Enhancing the Accumulation of Polymer Micelles by Selectively Dilating Tumor Blood Vessels with NO for Highly Effective Cancer Treatment

Magnesium silicide nanoparticles as a deoxygenation agent for cancer starvation therapy

(2017) Chen Zhang et al.   Nature Nanotechnology

Controllable NO release from Cu1.6S nanoparticle decomposition of S-nitrosoglutathiones following photothermal disintegration of polymersomes to elicit cerebral vasodilatory activity

(2017) Po-Tsung Kao et al.   Chemical Science

Precise Polymerization of a Highly Tumor Microenvironment-Responsive Nanoplatform for Strongly Enhanced Intracellular Drug Release

(2016) Yi Wang et al.   ACS Applied Materials & Interfaces

Artificial Virus Delivers CRISPR-Cas9 System for Genome Editing of Cells in Mice

(2016) Ling Li et al.   ACS Nano

Codelivery of a π-π Stacked Dual Anticancer Drug Combination with Nanocarriers for Overcoming Multidrug Resistance and Tumor Metastasis

(2016) Xiao Wei et al.   ADVANCED FUNCTIONAL MATERIALS

Folic-Acid-Mediated Functionalized Gold Nanocages for Targeted Delivery of Anti-miR-181b in Combination of Gene Therapy and Photothermal Therapy against Hepatocellular Carcinoma

(2016) Shengnan Huang et al.   ADVANCED FUNCTIONAL MATERIALS

Hierarchical Targeting Strategy for Enhanced Tumor Tissue Accumulation/Retention and Cellular Internalization

(2016) Sheng Wang et al.   ADVANCED MATERIALS

Retinal-conjugated pH-sensitive micelles induce tumor senescence for boosting breast cancer chemotherapy

(2016) Yijuan Zhang et al.   BIOMATERIALS

A Retrospective 30 Years After Discovery of the Enhanced Permeability and Retention Effect of Solid Tumors: Next-Generation Chemotherapeutics and Photodynamic Therapy-Problems, Solutions, and Prospects

(2016) Hiroshi Maeda et al.   MICROCIRCULATION

Hyaluronidase To Enhance Nanoparticle-Based Photodynamic Tumor Therapy

(2016) Hua Gong et al.   NANO LETTERS

Tailoring nanoparticle designs to target cancer based on tumor pathophysiology

(2016) Edward A. Sykes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy

(2016) Hong-Jun Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA-controlled dynamic colloidal nanoparticle systems for mediating cellular interaction

(2016) S. Ohta et al.   SCIENCE

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Tuning Endothelial Permeability with Functionalized Nanodiamonds

(2015) Magdiel I. Setyawati et al.   ACS Nano

Tumor-Specific Formation of Enzyme-Instructed Supramolecular Self-Assemblies as Cancer Theranostics

(2015) Peng Huang et al.   ACS Nano

Toward a full understanding of the EPR effect in primary and metastatic tumors as well as issues related to its heterogeneity

(2015) Hiroshi Maeda   ADVANCED DRUG DELIVERY REVIEWS

Size Changeable Nanocarriers with Nuclear Targeting for Effectively Overcoming Multidrug Resistance in Cancer Therapy

(2015) Xing Guo et al.   ADVANCED MATERIALS

Acylsulfonamide-Functionalized Zwitterionic Gold Nanoparticles for Enhanced Cellular Uptake at Tumor pH

(2015) Tsukasa Mizuhara et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Facile Generation of Tumor-pH-Labile Linkage-Bridged Block Copolymers for Chemotherapeutic Delivery

(2015) Chun-Yang Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Deoxycholate bile acid directed synthesis of branched Au nanostructures for near infrared photothermal ablation

(2015) Dong-Hyun Kim et al.   BIOMATERIALS

Multi-functional self-fluorescent unimolecular micelles for tumor-targeted drug delivery and bioimaging

(2015) Guojun Chen et al.   BIOMATERIALS

Control of hierarchical polymer mechanics with bioinspired metal-coordination dynamics

(2015) Scott C. Grindy et al.   NATURE MATERIALS

Dual-pH Sensitive Charge-Reversal Polypeptide Micelles for Tumor-Triggered Targeting Uptake and Nuclear Drug Delivery

(2015) Shi-Song Han et al.   Small

Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors

(2014) Zhishen Ge et al.   BIOMATERIALS

Dual-Responsive Polymer Micelles for Target-Cell-Specific Anticancer Drug Delivery

(2014) Xing Guo et al.   CHEMISTRY OF MATERIALS

EPR: Evidence and fallacy

(2014) Joseph W. Nichols et al.   JOURNAL OF CONTROLLED RELEASE

A smart and versatile theranostic nanomedicine platform based on nanoporphyrin

(2014) Yuanpei Li et al.   Nature Communications

pH-triggered intracellular release from actively targeting polymer micelles

(2013) Xing Guo et al.   BIOMATERIALS

Factors controlling the pharmacokinetics, biodistribution and intratumoral penetration of nanoparticles

(2013) Mark J. Ernsting et al.   JOURNAL OF CONTROLLED RELEASE

S-Nitrosated Human Serum Albumin Dimer is not only a Novel Anti-Tumor Drug but also a Potentiator for Anti-Tumor Drugs with Augmented EPR Effects

(2012) Yu Ishima et al.   BIOCONJUGATE CHEMISTRY

Lipopolysaccharide Neutralizing Peptide–Porphyrin Conjugates for Effective Photoinactivation and Intracellular Imaging of Gram-Negative Bacteria Strains

(2012) Fang Liu et al.   BIOCONJUGATE CHEMISTRY

Drug release kinetics, cell uptake, and tumor toxicity of hybrid VVVVVVKK peptide-assembled polylactide nanoparticles

(2012) Esmaiel Jabbari et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Anticancer nanomedicine and tumor vascular permeability; Where is the missing link?

(2012) Sebastien Taurin et al.   JOURNAL OF CONTROLLED RELEASE

Specific Detection of Integrin αvβ3 by Light-Up Bioprobe with Aggregation-Induced Emission Characteristics

(2012) Haibin Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Polyvalent Dendrimer-Methotrexate as a Folate Receptor-Targeted Cancer Therapeutic

(2012) Thommey P. Thomas et al.   MOLECULAR PHARMACEUTICS

pH-Titratable Superparamagnetic Iron Oxide for Improved Nanoparticle Accumulation in Acidic Tumor Microenvironments

(2011) Samuel H. Crayton et al.   ACS Nano

Targeted drug delivery to tumors: Myths, reality and possibility

(2011) You Han Bae et al.   JOURNAL OF CONTROLLED RELEASE

Blood clearance and tissue distribution of PEGylated and non-PEGylated gold nanorods after intravenous administration in rats

(2011) Daniëlle PK Lankveld et al.   Nanomedicine

Delivery of Molecular and Nanoscale Medicine to Tumors: Transport Barriers and Strategies

(2011) Vikash P. Chauhan et al.   Annual Review of Chemical and Biomolecular Engineering

The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

(2010) Jun Fang et al.   ADVANCED DRUG DELIVERY REVIEWS

Cancer metabolism: The Warburg effect today

(2010) Leonardo M.R. Ferreira   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Folate-conjugated amphiphilic hyperbranched block copolymers based on Boltorn® H40, poly(l-lactide) and poly(ethylene glycol) for tumor-targeted drug delivery

(2009) Mani Prabaharan et al.   BIOMATERIALS

Extracellularly Activated Nanocarriers: A New Paradigm of Tumor Targeted Drug Delivery

(2009) Emily Gullotti et al.   MOLECULAR PHARMACEUTICS