RNA Editors, Cofactors, and mRNA Targets: An Overview of the C-to-U RNA Editing Machinery and Its Implication in Human Disease

Post-transcriptional regulation of LINE-1 retrotransposition by AID/APOBEC and ADAR deaminases

(2018) Elisa Orecchini et al.   CHROMOSOME RESEARCH

Sequence, Structure, and Context Preferences of Human RNA Binding Proteins

(2018) Daniel Dominguez et al.   MOLECULAR CELL

Modeling the Embrace of a Mutator: APOBEC Selection of Nucleic Acid Ligands

(2018) Jason D. Salter et al.   TRENDS IN BIOCHEMICAL SCIENCES

A New Chapter in Genetic Medicine: RNA Editing and its Role in Disease Pathogenesis

(2018) Khatuna Gagnidze et al.   TRENDS IN MOLECULAR MEDICINE

Increased RNA Editing May Provide a Source for Autoantigens in Systemic Lupus Erythematosus

(2018) Shalom Hillel Roth et al.   Cell Reports

A Novel RNA Editing Sensor Tool and a Specific Agonist Determine Neuronal Protein Expression of RNA-Edited Glycine Receptors and Identify a Genomic APOBEC1 Dimorphism as a New Genetic Risk Factor of Epilepsy

(2018) Svenja Kankowski et al.   Frontiers in Molecular Neuroscience

Apobec1 complementation factor (A1CF) and RBM47 interact in tissue-specific regulation of C to U RNA editing in mouse intestine and liver

(2018) Valerie Blanc et al.   RNA

Critical review on engineering deaminases for site-directed RNA editing

(2018) Paul Vogel et al.   CURRENT OPINION IN BIOTECHNOLOGY

MODOMICS: a database of RNA modification pathways. 2017 update

(2017) Pietro Boccaletto et al.   NUCLEIC ACIDS RESEARCH

Loss of APOBEC1 RNA-editing function in microglia exacerbates age-related CNS pathophysiology

(2017) Daniel C. Cole et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epitranscriptomic profiling across cell types reveals associations between APOBEC1-mediated RNA editing, gene expression outcomes, and cellular function

(2017) Violeta Rayon-Estrada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

APOBEC1 complementation factor (A1CF) is dispensable for C-to-U RNA editing in vivo

(2017) Elizabeth M. Snyder et al.   RNA

Single-cell transcriptomics reveals specific RNA editing signatures in the human brain

(2017) Ernesto Picardi et al.   RNA

Association between polymorphisms of the APOBEC3G gene and chronic hepatitis B viral infection and hepatitis B virus-related hepatocellular carcinoma

(2017) Xiu-Ting He et al.   WORLD JOURNAL OF GASTROENTEROLOGY

APOBEC3G acts as a therapeutic target in mesenchymal gliomas by sensitizing cells to radiation-induced cell death

(2017) Yu Wang et al.   Oncotarget

APOBEC-mediated mutagenesis in urothelial carcinoma is associated with improved survival, mutations in DNA damage response genes, and immune response

(2017) Alexander P. Glaser et al.   Oncotarget

Deamination-independent restriction of LINE-1 retrotransposition by APOBEC3H

(2017) Yuqing Feng et al.   Scientific Reports

Stem-loop structure preference for site-specific RNA editing by APOBEC3A and APOBEC3G

(2017) Shraddha Sharma et al.   PeerJ

Identification of Parvalbumin Interneurons as Cellular Substrate of Fear Memory Persistence

(2016) Gürsel Çalışkan et al.   CEREBRAL CORTEX

APOBEC3G Expression Correlates with T-Cell Infiltration and Improved Clinical Outcomes in High-grade Serous Ovarian Carcinoma

(2016) B. Leonard et al.   CLINICAL CANCER RESEARCH

APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication

(2016) Vladimir B. Seplyarskiy et al.   GENOME RESEARCH

APOBEC3 proteins can copackage and comutate HIV-1 genomes

(2016) Belete A. Desimmie et al.   NUCLEIC ACIDS RESEARCH

RNA-binding motif protein 47 inhibits Nrf2 activity to suppress tumor growth in lung adenocarcinoma

(2016) T Sakurai et al.   ONCOGENE

RNA binding to APOBEC deaminases; Not simply a substrate for C to U editing

(2016) Harold C. Smith   RNA Biology

Transient overexpression of exogenous APOBEC3A causes C-to-U RNA editing of thousands of genes

