Gene Regulatory Network Modeling of Macrophage Differentiation Corroborates the Continuum Hypothesis of Polarization States

Lactoferrin-Containing Immunocomplexes Drive the Conversion of Human Macrophages from M2- into M1-like Phenotype

(2018) Chen-Hui Gao et al.   Frontiers in Immunology

Diverse continuum of CD4+T-cell states is determined by hierarchical additive integration of cytokine signals

(2017) Inbal Eizenberg-Magar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulators of the Balance between M1 and M2 Macrophages during Pregnancy

(2017) Yong-Hong Zhang et al.   Frontiers in Immunology

Statistical ensemble of gene regulatory networks of macrophage differentiation

(2016) Filippo Castiglione et al.   BMC BIOINFORMATICS

Mathematical Models for Immunology: Current State of the Art and Future Research Directions

(2016) Raluca Eftimie et al.   BULLETIN OF MATHEMATICAL BIOLOGY

A Network Model to Describe the Terminal Differentiation of B Cells

(2016) Akram Méndez et al.   PLoS Computational Biology

Logical Modeling and Dynamical Analysis of Cellular Networks

(2016) Wassim Abou-Jaoudé et al.   Frontiers in Genetics

Expression and regulation of long noncoding RNAs in TLR4 signaling in mouse macrophages

(2015) Ai-Ping Mao et al.   BMC GENOMICS

IL-10 Production in Macrophages Is Regulated by a TLR-Driven CREB-Mediated Mechanism That Is Linked to Genes Involved in Cell Metabolism

(2015) David E. Sanin et al.   JOURNAL OF IMMUNOLOGY

NF-κB Regulates PD-1 Expression in Macrophages

(2015) Alexander P. R. Bally et al.   JOURNAL OF IMMUNOLOGY

SIGNOR: a database of causal relationships between biological entities

(2015) Livia Perfetto et al.   NUCLEIC ACIDS RESEARCH

IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis

(2015) Rei Nakamura et al.   Nature Communications

A Dynamic Gene Regulatory Network Model That Recovers the Cyclic Behavior of Arabidopsis thaliana Cell Cycle

(2015) Elizabeth Ortiz-Gutiérrez et al.   PLoS Computational Biology

A Minimal Regulatory Network of Extrinsic and Intrinsic Factors Recovers Observed Patterns of CD4+ T Cell Differentiation and Plasticity

(2015) Mariana Esther Martinez-Sanchez et al.   PLoS Computational Biology

Control of Cytokine Production by Human Fc Gamma Receptors: Implications for Pathogen Defense and Autoimmunity

(2015) Lisa T. C. Vogelpoel et al.   Frontiers in Immunology

Macrophage heterogeneity in tissues: phenotypic diversity and functions

(2014) Siamon Gordon et al.   IMMUNOLOGICAL REVIEWS

Immune Complex/Ig Negatively Regulate TLR4-Triggered Inflammatory Response in Macrophages through Fc RIIb-Dependent PGE2 Production

(2014) Y. Zhang et al.   JOURNAL OF IMMUNOLOGY

An essential role for IFN-β in the induction of IFN-stimulated gene expression by LPS in macrophages

(2014) Faruk Sheikh et al.   JOURNAL OF LEUKOCYTE BIOLOGY

FcγRIIb inhibits immune complex-induced VEGF-A production and intranodal lymphangiogenesis

(2014) Menna R. Clatworthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages

(2014) Lisa T. C. Vogelpoel et al.   Nature Communications

Macrophage Plasticity in Skeletal Muscle Repair

(2014) Elena Rigamonti et al.   Biomed Research International

Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance

(2014) Nan Wang et al.   Frontiers in Immunology

Macrophage Polarization in Obesity and Type 2 Diabetes: Weighing Down Our Understanding of Macrophage Function?

