Dose-biomarker-response modeling of the anticancer effect of ethaselen in a human non-small cell lung cancer xenograft mouse model

Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli

(2016) Christina M Zimanyi et al.   eLife

E2F1 promote the aggressiveness of human colorectal cancer by activating the ribonucleotide reductase small subunit M2

(2015) Zejun Fang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ribonucleotide reductase and cancer: biological mechanisms and targeted therapies

(2014) Y Aye et al.   ONCOGENE

Inhibition of thioredoxin reductase by a novel series of bis-1,2-benzisoselenazol-3(2H)-ones: Organoselenium compounds for cancer therapy

(2012) Jie He et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Selenium-containing thioredoxin reductase inhibitor ethaselen sensitizes non-small cell lung cancer to radiotherapy

(2011) Lei Wang et al.   ANTI-CANCER DRUGS

Ethaselen: a potent mammalian thioredoxin reductase 1 inhibitor and novel organoselenium anticancer agent

(2011) Lihui Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Applying Physiological and Biochemical Concepts to Optimize Biological Drug Development

(2010) PJ Lowe   CLINICAL PHARMACOLOGY & THERAPEUTICS

Thioredxin reductase inhibitor ethaselen increases the drug sensitivity of the colon cancer cell line LoVo towards cisplatin via regulation of G1 phase and reversal of G2/M phase arrest

(2010) Jia-ning Fu et al.   INVESTIGATIONAL NEW DRUGS

A Latent Pharmacokinetic Time Profile to Model Dose-Response Survival Data

(2010) Tom Jacobs et al.   Journal of Biopharmaceutical Statistics

Targeting Thioredoxin Reductase: Anticancer Agents and Chemopreventive Compounds

(2010) H. H. Zeng et al.   Medicinal Chemistry

Potent Activity of Indolequinones against Human Pancreatic Cancer: Identification of Thioredoxin Reductase as a Potential Target

(2009) C. Yan et al.   MOLECULAR PHARMACOLOGY

The inhibitory effect of a novel organoselenium compound BBSKE on the tongue cancer Tca8113 in vitro and in vivo

(2008) Fengxia Xing et al.   ORAL ONCOLOGY