(2016) Shraddha Sharma et al.   RNA Biology

The APOBEC Protein Family: United by Structure, Divergent in Function

(2016) Jason D. Salter et al.   TRENDS IN BIOCHEMICAL SCIENCES

RNA editing generates cellular subsets with diverse sequence within populations

(2016) Dewi Harjanto et al.   Nature Communications

The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer

(2016) E. K. Law et al.   Science Advances

The double-domain cytidine deaminase APOBEC3G is a cellular site-specific RNA editing enzyme

(2016) Shraddha Sharma et al.   Scientific Reports

An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers

(2015) Kin Chan et al.   NATURE GENETICS

Intrinsic host restrictions to HIV-1 and mechanisms of viral escape

(2015) Viviana Simon et al.   NATURE IMMUNOLOGY

RNA binding to APOBEC3G induces the disassembly of functional deaminase complexes by displacing single-stranded DNA substrates

(2015) Bogdan Polevoda et al.   NUCLEIC ACIDS RESEARCH

Systemic Lupus Erythematosus - A Disease with A Dysregulated Type I Interferon System

(2015) N. Hagberg et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

APOBECs and virus restriction

(2015) Reuben S. Harris et al.   VIROLOGY

APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages

(2015) Shraddha Sharma et al.   Nature Communications

APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity

(2015) C. Swanton et al.   Cancer Discovery

Re-editing the paradigm of Cytidine (C) to Uridine (U) RNA editing

(2015) Nicolas Fossat et al.   RNA Biology

C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47

(2014) N. Fossat et al.   EMBO REPORTS

The RNA-editing Enzyme APOBEC1 Requires Heterogeneous Nuclear Ribonucleoprotein Q Isoform 6 for Efficient Interaction with Interleukin-8 mRNA

(2014) Yuko Shimizu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Changes in neural network homeostasis trigger neuropsychiatric symptoms

(2014) Aline Winkelmann et al.   JOURNAL OF CLINICAL INVESTIGATION

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Quantification of Deaminase Activity-Dependent and -Independent Restriction of HIV-1 Replication Mediated by APOBEC3F and APOBEC3G through Experimental-Mathematical Investigation

(2014) T. Kobayashi et al.   JOURNAL OF VIROLOGY

Association of rs172378 C1q gene cluster polymorphism with lupus nephritis in Bulgarian patients

(2014) M Radanova et al.   LUPUS

Human APOBEC3F incorporation into human immunodeficiency virus type 1 particles

(2014) Xin Wang et al.   VIRUS RESEARCH

A prevalent cancer susceptibility APOBEC3A hybrid allele bearing APOBEC3B 3′UTR enhances chromosomal DNA damage

(2014) Vincent Caval et al.   Nature Communications

Different Modes of Retrovirus Restriction by Human APOBEC3A and APOBEC3G In Vivo

(2014) Spyridon Stavrou et al.   PLoS Pathogens

The multifaceted roles of RNA binding in APOBEC cytidine deaminase functions

(2014) Kimberly M. Prohaska et al.   Wiley Interdisciplinary Reviews-RNA

Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer

(2014) Sakari Vanharanta et al.   eLife

Genome-wide identification and functional analysis of Apobec-1-mediated C-to-U RNA editing in mouse small intestine and liver

(2014) Valerie Blanc et al.   GENOME BIOLOGY

Modular Transcriptional Repertoire Analyses of Adults With Systemic Lupus Erythematosus Reveal Distinct Type I and Type II Interferon Signatures

(2014) Laurent Chiche et al.   Arthritis & Rheumatology

Elevated APOBEC3B Correlates with Poor Outcomes for Estrogen-Receptor-Positive Breast Cancers

(2014) Anieta M. Sieuwerts et al.   Hormones & Cancer

APOBEC3 inhibits DEAD-END function to regulate microRNA activity

(2013) Sara Ali et al.   BMC MOLECULAR BIOLOGY

APOBEC3 Cytidine Deaminases in Double-Strand DNA Break Repair and Cancer Promotion

(2013) R. Nowarski et al.   CANCER RESEARCH

Endogenous APOBEC3A DNA Cytosine Deaminase Is Cytoplasmic and Nongenotoxic

(2013) Allison M. Land et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

APOBEC3B is an enzymatic source of mutation in breast cancer

(2013) Michael B. Burns et al.   NATURE

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Evidence for APOBEC3B mutagenesis in multiple human cancers

