The first two cell-fate decisions of preimplantation mouse embryo development are not functionally independent

Initiation of Hippo signaling is linked to polarity rather than to cell position in the pre-implantation mouse embryo

(2014) Shihadeh Anani et al.   DEVELOPMENT

Gata6, Nanog and Erk signaling control cell fate in the inner cell mass through a tristable regulatory network

(2014) S. Bessonnard et al.   DEVELOPMENT

The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification

(2014) Thorsten Boroviak et al.   NATURE CELL BIOLOGY

HIPPO Pathway Members Restrict SOX2 to the Inner Cell Mass Where It Promotes ICM Fates in the Mouse Blastocyst

(2014) Eryn Wicklow et al.   PLoS Genetics

The Hippo Pathway Member Nf2 Is Required for Inner Cell Mass Specification

(2013) Katie Cockburn et al.   CURRENT BIOLOGY

Polarity-Dependent Distribution of Angiomotin Localizes Hippo Signaling in Preimplantation Embryos

(2013) Yoshikazu Hirate et al.   CURRENT BIOLOGY

Allocation of inner cells to epiblast vs primitive endoderm in the mouse embryo is biased but not determined by the round of asymmetric divisions (8→16- and 16→32-cells)

(2013) Magdalena Krupa et al.   DEVELOPMENTAL BIOLOGY

Cell-to-cell expression variability followed by signal reinforcement progressively segregates early mouse lineages

(2013) Yusuke Ohnishi et al.   NATURE CELL BIOLOGY

Generating different genetic expression patterns in the early embryo: insights from the mouse model

(2013) Alexander W. Bruce   REPRODUCTIVE BIOMEDICINE ONLINE

Angiomotin prevents pluripotent lineage differentiation in mouse embryos via Hippo pathway-dependent and -independent mechanisms

(2013) Chuen Yan Leung et al.   Nature Communications

Asymmetric Localization of Cdx2 mRNA during the First Cell-Fate Decision in Early Mouse Development

(2013) Maria Skamagki et al.   Cell Reports

The differential response to Fgf signalling in cells internalized at different times influences lineage segregation in preimplantation mouse embryos

(2013) S. A. Morris et al.   Open Biology

Altered subcellular localization of transcription factor TEAD4 regulates first mammalian cell lineage commitment

(2012) P. Home et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Primitive Endoderm Differentiates via a Three-Step Mechanism Involving Nanog and RTK Signaling

(2011) Stephen Frankenberg et al.   DEVELOPMENTAL CELL

Cell fate in the early mouse embryo: sorting out the influence of developmental history on lineage choice

(2011) Samantha A. Morris   REPRODUCTIVE BIOMEDICINE ONLINE

Developmental control of the early mammalian embryo: competition among heterogeneous cells that biases cell fate

(2010) Alexander W Bruce et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx2

(2010) A. Ralston et al.   DEVELOPMENT

FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst

(2010) Y. Yamanaka et al.   DEVELOPMENT

Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal

(2010) K. K. Niakan et al.   GENES & DEVELOPMENT

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF -TRCP

(2010) B. Zhao et al.   GENES & DEVELOPMENT

Origin and formation of the first two distinct cell types of the inner cell mass in the mouse embryo

(2010) S. A. Morris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

From Mouse Egg to Mouse Embryo: Polarities, Axes, and Tissues

(2009) Martin H. Johnson   Annual Review of Cell and Developmental Biology

Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo

(2009) J. Nichols et al.   DEVELOPMENT

Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse

(2009) J. Rossant et al.   DEVELOPMENT

The Hippo Signaling Pathway Components Lats and Yap Pattern Tead4 Activity to Distinguish Mouse Trophectoderm from Inner Cell Mass

(2009) Noriyuki Nishioka et al.   DEVELOPMENTAL CELL

GATA3 Is Selectively Expressed in the Trophectoderm of Peri-implantation Embryo and Directly RegulatesCdx2Gene Expression

(2009) Pratik Home et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Making a firm decision: multifaceted regulation of cell fate in the early mouse embryo

(2009) Magdalena Zernicka-Goetz et al.   NATURE REVIEWS GENETICS

Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst

(2008) B. Plusa et al.   DEVELOPMENT

Dynamic GATA6 expression in primitive endoderm formation and maturation in early mouse embryogenesis

(2008) Kathy Q. Cai et al.   DEVELOPMENTAL DYNAMICS

Loss of Fgfr2 leads to partial XY sex reversal

(2007) Stefan Bagheri-Fam et al.   DEVELOPMENTAL BIOLOGY

Dynamic expression of Lrp2 pathway members reveals progressive epithelial differentiation of primitive endoderm in mouse blastocyst

(2007) François Gerbe et al.   DEVELOPMENTAL BIOLOGY

Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos

(2007) Noriyuki Nishioka et al.   MECHANISMS OF DEVELOPMENT