Umbilical Cord-Derived Mesenchymal Stromal Cells (MSCs) for Knee Osteoarthritis: Repeated MSC Dosing Is Superior to a Single MSC Dose and to Hyaluronic Acid in a Controlled Randomized Phase I/II Trial
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Umbilical Cord-Derived Mesenchymal Stromal Cells (MSCs) for Knee Osteoarthritis: Repeated MSC Dosing Is Superior to a Single MSC Dose and to Hyaluronic Acid in a Controlled Randomized Phase I/II Trial
Authors
Keywords
-
Journal
Stem Cells Translational Medicine
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2018-12-28
DOI
10.1002/sctm.18-0053
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Intraarticularly-Injected Mesenchymal Stem Cells Stimulate Anti-Inflammatory Molecules and Inhibit Pain Related Protein and Chondrolytic Enzymes in a Monoiodoacetate-Induced Rat Arthritis Model
- (2018) Toru Ichiseki et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine
- (2017) Francisco Vizoso et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The quality-of-life burden of knee osteoarthritis in New Zealand adults: A model-based evaluation
- (2017) J. Haxby Abbott et al. PLoS One
- Regeneration of hyaline-like cartilage in situ with SOX9 stimulation of bone marrow-derived mesenchymal stem cells
- (2017) Xiaowei Zhang et al. PLoS One
- Repeated intra-articular injection of allogeneic mesenchymal stem cells causes an adverse response compared to autologous cells in the equine model
- (2017) Amanda-Jo Joswig et al. Stem Cell Research & Therapy
- Anti-Donor Immune Responses Elicited by Allogeneic Mesenchymal Stem Cells and Their Extracellular Vesicles: Are We Still Learning?
- (2017) Paul Lohan et al. Frontiers in Immunology
- Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis: multicenter randomized controlled clinical trial (phase I/II)
- (2016) José M. Lamo-Espinosa et al. Journal of Translational Medicine
- Final results of a phase I–II trial using ex vivo expanded autologous Mesenchymal Stromal Cells for the treatment of osteoarthritis of the knee confirming safety and suggesting cartilage regeneration
- (2016) Robert Soler et al. KNEE
- Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn's disease: a phase 3 randomised, double-blind controlled trial
- (2016) Julián Panés et al. LANCET
- Not single but periodic injections of synovial mesenchymal stem cells maintain viable cells in knees and inhibit osteoarthritis progression in rats
- (2016) N. Ozeki et al. OSTEOARTHRITIS AND CARTILAGE
- Cartilage Regeneration in Osteoarthritic Patients by a Composite of Allogeneic Umbilical Cord Blood-Derived Mesenchymal Stem Cells and Hyaluronate Hydrogel: Results from a Clinical Trial for Safety and Proof-of-Concept with 7 Years of Extended Follow-Up
- (2016) Yong-Beom Park et al. Stem Cells Translational Medicine
- Adipose Mesenchymal Stromal Cell-Based Therapy for Severe Osteoarthritis of the Knee: A Phase I Dose-Escalation Trial
- (2016) Yves-Marie Pers et al. Stem Cells Translational Medicine
- Intra-articular Hyaluronic Acid in Treating Knee Osteoarthritis: a PRISMA-Compliant Systematic Review of Overlapping Meta-analysis
- (2016) Dan Xing et al. Scientific Reports
- Clinical comorbidities, treatment patterns, and direct medical costs of patients with osteoarthritis in usual care: a retrospective claims database analysis
- (2016) Mugdha Gore et al. JOURNAL OF MEDICAL ECONOMICS
- Relative Efficacy of Knee Osteoarthritis Treatments: Are All Placebos Created Equal?
