Dynamic ubiquitylation of Sox2 regulates proteostasis and governs neural progenitor cell differentiation
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Title
Dynamic ubiquitylation of Sox2 regulates proteostasis and governs neural progenitor cell differentiation
Authors
Keywords
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Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-11-01
DOI
10.1038/s41467-018-07025-z
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Note: Only part of the references are listed.- TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling
- (2017) Bin Wang et al. NATURE
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- (2016) Tycho E. T. Mevissen et al. NATURE
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- (2015) J Wang et al. CELL DEATH AND DIFFERENTIATION
- Synthesis and Evaluation of Derivatives of the Proteasome Deubiquitinase Inhibitor b-AP15
- (2015) Xin Wang et al. Chemical Biology & Drug Design
- Deubiquitinating enzymes regulate Hes1 stability and neuronal differentiation
- (2015) Taeko Kobayashi et al. FEBS Journal
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- (2015) Mateusz Cyryl Ambrozkiewicz et al. FEBS LETTERS
- Distinct and overlapping functions of the cullin E3 ligase scaffolding proteins CUL4A and CUL4B
- (2015) Jeffrey Hannah et al. GENE
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- (2015) Lin Yuan et al. NATURE CELL BIOLOGY
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- (2015) Ting Shen et al. Neuroscience Bulletin
- Phosphorylation of ETS1 by Src Family Kinases Prevents Its Recognition by the COP1 Tumor Suppressor
- (2014) Gang Lu et al. CANCER CELL
- Cezanne (OTUD7B) regulates HIF-1 homeostasis in a proteasome-independent manner
- (2014) A. Bremm et al. EMBO REPORTS
- A Methylation-Phosphorylation Switch Determines Sox2 Stability and Function in ESC Maintenance or Differentiation
- (2014) Lan Fang et al. MOLECULAR CELL
- OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis
- (2013) Tycho E.T. Mevissen et al. CELL
- Cezanne Regulates Inflammatory Responses to Hypoxia in Endothelial Cells by Targeting TRAF6 for Deubiquitination
- (2013) Le A. Luong et al. CIRCULATION RESEARCH
- OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3
- (2013) Hongbo Hu et al. NATURE
- Regulation of Pluripotency and Cellular Reprogramming by the Ubiquitin-Proteasome System
- (2012) Shannon M. Buckley et al. Cell Stem Cell
- MLN4924: a novel first-in-class inhibitor of NEDD8-activating enzyme for cancer therapy
- (2012) Steffan T Nawrocki et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses
- (2012) Yichen Shi et al. NATURE NEUROSCIENCE
- Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice
- (2011) Domenico Migliorini et al. JOURNAL OF CLINICAL INVESTIGATION
- Ars2 maintains neural stem-cell identity through direct transcriptional activation of Sox2
- (2011) Celia Andreu-Agullo et al. NATURE
- COP1 is a tumour suppressor that causes degradation of ETS transcription factors
- (2011) Alberto C. Vitari et al. NATURE
- Control of Drosophila endocycles by E2F and CRL4CDT2
- (2011) Norman Zielke et al. NATURE
- Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells
- (2011) Zhi Huang et al. NATURE CELL BIOLOGY
- Phosphorylation of E3 Ligase Smurf1 Switches Its Substrate Preference in Support of Axon Development
- (2011) Pei-lin Cheng et al. NEURON
- Deubiquitinases in cancer: new functions and therapeutic options
- (2011) J M Fraile et al. ONCOGENE
- Deubiquitination of EGFR by Cezanne-1 contributes to cancer progression
- (2011) F Pareja et al. ONCOGENE
- Will the Ubiquitin System Furnish as Many Drug Targets as Protein Kinases?
- (2010) Philip Cohen et al. CELL
- Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun
- (2010) Joerg D Hoeck et al. NATURE NEUROSCIENCE
- Phosphorylation of Sox2 Cooperates in Reprogramming to Pluripotent Stem Cells
- (2010) Chul-Ho Jeong et al. STEM CELLS
- Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh
- (2009) Rebecca Favaro et al. NATURE NEUROSCIENCE
- Acetylation of Sox2 Induces its Nuclear Export in Embryonic Stem Cells
- (2009) Gretchen A. Baltus et al. STEM CELLS
- Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells
- (2008) Xi Chen et al. CELL
- Impaired generation of mature neurons by neural stem cells from hypomorphic Sox2 mutants
- (2008) M. Cavallaro et al. DEVELOPMENT
- COP1 Functions as a FoxO1 Ubiquitin E3 Ligase to Regulate FoxO1-mediated Gene Expression
- (2008) Satomi Kato et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein
- (2008) Xudong Zhao et al. NATURE CELL BIOLOGY
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