Surface molecules of extracellular vesicles secreted by the helminth pathogen Fasciola hepatica direct their internalisation by host cells

RAL GTPases: Biology and Potential as Therapeutic Targets in Cancer

(2017) Chao Yan et al.   PHARMACOLOGICAL REVIEWS

Isolation and characterization of exosomes derived from fertile sheep hydatid cysts

(2017) Mar Siles-Lucas et al.   VETERINARY PARASITOLOGY

Extracellular Vesicles from a Helminth Parasite Suppress Macrophage Activation and Constitute an Effective Vaccine for Protective Immunity

(2017) Gillian Coakley et al.   Cell Reports

Fasciola hepaticaSurface Tegument: Glycoproteins at the Interface of Parasite and Host

(2016) Alessandra Ravidà et al.   MOLECULAR & CELLULAR PROTEOMICS

Sending a message: extracellular vesicles of pathogenic protozoan parasites

(2016) Anthony J. Szempruch et al.   NATURE REVIEWS MICROBIOLOGY

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular Vesicle Biogenesis in Helminths: More than One Route to the Surface?

(2016) Eduardo de la Torre-Escudero et al.   TRENDS IN PARASITOLOGY

Myoferlin is a novel exosomal protein and functional regulator of cancer-derived exosomes

(2016) Arnaud Blomme et al.   Oncotarget

Tegument Glycoproteins and Cathepsins of Newly Excysted Juvenile Fasciola hepatica Carry Mannosidic and Paucimannosidic N-glycans

(2016) Andres Garcia-Campos et al.   PLoS Neglected Tropical Diseases

Detailed Analysis of Protein Topology of Extracellular Vesicles–Evidence of Unconventional Membrane Protein Orientation

(2016) Aleksander Cvjetkovic et al.   Scientific Reports

Carcinogenic Liver Fluke Secretes Extracellular Vesicles That Promote Cholangiocytes to Adopt a Tumorigenic Phenotype

(2015) Sujittra Chaiyadet et al.   JOURNAL OF INFECTIOUS DISEASES

The Extracellular Vesicles of the Helminth Pathogen,Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis

(2015) Krystyna Cwiklinski et al.   MOLECULAR & CELLULAR PROTEOMICS

The Fasciola hepatica genome: gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution

(2015) Krystyna Cwiklinski et al.   GENOME BIOLOGY

Biogenesis and secretion of exosomes

(2014) Joanna Kowal et al.   CURRENT OPINION IN CELL BIOLOGY

Microarray evaluation of the effects of lectin and glycoprotein orientation and data filtering on glycoform discrimination

(2013) Jared Q. Gerlach et al.   Analytical Methods

The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

(2013) Dattatreya Mellacheruvu et al.   NATURE METHODS

Surface Glycosylation Profiles of Urine Extracellular Vesicles

(2013) Jared Q. Gerlach et al.   PLoS One

Tethering the assembly of SNARE complexes

(2013) WanJin Hong et al.   TRENDS IN CELL BIOLOGY

Immunomodulatory molecules of Fasciola hepatica: Candidates for both vaccine and immunotherapeutic development

(2013) John P. Dalton et al.   VETERINARY PARASITOLOGY

Complicated N-linked glycans in simple organisms

(2012) Birgit Schiller et al.   BIOLOGICAL CHEMISTRY

A helminth cathelicidin-like protein suppresses antigen processing and presentation in macrophages via inhibition of lysosomal vATPase

(2012) Mark W. Robinson et al.   FASEB JOURNAL

Differential release of high mannose structural isoforms by fungal and bacterial endo-β-N-acetylglucosaminidases

(2012) Jared Q. Gerlach et al.   Molecular BioSystems

Active Wnt proteins are secreted on exosomes

(2012) Julia Christina Gross et al.   NATURE CELL BIOLOGY

Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells

(2012) Antonio Marcilla et al.   PLoS One

The maintenance and regeneration of the planarian excretory system are regulated by EGFR signaling

(2011) J. C. Rink et al.   DEVELOPMENT

Exploring the Fasciola hepatica tegument proteome

(2011) R. Alan Wilson et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Endocytic Recycling Proteins EHD1 and EHD2 Interact with Fer-1-like-5 (Fer1L5) and Mediate Myoblast Fusion

(2010) Avery D. Posey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Fasciola hepatica Tegumental Antigen Suppresses Dendritic Cell Maturation and Function

(2009) C. M. Hamilton et al.   INFECTION AND IMMUNITY

Helminth Cysteine Proteases Inhibit TRIF-dependent Activation of Macrophages via Degradation of TLR3

(2009) Sheila Donnelly et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Integrated Transcriptomics and Proteomics Analysis of the Secretome of the Helminth PathogenFasciola hepatica

(2009) Mark W. Robinson et al.   MOLECULAR & CELLULAR PROTEOMICS

The Importance of pH in Regulating the Function of the Fasciola hepatica Cathepsin L1 Cysteine Protease

(2009) Jonathan Lowther et al.   PLoS Neglected Tropical Diseases

The N-glycosylation pattern of Caenorhabditis elegans

(2008) Katharina Paschinger et al.   CARBOHYDRATE RESEARCH

Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages

(2008) Sheila Donnelly et al.   FASEB JOURNAL

Ov-APR-1, an aspartic protease from the carcinogenic liver fluke, Opisthorchis viverrini: Functional expression, immunolocalization and subsite specificity

(2008) Sutas Suttiprapa et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Helminth infections: the great neglected tropical diseases

(2008) Peter J. Hotez et al.   JOURNAL OF CLINICAL INVESTIGATION