(2014) Michael James Kraakman et al.   Frontiers in Immunology

Mathematical Modeling of Pro- and Anti-Inflammatory Signaling in Macrophages

(2014) Shreya Maiti et al.   Processes

The IL-10/STAT3-mediated anti-inflammatory response: recent developments and future challenges

(2013) A. P. Hutchins et al.   Briefings in Functional Genomics

A critical role for suppressor of cytokine signalling 3 in promoting M1 macrophage activation and functionin vitroandin vivo

(2013) Christina E. Arnold et al.   IMMUNOLOGY

Identification of a Unique Hybrid Macrophage-Polarization State following Recovery from Lipopolysaccharide Tolerance

(2013) C. O'Carroll et al.   JOURNAL OF IMMUNOLOGY

Lipopolysaccharide-Induced M2 to M1 Macrophage Transformation for IL-12p70 Production Is Blocked by Candida albicans Mediated Up-Regulation of EBI3 Expression

(2013) Xing-Feng Zheng et al.   PLoS One

Dynamics of Cell-Fate Determination and Patterning in the Vascular Bundles of Arabidopsis thaliana

(2013) Mariana Benítez et al.   PLoS One

Macrophage M1/M2 Polarization Dynamically Adapts to Changes in Cytokine Microenvironments in Cryptococcus neoformans Infection

(2013) M. J. Davis et al.   mBio

TGFβ signaling plays a critical role in promoting alternative macrophage activation

(2012) Dapeng Gong et al.   BMC IMMUNOLOGY

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury

(2012) Atsushi Sato et al.   Journal of Neuroinflammation

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function

(2011) Claire S. Whyte et al.   JOURNAL OF LEUKOCYTE BIOLOGY

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

(2011) Thomas Krausgruber et al.   NATURE IMMUNOLOGY

BoolNet—an R package for generation, reconstruction and analysis of Boolean networks

(2010) Christoph Müssel et al.   BIOINFORMATICS

Control of Macrophage Activation and Function by PPARs

(2010) Ajay Chawla   CIRCULATION RESEARCH

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

(2010) Takashi Satoh et al.   NATURE IMMUNOLOGY

Interleukin-1 (IL-1) Pathway

(2010) A. Weber et al.   Science Signaling

Diversity and Plasticity of Th Cell Types Predicted from Regulatory Network Modelling

(2010) Aurélien Naldi et al.   PLoS Computational Biology

Logical modelling of regulatory networks with GINsim 2.3

(2009) A. Naldi et al.   BIOSYSTEMS

Epigenetic regulation of the alternatively activated macrophage phenotype

(2009) M. Ishii et al.   BLOOD

Fcγ Receptor Cross-linking Stimulates Cell Proliferation of Macrophages via the ERK Pathway

(2009) Yong Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AP-1 Activated by Toll-like Receptors Regulates Expression of IL-23 p19

(2009) Weicheng Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

SOCS1 and SOCS3 in the control of CNS immunity

(2009) Brandi J. Baker et al.   TRENDS IN IMMUNOLOGY

Alternative Activation of Macrophages: An Immunologic Functional Perspective

(2008) Fernando O. Martinez et al.   Annual Review of Immunology

Network modeling of signal transduction: establishing the global view

(2008) Hans A. Kestler et al.   BIOESSAYS

Implementation of a regulatory gene network to simulate the TH1/2 differentiation in an agent-based model of hypersensitivity reactions

(2008) Daniele Santoni et al.   BIOINFORMATICS

The regulatory network of E. coli metabolism as a Boolean dynamical system exhibits both homeostasis and flexibility of response

(2008) Areejit Samal et al.   BMC Systems Biology

Interferon gamma: A master regulator of atherosclerosis

(2008) James E. McLaren et al.   CYTOKINE & GROWTH FACTOR REVIEWS

From phagocyte diversity and activation to probiotics: Back to Metchnikoff

(2008) Alberto Mantovani   EUROPEAN JOURNAL OF IMMUNOLOGY

Elie Metchnikoff: Father of natural immunity

(2008) Siamon Gordon   EUROPEAN JOURNAL OF IMMUNOLOGY

Modelling and analysis of gene regulatory networks

(2008) Guy Karlebach et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY