Alzheimer's disease: An acquired neurodegenerative laminopathy

Lamin Dysfunction Mediates Neurodegeneration in Tauopathies

(2016) Bess Frost et al.   CURRENT BIOLOGY

PML isoform II plays a critical role in nuclear lipid droplet formation

(2016) Yuki Ohsaki et al.   JOURNAL OF CELL BIOLOGY

Mutation of the nuclear lamin geneLMNB2in progressive myoclonus epilepsy with early ataxia

(2015) John A. Damiano et al.   HUMAN MOLECULAR GENETICS

Connecting the dots between tau dysfunction and neurodegeneration

(2015) Bess Frost et al.   TRENDS IN CELL BIOLOGY

Age-Associated Loss of Lamin-B Leads to Systemic Inflammation and Gut Hyperplasia

(2014) Haiyang Chen et al.   CELL

Loss of lamin B1 results in prolongation of S phase and decondensation of chromosome territories

(2014) Jordi Camps et al.   FASEB JOURNAL

Expression of progerin in aging mouse brains reveals structural nuclear abnormalities without detectible significant alterations in gene expression, hippocampal stem cells or behavior

(2014) Jean-Ha Baek et al.   HUMAN MOLECULAR GENETICS

Tau promotes neurodegeneration through global chromatin relaxation

(2014) Bess Frost et al.   NATURE NEUROSCIENCE

Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape

(2013) P. P. Shah et al.   GENES & DEVELOPMENT

Lamin B1 fluctuations have differential effects on cellular proliferation and senescence

(2013) Oliver Dreesen et al.   JOURNAL OF CELL BIOLOGY

Nuclear calcium signalling in the regulation of brain function

(2013) Hilmar Bading   NATURE REVIEWS NEUROSCIENCE

Lamin B1 loss is a senescence-associated biomarker

(2012) Adam Freund et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA

(2012) H.-J. Jung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unique Preservation of Neural Cells in Hutchinson- Gilford Progeria Syndrome Is Due to the Expression of the Neural-Specific miR-9 MicroRNA

(2012) Xavier Nissan et al.   Cell Reports

The role of nuclear lamin B1 in cell proliferation and senescence

(2011) T. Shimi et al.   GENES & DEVELOPMENT

Nuclear lamins and laminopathies

(2011) Howard J. Worman   JOURNAL OF PATHOLOGY

Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons

(2011) Catherine Coffinier et al.   MOLECULAR BIOLOGY OF THE CELL

Mouse B-Type Lamins Are Required for Proper Organogenesis But Not by Embryonic Stem Cells

(2011) Y. Kim et al.   SCIENCE

The nucleoplasmic reticulum: form and function

(2011) Ashraf Malhas et al.   TRENDS IN CELL BIOLOGY

Not Just Fat: The Structure and Function of the Lipid Droplet

(2011) T. Fujimoto et al.   Cold Spring Harbor Perspectives in Biology

Loss of a DNA binding site within the tail of prelamin A contributes to altered heterochromatin anchorage by progerin

(2010) Francine Bruston et al.   FEBS LETTERS

Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency

(2010) C. Coffinier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ABC50 Promotes Translation Initiation in Mammalian Cells

(2009) Sonia Paytubi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lamin B1 controls oxidative stress responses via Oct-1

(2009) Ashraf N. Malhas et al.   JOURNAL OF CELL BIOLOGY

Lamin B1 maintains the functional plasticity of nucleoli

(2009) C. Martin et al.   JOURNAL OF CELL SCIENCE

Synaptic Activity Induces Dramatic Changes in the Geometry of the Cell Nucleus: Interplay between Nuclear Structure, Histone H3 Phosphorylation, and Nuclear Calcium Signaling

(2009) M. Wittmann et al.   JOURNAL OF NEUROSCIENCE

Proteinopathy-induced neuronal senescence: a hypothesis for brain failure in Alzheimer's and other neurodegenerative diseases

(2009) Todd E Golde et al.   Alzheimers Research & Therapy

The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription

(2008) T. Shimi et al.   GENES & DEVELOPMENT

The integrity of a lamin-B1-dependent nucleoskeleton is a fundamental determinant of RNA synthesis in human cells

(2008) C. W. Tang et al.   JOURNAL OF CELL SCIENCE

Phenotype and Course of Hutchinson–Gilford Progeria Syndrome

(2008) Melissa A. Merideth et al.   NEW ENGLAND JOURNAL OF MEDICINE