In Vivo Osteocyte Mechanotransduction: Recent Developments and Future Directions

The Role of the Osteocyte in Bone and Nonbone Disease

(2017) Lynda F. Bonewald   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

An in vivo model of a mechanically-induced bone marrow lesion

(2017) Jonathan B. Matheny et al.   JOURNAL OF BIOMECHANICS

Correction for Yan et al., Suppression of NF-κB activity via nanoparticle-based siRNA delivery alters early cartilage responses to injury

(2017)   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osteocyte calcium signals encode strain magnitude and loading frequency in vivo

(2017) Karl J. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Post-Traumatic Osteoarthritis in Mice Following Mechanical Injury to the Synovial Joint

(2017) Muhammad Farooq Rai et al.   Scientific Reports

Osteocyte Apoptosis Caused by Hindlimb Unloading is Required to Trigger Osteocyte RANKL Production and Subsequent Resorption of Cortical and Trabecular Bone in Mice Femurs

(2016) Pamela Cabahug-Zuckerman et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A novel rat model for subchondral microdamage in acute knee injury: a potential mechanism in post-traumatic osteoarthritis

(2016) A.J. Ramme et al.   OSTEOARTHRITIS AND CARTILAGE

In vivo mechanical loading rapidly activates β-catenin signaling in osteocytes through a prostaglandin mediated mechanism

(2015) N. Lara-Castillo et al.   BONE

Predicting cortical bone adaptation to axial loading in the mouse tibia

(2015) A. F. Pereira et al.   Journal of the Royal Society Interface

Non-invasive mouse models of post-traumatic osteoarthritis

(2015) B.A. Christiansen et al.   OSTEOARTHRITIS AND CARTILAGE

The primary cilium is a self-adaptable, integrating nexus for mechanical stimuli and cellular signaling

(2015) A. M. Nguyen et al.   Biology Open

Cx43 and Mechanotransduction in Bone

(2015) Lilian I. Plotkin et al.   Current Osteoporosis Reports

An Overview of the Metabolic Functions of Osteocalcin

(2015) Jianwen Wei et al.   Current Osteoporosis Reports

Osteocyte apoptosis is required for production of osteoclastogenic signals following bone fatigue in vivo

(2014) Oran D. Kennedy et al.   BONE

Mechanical Load Increases in Bone Formation via a Sclerostin-Independent Pathway

(2014) Alyson Morse et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Structural and Mechanical Repair of Diffuse Damage in Cortical Bone In Vivo

(2014) Zeynep Seref-Ferlengez et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Early Response of Mouse Joint Tissue to Noninvasive Knee Injury Suggests Treatment Targets

(2014) P. Wu et al.   Arthritis & Rheumatology

The Contribution of Experimental in vivo Models to Understanding the Mechanisms of Adaptation to Mechanical Loading in Bone

(2014) Lee B. Meakin et al.   Frontiers in Endocrinology

Trabecular bone adapts to long-term cyclic loading by increasing stiffness and normalization of dynamic morphometric rates

(2013) Floor M. Lambers et al.   BONE

Osteocytes: Master Orchestrators of Bone

(2013) Mitchell B. Schaffler et al.   CALCIFIED TISSUE INTERNATIONAL

Deletion of a Single β-Catenin Allele in Osteocytes Abolishes the Bone Anabolic Response to Loading

(2013) Behzad Javaheri et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Comparison of loading rate-dependent injury modes in a murine model of post-traumatic osteoarthritis

(2013) Kevin A. Lockwood et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Effects of PTH on osteocyte function

(2012) Teresita Bellido et al.   BONE

Sclerostin antibody inhibits skeletal deterioration due to reduced mechanical loading

(2012) Jordan M Spatz et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Musculoskeletal changes following non-invasive knee injury using a novel mouse model of post-traumatic osteoarthritis

(2012) B.A. Christiansen et al.   OSTEOARTHRITIS AND CARTILAGE

Osteocyte Signaling in Bone

(2012) Mitchell B. Schaffler et al.   Current Osteoporosis Reports

A role for the primary cilium in paracrine signaling between mechanically stimulated osteocytes and mesenchymal stem cells

(2011) David A. Hoey et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Osteocyte primary cilium and its role in bone mechanotransduction

(2010) Sara Temiyasathit et al.   Annals of the New York Academy of Sciences

Dynamics of the transition from osteoblast to osteocyte

(2010) Sarah L. Dallas et al.   Annals of the New York Academy of Sciences

Osteocyte Mechanobiology and Pericellular Mechanics

(2010) Christopher R. Jacobs et al.   Annual Review of Biomedical Engineering

Characterizing a novel and adjustable noninvasive murine joint loading model

(2010) Blandine Poulet et al.   ARTHRITIS AND RHEUMATISM

Cancellous bone adaptation to tibial compression is not sex dependent in growing mice

(2010) Maureen E. Lynch et al.   JOURNAL OF APPLIED PHYSIOLOGY

Early strain-related changes in enzyme activity in osteocytes following bone loading in vivo

(2010) Timothy M. Skerry et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Loading-related increases in prostaglandin production in cores of adult canine cancellous bone in vitro: A role for prostacyclin in adaptive bone remodeling?

(2010) Simon C.F. Rawlinson et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Aged mice have enhanced endocortical response and normal periosteal response compared with young-adult mice following 1 week of axial tibial compression

(2010) Michael D Brodt et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The amazing osteocyte

(2010) Lynda F Bonewald   JOURNAL OF BONE AND MINERAL RESEARCH

Mechanical stimulus alters conformation of type 1 parathyroid hormone receptor in bone cells

(2009) Yan-Liang Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Osteocyte apoptosis and control of bone resorption following ovariectomy in mice

(2009) K.B. Emerton et al.   BONE

Advancing our understanding of osteocyte cell biology

(2009) Dayong Guo et al.   Therapeutic Advances in Musculoskeletal Disease

Osteocyte Apoptosis Controls Activation of Intracortical Resorption in Response to Bone Fatigue

(2008) Luis Cardoso et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Establishment of an Osteocyte-like Cell Line, MLO-Y4

(2006) Yoichi Kato et al.   JOURNAL OF BONE AND MINERAL RESEARCH