Sitagliptin Reduces Cardiac Apoptosis, Hypertrophy and Fibrosis Primarily by Insulin-Dependent Mechanisms in Experimental type-II Diabetes. Potential Roles of GLP-1 Isoforms

Antihyperglycemic effects of ASP8497 in streptozotocin-nicotinamide induced diabetic rats: comparison with other dipeptidyl peptidase-IV inhibitors

(2014) Atsuo Tahara et al.   Pharmacological Reports

Impaired mitochondrial biogenesis due to dysfunctional adiponectin-AMPK-PGC-1α signaling contributing to increased vulnerability in diabetic heart

(2013) Wenjun Yan et al.   BASIC RESEARCH IN CARDIOLOGY

Protective Effects of GLP-1 on Glomerular Endothelium and Its Inhibition by PKC  Activation in Diabetes

(2012) A. Mima et al.   DIABETES

The incretin hormones: from scientific discovery to practical therapeutics

(2012) S. Mudaliar et al.   DIABETOLOGIA

Alogliptin benzoate for the treatment of type 2 diabetes

(2012) Marc Rendell et al.   EXPERT OPINION ON PHARMACOTHERAPY

Proteome changes in the myocardium of experimental chronic diabetes and hypertension

(2012) S. Ares-Carrasco et al.   Journal of Proteomics

Glucagon-like peptide-1 inhibits angiotensin II-induced mesangial cell damage via protein kinase A

(2012) Yuji Ishibashi et al.   MICROVASCULAR RESEARCH

DIOL Triterpenes Block Profibrotic Effects of Angiotensin II and Protect from Cardiac Hypertrophy

(2012) Ruben Martín et al.   PLoS One

Differentiating among incretin-based therapies in the management of patients with type 2 diabetes mellitus

(2012) Michael Cobble   Diabetology & Metabolic Syndrome

Antiapoptotic effects of GLP-1 in murine HL-1 cardiomyocytes

(2011) Susana Ravassa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Enteroendocrine cells and lipid absorption

(2011) Georg Mellitzer et al.   CURRENT OPINION IN LIPIDOLOGY

Left ventricle structural remodelling in the prediabetic Goto-Kakizaki rat

(2011) Alicia D'Souza et al.   EXPERIMENTAL PHYSIOLOGY

Sitagliptin Augments Protective Effects of GLP-1 against Advanced Glycation End Product Receptor Axis in Endothelial Cells

(2011) Y. Ishibashi et al.   HORMONE AND METABOLIC RESEARCH

Effects of DPP-4 inhibition on cardiac metabolism and function in mice

(2011) M. Lenski et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The myocardial infarct size-limiting effect of sitagliptin is PKA-dependent, whereas the protective effect of pioglitazone is partially dependent on PKA

(2010) Yumei Ye et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Glucagon-Like Peptide 1 Prevents Reactive Oxygen Species–Induced Endothelial Cell Senescence Through the Activation of Protein Kinase A

(2010) Hisko Oeseburg et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Metformin attenuates cardiac fibrosis by inhibiting the TGFβ1–Smad3 signalling pathway

(2010) Han Xiao et al.   CARDIOVASCULAR RESEARCH

DPP-4 Inhibition by Sitagliptin Improves the Myocardial Response to Dobutamine Stress and Mitigates Stunning in a Pilot Study of Patients With Coronary Artery Disease

(2010) Philip A. Read et al.   Circulation-Cardiovascular Imaging

Genetic Deletion or Pharmacological Inhibition of Dipeptidyl Peptidase-4 Improves Cardiovascular Outcomes After Myocardial Infarction in Mice

(2010) M. Sauve et al.   DIABETES

Glucagon-like peptide-1-based therapies and cardiovascular disease: looking beyond glycaemic control

(2010) P. Anagnostis et al.   DIABETES OBESITY & METABOLISM

Sitagliptin

(2010) Sohita Dhillon   DRUGS

The Decreased Expression of Peroxisome Proliferator-activated Receptors δ (PPARδ) is Reversed by Digoxin in the Heart of Diabetic Rats

(2010) S. C. Fan et al.   HORMONE AND METABOLIC RESEARCH

Cannabidiol Attenuates Cardiac Dysfunction, Oxidative Stress, Fibrosis, and Inflammatory and Cell Death Signaling Pathways in Diabetic Cardiomyopathy

(2010) Mohanraj Rajesh et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Glucagon Like Peptide-1-Directed Human Embryonic Stem Cells Differentiation Into Insulin-Producing Cells Via Hedgehog, cAMP, and PI3K Pathways

(2010) Hongxiang Hui et al.   PANCREAS

Myocardial fibrosis and apoptosis, but not inflammation, are present in long-term experimental diabetes

(2009) S. Ares-Carrasco et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Peroxisome proliferator-activated receptor β stimulation induces rapid cardiac growth and angiogenesis via direct activation of calcineurin

(2009) Nicole Wagner et al.   CARDIOVASCULAR RESEARCH

Peroxisome Proliferator-Activated Receptor δ Regulates Extracellular Matrix and Apoptosis of Vascular Smooth Muscle Cells Through the Activation of Transforming Growth Factor-β1/Smad3

(2009) Hyo Jung Kim et al.   CIRCULATION RESEARCH

GLP-1R Agonist Liraglutide Activates Cytoprotective Pathways and Improves Outcomes After Experimental Myocardial Infarction in Mice

(2009) M. H. Noyan-Ashraf et al.   DIABETES

Standards of Medical Care in Diabetes--2009

(2009)   DIABETES CARE

Peroxisome proliferator-activated receptor beta/delta (PPARβ/δ) acts as regulator of metabolism linked to multiple cellular functions

(2009) Kay-Dietrich Wagner et al.   PHARMACOLOGY & THERAPEUTICS

Insulin-like actions of glucagon-like peptide-1: a dual receptor hypothesis

(2009) Eva Tomas et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Diabetic Cardiomyopathy: Insights into Pathogenesis, Diagnostic Challenges, and Therapeutic Options

(2008) Ashish Aneja et al.   AMERICAN JOURNAL OF MEDICINE

Cardioprotective and Vasodilatory Actions of Glucagon-Like Peptide 1 Receptor Are Mediated Through Both Glucagon-Like Peptide 1 Receptor–Dependent and –Independent Pathways

(2008) Kiwon Ban et al.   CIRCULATION

Glucose-lowering activity of the dipeptidyl peptidase-4 inhibitor saxagliptin in drug-naive patients with type 2 diabetes

(2008) J. Rosenstock et al.   DIABETES OBESITY & METABOLISM