- (2015) Lisa A. Mandl et al. ANNALS OF INTERNAL MEDICINE
- Knee osteoarthritis and all-cause mortality: the Wuchuan Osteoarthritis Study
- (2015) Q. Liu et al. OSTEOARTHRITIS AND CARTILAGE
- Intra-articular administration of xenogeneic neonatal Mesenchymal Stromal Cells early after meniscal injury down-regulates metalloproteinase gene expression in synovium and prevents cartilage degradation in a rabbit model of osteoarthritis
- (2015) N. Saulnier et al. OSTEOARTHRITIS AND CARTILAGE
- Treatment of Knee Osteoarthritis With Allogeneic Bone Marrow Mesenchymal Stem Cells
- (2015) Aurelio Vega et al. TRANSPLANTATION
- Chorion Mesenchymal Stem Cells Show Superior Differentiation, Immunosuppressive, and Angiogenic Potentials in Comparison With Haploidentical Maternal Placental Cells
- (2015) Paz L. González et al. Stem Cells Translational Medicine
- Adult Human Mesenchymal Stem Cells Delivered via Intra-Articular Injection to the Knee Following Partial Medial Meniscectomy
- (2014) C Thomas Vangsness et al. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
- Intra-Articular Injection of Mesenchymal Stem Cells for the Treatment of Osteoarthritis of the Knee: A Proof-of-Concept Clinical Trial
- (2014) Chris Hyunchul Jo et al. STEM CELLS
- Treatment of Knee Osteoarthritis With Autologous Mesenchymal Stem Cells
- (2014) Lluis Orozco et al. TRANSPLANTATION
- Secretion of immunoregulatory cytokines by mesenchymal stem cells
- (2014) Dobroslav Kyurkchiev World Journal of Stem Cells
- Impact of Obesity and Knee Osteoarthritis on Morbidity and Mortality in Older Americans
- (2013) Elena Losina et al. ANNALS OF INTERNAL MEDICINE
- Viscosupplementation for Osteoarthritis of the Knee
- (2013) Anne W.S. Rutjes et al. ANNALS OF INTERNAL MEDICINE
- Articular Cartilage Regeneration With Autologous Peripheral Blood Stem Cells Versus Hyaluronic Acid: A Randomized Controlled Trial
- (2013) Khay-Yong Saw et al. ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY
- Mesenchymal stem cells in joint disease and repair
- (2013) Frank Barry et al. Nature Reviews Rheumatology
- NASHA hyaluronic acid vs methylprednisolone for knee osteoarthritis: a prospective, multi-centre, randomized, non-inferiority trial
- (2013) R. Leighton et al. OSTEOARTHRITIS AND CARTILAGE
- Thrombospondin-2 secreted by human umbilical cord blood-derived mesenchymal stem cells promotes chondrogenic differentiation
- (2013) Sang Young Jeong et al. STEM CELLS
- Antiinflammatory and chondroprotective effects of intraarticular injection of adipose-derived stem cells in experimental osteoarthritis
- (2012) Menno ter Huurne et al. ARTHRITIS AND RHEUMATISM
- Intra-articular Delivery of Purified Mesenchymal Stem Cells from C57BL/6 or MRL/MpJ Superhealer Mice Prevents Posttraumatic Arthritis
- (2012) Brian O. Diekman et al. CELL TRANSPLANTATION
- Intra-articular injection of human mesenchymal stem cells (MSCs) promote rat meniscal regeneration by being activated to express Indian hedgehog that enhances expression of type II collagen
- (2012) M. Horie et al. OSTEOARTHRITIS AND CARTILAGE
- A multicenter, randomized controlled trial comparing a single intra-articular injection of Gel-200, a new cross-linked formulation of hyaluronic acid, to phosphate buffered saline for treatment of osteoarthritis of the knee
- (2012) V. Strand et al. OSTEOARTHRITIS AND CARTILAGE
- Articular Cartilage Regeneration With Autologous Peripheral Blood Progenitor Cells and Hyaluronic Acid After Arthroscopic Subchondral Drilling: A Report of 5 Cases With Histology
- (2011) Khay-Yong Saw et al. ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY
- Application of human umbilical cord blood-derived mesenchymal stem cells in disease models
- (2010) Ju-Yeon Kim World Journal of Stem Cells
- The placebo effect and its determinants in osteoarthritis: meta-analysis of randomised controlled trials
- (2008) W Zhang et al. ANNALS OF THE RHEUMATIC DISEASES
- Why are MSCs therapeutic? New data: new insight
- (2008) AI Caplan JOURNAL OF PATHOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started