(2013) Michael B Burns et al.   NATURE GENETICS

An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers

(2013) Steven A Roberts et al.   NATURE GENETICS

Binding of RNA by APOBEC3G controls deamination-independent restriction of retroviruses

(2013) Kasandra Bélanger et al.   NUCLEIC ACIDS RESEARCH

Identification and antiviral activity of common polymorphisms in the APOBEC3 locus in human populations

(2013) Nisha K. Duggal et al.   VIROLOGY

Lentivirus restriction by diverse primate APOBEC3A proteins

(2013) Kimberly Schmitt et al.   VIROLOGY

APOBEC3G enhances lymphoma cell radioresistance by promoting cytidine deaminase-dependent DNA repair

(2012) R. Nowarski et al.   BLOOD

An ancient history of gene duplications, fusions and losses in the evolution of APOBEC3 mutators in mammals

(2012) Carsten Münk et al.   BMC EVOLUTIONARY BIOLOGY

Mutational Processes Molding the Genomes of 21 Breast Cancers

(2012) Serena Nik-Zainal et al.   CELL

Human Tribbles 3 Protects Nuclear DNA from Cytidine Deamination by APOBEC3A

(2012) Marie-Ming Aynaud et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

APOBEC3B and AID Have Similar Nuclear Import Mechanisms

(2012) Lela Lackey et al.   JOURNAL OF MOLECULAR BIOLOGY

The Cellular Antiviral Protein APOBEC3G Interacts with HIV-1 Reverse Transcriptase and Inhibits Its Function during Viral Replication

(2012) X. Wang et al.   JOURNAL OF VIROLOGY

Reduced APOBEC3H Variant Anti-Viral Activities Are Associated with Altered RNA Binding Activities

(2012) Anjie Zhen et al.   PLoS One

Transgenerational epigenetic effects of the Apobec1 cytidine deaminase deficiency on testicular germ cell tumor susceptibility and embryonic viability

(2012) V. R. Nelson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

APOBEC1-Mediated Editing and Attenuation of Herpes Simplex Virus 1 DNA Indicate That Neurons Have an Antiviral Role during Herpes Simplex Encephalitis

(2011) P. Gee et al.   JOURNAL OF VIROLOGY

Transcriptome-wide sequencing reveals numerous APOBEC1 mRNA-editing targets in transcript 3′ UTRs

(2011) Brad R Rosenberg et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Metabolic regulation of APOBEC-1 Complementation Factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytes

(2010) Chad A. Galloway et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Apobec-1 Complementation Factor Modulates Liver Regeneration by Post-transcriptional Regulation of Interleukin-6 mRNA Stability

(2010) Valerie Blanc et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternative Splicing and Extensive RNA Editing of Human TPH2 Transcripts

(2010) Maik Grohmann et al.   PLoS One

APOBEC-1-mediated RNA editing

(2010) Valerie Blanc et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Evaluation of C1q genomic region in minority racial groups of lupus

(2009) B Namjou et al.   GENES AND IMMUNITY

Defining APOBEC3 Expression Patterns in Human Tissues and Hematopoietic Cell Subsets

(2009) F. A. Koning et al.   JOURNAL OF VIROLOGY

Human APOBEC1 cytidine deaminase edits HBV DNA

(2009) Minerva Gonzalez et al.   Retrovirology

Glycinergic tonic inhibition of hippocampal neurons with depolarizing GABAergic transmission elicits histopathological signs of temporal lobe epilepsy

(2008) Sabrina A. Eichler et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Comparison of Cellular Ribonucleoprotein Complexes Associated with the APOBEC3F and APOBEC3G Antiviral Proteins

(2008) S. Gallois-Montbrun et al.   JOURNAL OF VIROLOGY

Guidelines for Naming Nonprimate APOBEC3 Genes and Proteins

(2008) R. S. LaRue et al.   JOURNAL OF VIROLOGY

Mouse Apolipoprotein B Editing Complex 3 (APOBEC3) Is Expressed in Germ Cells and Interacts with Dead-End (DND1)

(2008) Chitralekha Bhattacharya et al.   PLoS One

Characterization of APOBEC3G binding to 7SL RNA

(2008) Daniel Bach et al.   Retrovirology

HIV-1 Vif, APOBEC, and Intrinsic Immunity

(2008) Ritu Goila-Gaur et al.   Retrovirology

The AID/APOBEC family of nucleic acid mutators

(2008) Silvestro G Conticello   GENOME BIOLOGY