Overexpression of CCDC69 activates p14ARF/MDM2/p53 pathway and confers cisplatin sensitivity

Ovarian cancer spheroid shrinkage following continuous exposure to cisplatin is a function of spheroid diameter

(2017) Laura M. Tanenbaum et al.   GYNECOLOGIC ONCOLOGY

Oncofertility for women with gynecologic malignancies

(2017) Jessica L. Chan et al.   GYNECOLOGIC ONCOLOGY

Serous tubal intraepithelial neoplasia: the concept and its application

(2017) Emily E K Meserve et al.   MODERN PATHOLOGY

Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function

(2017) Naoe T. Nihira et al.   Science Signaling

Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function

(2017) Naoe T. Nihira et al.   Science Signaling

Pharmacology and toxicology of the novel investigational agent Cantrixil (TRX-E-002-1)

(2016) Muhammad Wasif Saif et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Coiled-coil domain-containing protein 8 inhibits the invasiveness and migration of non–small cell lung cancer cells

(2016) Gui-Yang Jiang et al.   HUMAN PATHOLOGY

The coiled-coil domain containing protein Ccdc136b antagonizes maternal Wnt/β-catenin activity during zebrafish dorsoventral axial patterning

(2016) Shi Wei et al.   Journal of Genetics and Genomics

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

(2016) Panagiotis Galanos et al.   NATURE CELL BIOLOGY

Energetic Landscape of MDM2-p53 Interactions by Computational Mutagenesis of the MDM2-p53 Interaction

(2016) Kelly M. Thayer et al.   PLoS One

p14 expression differences in ovarian benign, borderline and malignant epithelial tumors

(2016) Vinicius Duarte Cabral et al.   Journal of Ovarian Research

Regulation of the MDM2-p53 pathway by the nucleolar protein CSIG in response to nucleolar stress

(2016) Nan Xie et al.   Scientific Reports

Senescence Process in Primary Wilms' Tumor Cell Culture Induced by p53 Independent p21 Expression

(2016) Korkiat Theerakitthanakul et al.   Journal of Cancer

Role of p14ARF-HDM2-p53 axis in SOX6-mediated tumor suppression

(2015) J Wang et al.   ONCOGENE

Characterization of the novel tumor-suppressor gene CCDC67 in papillary thyroid carcinoma

(2015) De-Tao Yin et al.   Oncotarget

Pokemon enhances proliferation, cell cycle progression and anti-apoptosis activity of colorectal cancer independently of p14ARF–MDM2–p53 pathway

(2014) Yi Zhao et al.   MEDICAL ONCOLOGY

Coiled-coil domain containing 68 (CCDC68) demonstrates a tumor-suppressive role in pancreatic ductal adenocarcinoma

(2014) N Radulovich et al.   ONCOGENE

p53 protein aggregation promotes platinum resistance in ovarian cancer

(2014) Y Yang-Hartwich et al.   ONCOGENE

Different expression pattern and significance of p14ARF-Mdm2-p53 pathway and Bmi-1 exist between gastric cardia and distal gastric adenocarcinoma

(2012) Dongying Yao et al.   HUMAN PATHOLOGY

p14ARF-induced Apoptosis in p53 Protein-deficient Cells Is Mediated by BH3-only Protein-independent Derepression of Bak Protein through Down-regulation of Mcl-1 and Bcl-xLProteins

(2012) Annika Müer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coiled Coil Domain-containing Protein 56 (CCDC56) Is a Novel Mitochondrial Protein Essential for CytochromecOxidase Function

(2012) Susana Peralta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of a novel coiled-coil domain-containing protein CCDC69 in regulating central spindle assembly

(2010) Debjani Pal et al.   CELL CYCLE

Regulation of Mitochondrial Apoptotic Events by p53-mediated Disruption of Complexes between Antiapoptotic Bcl-2 Members and Bim

(2010) Jie Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytoplasmic p21 expression levels determine cisplatin resistance in human testicular cancer

(2010) Roelof Koster et al.   JOURNAL OF CLINICAL INVESTIGATION

Systematic genetic dissection of p14ARF-mediated mitochondrial cell death signaling reveals a key role for p21CDKN1 and the BH3-only protein Puma/bbc3

(2010) Philipp G. Hemmati et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Gene Expression Profile for Predicting Survival in Advanced-Stage Serous Ovarian Cancer Across Two Independent Datasets

(2010) Kosuke Yoshihara et al.   PLoS One

Novel Molecular Subtypes of Serous and Endometrioid Ovarian Cancer Linked to Clinical Outcome

(2008) R. W. Tothill et al.   CLINICAL CANCER RESEARCH