HIPPO signaling resolves embryonic cell fate conflicts during establishment of pluripotency in vivo

Expanding Actin Rings Zipper the Mouse Embryo for Blastocyst Formation

(2018) Jennifer Zenker et al.   CELL

Making lineage decisions with biological noise: Lessons from the early mouse embryo

(2018) Claire S. Simon et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Actomyosin polarisation through PLC-PKC triggers symmetry breaking of the mouse embryo

(2017) Meng Zhu et al.   Nature Communications

Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo

(2017) Eszter Posfai et al.   eLife

Notch and Hippo signaling converge on Strawberry Notch 1 (Sbno1) to synergistically activate Cdx2 during specification of the trophectoderm

(2017) Yusuke Watanabe et al.   Scientific Reports

Long-Lived Binding of Sox2 to DNA Predicts Cell Fate in the Four-Cell Mouse Embryo

(2016) Melanie D. White et al.   CELL

Heterogeneity in Oct4 and Sox2 Targets Biases Cell Fate in 4-Cell Mouse Embryos

(2016) Mubeen Goolam et al.   CELL

Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse

(2016) Chao Yu et al.   CELL RESEARCH

Roles and regulations of Hippo signaling during preimplantation mouse development

(2016) Hiroshi Sasaki   DEVELOPMENT GROWTH & DIFFERENTIATION

Asymmetric division of contractile domains couples cell positioning and fate specification

(2016) Jean-Léon Maître et al.   NATURE

Rho-associated protein kinase regulates subcellular localisation of Angiomotin and Hippo-signalling during preimplantation mouse embryo development

(2016) Aleksandar I. Mihajlović et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos

(2016) Wei Cui et al.   Scientific Reports

Par-aPKC-dependent and -independent mechanisms cooperatively control cell polarity, Hippo signaling, and cell positioning in 16-cell stage mouse embryos

(2015) Yoshikazu Hirate et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Modular Detection of GFP-Labeled Proteins for Rapid Screening by Electron Microscopy in Cells and Organisms

(2015) Nicholas Ariotti et al.   DEVELOPMENTAL CELL

Cortical Tension Allocates the First Inner Cells of the Mammalian Embryo

(2015) Chaminda R. Samarage et al.   DEVELOPMENTAL CELL

Pulsatile cell-autonomous contractility drives compaction in the mouse embryo

(2015) Jean-Léon Maître et al.   NATURE CELL BIOLOGY

The first two cell-fate decisions of preimplantation mouse embryo development are not functionally independent

(2015) Aleksandar I. Mihajlović et al.   Scientific Reports

Initiation of Hippo signaling is linked to polarity rather than to cell position in the pre-implantation mouse embryo

(2014) Shihadeh Anani et al.   DEVELOPMENT

Inhibition of RHO–ROCK signaling enhances ICM and suppresses TE characteristics through activation of Hippo signaling in the mouse blastocyst

(2014) Kanako Kono et al.   DEVELOPMENTAL BIOLOGY

Notch and Hippo Converge on Cdx2 to Specify the Trophectoderm Lineage in the Mouse Blastocyst

(2014) Teresa Rayon et al.   DEVELOPMENTAL CELL

HIPPO Pathway Members Restrict SOX2 to the Inner Cell Mass Where It Promotes ICM Fates in the Mouse Blastocyst

(2014) Eryn Wicklow et al.   PLoS Genetics

The Hippo Pathway Member Nf2 Is Required for Inner Cell Mass Specification

(2013) Katie Cockburn et al.   CURRENT BIOLOGY

Polarity-Dependent Distribution of Angiomotin Localizes Hippo Signaling in Preimplantation Embryos

(2013) Yoshikazu Hirate et al.   CURRENT BIOLOGY

Temporal reduction of LATS kinases in the early preimplantation embryo prevents ICM lineage differentiation

(2013) C. Lorthongpanich et al.   GENES & DEVELOPMENT

Hippo pathway effector Yap promotes cardiac regeneration

(2013) Mei Xin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Angiomotin prevents pluripotent lineage differentiation in mouse embryos via Hippo pathway-dependent and -independent mechanisms

(2013) Chuen Yan Leung et al.   Nature Communications

Generation and live imaging of an endogenous Cdx2 reporter mouse line

(2012) Katie McDole et al.   GENESIS

Regulation of Insulin-Like Growth Factor Signaling by Yap Governs Cardiomyocyte Proliferation and Embryonic Heart Size

(2011) M. Xin et al.   Science Signaling

Cell Polarity Regulator PARD6B Is Essential for Trophectoderm Formation in the Preimplantation Mouse Embryo1

(2010) Vernadeth B. Alarcon   BIOLOGY OF REPRODUCTION

Resolution of Cell Fate Decisions Revealed by Single-Cell Gene Expression Analysis from Zygote to Blastocyst

(2010) Guoji Guo et al.   DEVELOPMENTAL CELL

The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGF-β-SMAD Pathway

(2010) Xaralabos Varelas et al.   DEVELOPMENTAL CELL

Stage-dependent modes of Pax6-Sox2 epistasis regulate lens development and eye morphogenesis

(2009) A. N. Smith et al.   DEVELOPMENT

The Hippo Signaling Pathway Components Lats and Yap Pattern Tead4 Activity to Distinguish Mouse Trophectoderm from Inner Cell Mass

(2009) Noriyuki Nishioka et al.   DEVELOPMENTAL CELL

Inactivation of aPKCλ Reveals a Context Dependent Allocation of Cell Lineages in Preimplantation Mouse Embryos

(2009) Nicolas Dard et al.   PLoS One

Cdx2 acts downstream of cell polarization to cell-autonomously promote trophectoderm fate in the early mouse embryo

(2007) Amy Ralston et al.   DEVELOPMENTAL BIOLOGY

Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos

(2007) Noriyuki Nishioka et al.   MECHANISMS OF DEVELOPMENT