Regeneration of hyaline-like cartilage in situ with SOX9 stimulation of bone marrow-derived mesenchymal stem cells

Superficial cells are self-renewing chondrocyte progenitors, which form the articular cartilage in juvenile mice

(2017) Lei Li et al.   FASEB JOURNAL

Development of a bovine decellularized extracellular matrix-biomaterial for nucleus pulposus regeneration

(2015) Svenja Illien-Jünger et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis

(2015) Chia-Feng Liu et al.   NUCLEIC ACIDS RESEARCH

Overexpression of human IGF-I via direct rAAV-mediated gene transfer improves the early repair of articular cartilage defects in vivo

(2014) M Cucchiarini et al.   GENE THERAPY

Use of Tissue Engineering Strategies to Repair Joint Tissues in Osteoarthritis: Viral Gene Transfer Approaches

(2014) Magali Cucchiarini et al.   Current Rheumatology Reports

Tissue-Engineering Strategies to Repair Joint Tissue in Osteoarthritis: Nonviral Gene-Transfer Approaches

(2014) Henning Madry et al.   Current Rheumatology Reports

Cell penetrating recombinant Foxp3 protein enhances Treg function and ameliorates arthritis

(2013) Kentaro Yomogida et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mesenchymal stem cells and their use in therapy: What has been achieved?

(2013) V.B. Fernández Vallone et al.   DIFFERENTIATION

The promotion of cartilage defect repair using adenovirus mediated Sox9 gene transfer of rabbit bone marrow mesenchymal stem cells

(2011) Lei Cao et al.   BIOMATERIALS

Spontaneous hyaline cartilage regeneration can be induced in an osteochondral defect created in the femoral condyle using a novel double-network hydrogel

(2011) Masashi Yokota et al.   BMC MUSCULOSKELETAL DISORDERS

A Class of Human Proteins that Deliver Functional Proteins into Mammalian Cells In Vitro and In Vivo

(2011) James J. Cronican et al.   CHEMISTRY & BIOLOGY

Bone Marrow Mesenchymal Stem Cells: Biological Properties and Their Role in Hematopoiesis and Hematopoietic Stem Cell Transplantation

(2011) Charalampos Pontikoglou et al.   Stem Cell Reviews and Reports

Hyaline Cartilage Regeneration by Combined Therapy of Microfracture and Long-Term Bone Morphogenetic Protein-2 Delivery

(2011) Hee Seok Yang et al.   TISSUE ENGINEERING PART A

SOX9 Governs Differentiation Stage-Specific Gene Expression in Growth Plate Chondrocytes via Direct Concomitant Transactivation and Repression

(2011) Victor Y. L. Leung et al.   PLoS Genetics

International Cartilage Repair Society (ICRS) Recommended Guidelines for Histological Endpoints for Cartilage Repair Studies in Animal Models and Clinical Trials

(2011) Caroline Hoemann et al.   Cartilage

Potent Delivery of Functional Proteins into Mammalian Cellsin Vitroandin VivoUsing a Supercharged Protein

(2010) James J. Cronican et al.   ACS Chemical Biology

SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification

(2010) T. Hattori et al.   DEVELOPMENT

Mesenchymal stem cells: Molecular characteristics and clinical applications

(2010) Cristina Sancricca   World Journal of Stem Cells

The Efficacy of Intra-Articular Hyaluronan Injection after the Microfracture Technique for the Treatment of Articular Cartilage Lesions

(2009) Eric Strauss et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Clinical Efficacy of the Microfracture Technique for Articular Cartilage Repair in the Knee

(2009) Kai Mithoefer et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins

(2009) Hongyan Zhou et al.   Cell Stem Cell

Mesenchymal stem cells and cartilagein situregeneration

(2009) W. Richter   JOURNAL OF INTERNAL MEDICINE

Mammalian cell penetration, siRNA transfection, and DNA transfection by supercharged proteins

(2009) B. R. McNaughton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Inductive Effect of Bone Morphogenetic Protein-4 on Chondral-Lineage Differentiation and In Situ Cartilage Repair

(2009) YangZi Jiang et al.   TISSUE ENGINEERING PART A