Effects of linagliptin and liraglutide on glucose- and angiotensin II-induced collagen formation and cytoskeleton degradation in cardiac fibroblasts in vitro

NFkappaB activation is essential for miR-21 induction by TGFβ1 in high glucose conditions

(2014) Radha Madhyastha et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hyperglycemia and angiotensin II cooperate to enhance collagen I deposition by cardiac fibroblasts through a ROS-STAT3-dependent mechanism

(2014) Tania Fiaschi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

NF-κB-Mediated Integrin-Linked Kinase Regulation in Angiotensin II-Induced Pro-fibrotic Process in Cardiac Fibroblasts

(2014) Suresh Thakur et al.   LIFE SCIENCES

High level of reactive oxygen species impaired mesenchymal stem cell migration via overpolymerization of F-actin cytoskeleton in systemic lupus erythematosus

(2014) D. Shi et al.   PATHOLOGIE BIOLOGIE

Sitagliptin Reduces Cardiac Apoptosis, Hypertrophy and Fibrosis Primarily by Insulin-Dependent Mechanisms in Experimental type-II Diabetes. Potential Roles of GLP-1 Isoforms

(2014) Belén Picatoste et al.   PLoS One

ROCK1 Deficiency Enhances Protective Effects of Antioxidants against Apoptosis and Cell Detachment

(2014) Michelle Surma et al.   PLoS One

Left ventricular diastolic function in patients with type 2 diabetes treated with a dipeptidyl peptidase-4 inhibitor- a pilot study

(2014) Katia Nogueira et al.   Diabetology & Metabolic Syndrome

Metformin and liraglutide ameliorate high glucose-induced oxidative stress via inhibition of PKC-NAD(P)H oxidase pathway in human aortic endothelial cells

(2013) Battsetseg Batchuluun et al.   ATHEROSCLEROSIS

Angiotensin II upregulates KCa3.1 channels and stimulates cell proliferation in rat cardiac fibroblasts

(2013) Li-Ping Wang et al.   BIOCHEMICAL PHARMACOLOGY

The dipeptidyl peptidase-4 inhibitor-sitagliptin modulates calcium dysregulation, inflammation, and PPARs in hypertensive cardiomyocytes

(2013) T-I Lee et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

LOX-1 in the maintenance of cytoskeleton and proliferation in senescent cardiac fibroblasts

(2013) Xianwei Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Membrane ERα attenuates myocardial fibrosis via RhoA/ROCK-mediated actin remodeling in ovariectomized female infarcted rats

(2013) Tsung-Ming Lee et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Relaxin Prevents Cardiac Fibroblast-Myofibroblast Transition via Notch-1-Mediated Inhibition of TGF-β/Smad3 Signaling

(2013) Chiara Sassoli et al.   PLoS One

Dipeptidyl peptidase-4 inhibitors: Multitarget drugs, not only antidiabetes drugs (D ipeptidyl peptidase -4抑制剂：多靶点药物，不仅仅是降糖药)

(2013) Yunjuan Zhao et al.   Journal of Diabetes

Cardiovascular safety with linagliptin in patients with type 2 diabetes mellitus: a pre-specified, prospective, and adjudicated meta-analysis of a phase 3 programme

(2012) Odd Johansen et al.   Cardiovascular Diabetology

Glucose-independent improvement of vascular dysfunction in experimental sepsis by dipeptidyl-peptidase 4 inhibition

(2012) Swenja Kröller-Schön et al.   CARDIOVASCULAR RESEARCH

DPP-4 Inhibition Attenuates Cardiac Dysfunction and Adverse Remodeling Following Myocardial Infarction in Rats with Experimental Diabetes

(2012) Kim Alexander Connelly et al.   Cardiovascular Therapeutics

The novel DPP-4 inhibitors linagliptin and BI 14361 reduce infarct size after myocardial ischemia/reperfusion in rats

(2012) Berthold Hocher et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Cardioprotective effect of dipeptidyl peptidase-4 inhibitor during ischemia–reperfusion injury

(2012) Kroekkiat Chinda et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Simvastatin disrupts cytoskeleton and decreases cardiac fibroblast adhesion, migration and viability

(2012) Miguel Copaja et al.   TOXICOLOGY

Aspirin suppresses cardiac fibroblast proliferation and collagen formation through downregulation of angiotensin type 1 receptor transcription

(2012) Xianwei Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Regulation of MT1-MMP and MMP-2 by Leptin in Cardiac Fibroblasts Involves Rho/ROCK-Dependent Actin Cytoskeletal Reorganization and Leads to Enhanced Cell Migration

(2011) Kristin Schram et al.   ENDOCRINOLOGY

Effects of DPP-4 inhibition on cardiac metabolism and function in mice

(2011) M. Lenski et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Regulation of (Pro)Renin Receptor Expression by Glucose-Induced Mitogen-Activated Protein Kinase, Nuclear Factor-κB, and Activator Protein-1 Signaling Pathways

(2010) Jiqian Huang et al.   ENDOCRINOLOGY

Angiotensin-converting enzyme 2 activation protects against hypertension-induced cardiac fibrosis involving extracellular signal-regulated kinases

(2010) Anderson J. Ferreira et al.   EXPERIMENTAL PHYSIOLOGY

Regulation of cardiac fibroblast collagen synthesis by adenosine: roles for Epac and PI3K

(2009) Francisco Villarreal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Myocardial fibrosis and apoptosis, but not inflammation, are present in long-term experimental diabetes

(2009) S. Ares-Carrasco et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Differential regulation of collagen types I and III expression in cardiac fibroblasts by AGEs through TRB3/MAPK signaling pathway

(2008) M. Tang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES