sensitive Epileptic Behavior and Inflammation in Ft1 Hypomorphic Mice

Mice with reduced expression of the telomere-associated protein Ft1 develop p53-sensitive progeroid traits

(2018) Mattia La Torre et al.   AGING CELL

Respiratory dysfunction progresses with age in Kcna1 -null mice, a model of sudden unexpected death in epilepsy

(2018) Kristina A. Simeone et al.   EPILEPSIA

Genomic instability and DNA replication defects in progeroid syndromes

(2018) Romina Burla et al.   Nucleus

Genomic instability and DNA replication defects in progeroid syndromes

(2018) Romina Burla et al.   Nucleus

Immunosenescence and Inflamm-Aging As Two Sides of the Same Coin: Friends or Foes?

(2018) Tamas Fulop et al.   Frontiers in Immunology

Age- and Tissue-Specific Expression of Senescence Biomarkers in Mice

(2018) Adam D. Hudgins et al.   Frontiers in Genetics

Machine vision methods for analyzing social interactions

(2017) Alice A. Robie et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Citron Kinase Deficiency Leads to Chromosomal Instability and TP53-Sensitive Microcephaly

(2017) Federico Tommaso Bianchi et al.   Cell Reports

The Ageing Brain: Effects on DNA Repair and DNA Methylation in Mice

(2017) Sabine Langie et al.   Genes

Metabolic Control of Longevity

(2016) Carlos López-Otín et al.   CELL

The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence

(2016) Romina Burla et al.   Open Biology

Mammalian telomeres and their partnership with lamins

(2016) Romina Burla et al.   Nucleus

Alzheimer's disease: An acquired neurodegenerative laminopathy

(2016) Bess Frost   Nucleus

Mammalian telomeres and their partnership with lamins

(2016) Romina Burla et al.   Nucleus

Alzheimer's disease: An acquired neurodegenerative laminopathy

(2016) Bess Frost   Nucleus

Osteoblast-Specific Expression of the Fibrous Dysplasia (FD)-Causing MutationGsαR201CProduces a High Bone Mass Phenotype but Does Not Reproduce FD in the Mouse

(2015) Cristina Remoli et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Transcriptional Response of Human Neurospheres to Helper-Dependent CAV-2 Vectors Involves the Modulation of DNA Damage Response, Microtubule and Centromere Gene Groups

(2015) Stefania Piersanti et al.   PLoS One

Modeling Human Neural FunctionalityIn Vitro: Three-Dimensional Culture for Dopaminergic Differentiation

(2015) Daniel Simão et al.   TISSUE ENGINEERING PART A

Seizures and Epilepsy: An Overview for Neuroscientists

(2015) C. E. Stafstrom et al.   Cold Spring Harbor Perspectives in Medicine

AKTIP/Ft1, a New Shelterin-Interacting Factor Required for Telomere Maintenance

(2015) Romina Burla et al.   PLoS Genetics

ILAE Official Report: A practical clinical definition of epilepsy

(2014) Robert S. Fisher et al.   EPILEPSIA

Constitutive Expression of GsαR201Cin Mice Produces a Heritable, Direct Replica of Human Fibrous Dysplasia Bone Pathology and Demonstrates Its Natural History

(2014) Isabella Saggio et al.   JOURNAL OF BONE AND MINERAL RESEARCH

DNA Damage and Its Links to Neurodegeneration

(2014) Ram Madabhushi et al.   NEURON

Genetic Epilepsy Syndromes Without Structural Brain Abnormalities: Clinical Features and Experimental Models

(2014) Renzo Guerrini et al.   Neurotherapeutics

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Maintaining genome stability in the nervous system

(2013) Peter J McKinnon   NATURE NEUROSCIENCE

Aging, Cellular Senescence, and Cancer

(2012) Judith Campisi   Annual Review of Physiology

Neuronal circuits in epilepsy: Do they matter?

(2012) Edward H. Bertram   EXPERIMENTAL NEUROLOGY

Transcompartmental reversal of single fibre hyperexcitability in juxtaparanodal Kv1.1-deficient vagus nerve axons by activation of nodal KCNQ channels

(2012) Edward Glasscock et al.   JOURNAL OF PHYSIOLOGY-LONDON

Spontaneous epileptiform discharges in a mouse model of Alzheimer's disease are suppressed by antiepileptic drugs that block sodium channels

(2011) Sofya Ziyatdinova et al.   EPILEPSY RESEARCH

Critical review of current animal models of seizures and epilepsy used in the discovery and development of new antiepileptic drugs

(2011) Wolfgang Löscher   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

The lamin protein family

(2011) Travis A Dittmer et al.   GENOME BIOLOGY

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

Electroclinical characterization of epileptic seizures in leucine-rich, glioma-inactivated 1-deficient mice

(2010) Elodie Chabrol et al.   BRAIN

Mutations in PNKP cause microcephaly, seizures and defects in DNA repair

(2010) Jun Shen et al.   NATURE GENETICS

Epilepsy in the elderly

(2009) Ilo E. Leppik et al.   Annals of the New York Academy of Sciences

Anti-inflammatory and pro-inflammatory roles of TGF-β, IL-10, and IL-22 in immunity and autoimmunity

(2009) Shomyseh Sanjabi et al.   CURRENT OPINION IN PHARMACOLOGY

Amyloid  -Induced Neuronal Hyperexcitability Triggers Progressive Epilepsy

(2009) R. Minkeviciene et al.   JOURNAL OF NEUROSCIENCE

The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1

(2009) Youngsoo Lee et al.   NATURE NEUROSCIENCE

Abnormal neuronal networks and seizure susceptibility in mice overexpressing the APP intracellular domain

(2009) D.L. Vogt et al.   NEUROBIOLOGY OF AGING